Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection

    Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  3. Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  4. Published

    Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation

    Mortensen, Janni Støvring, Bohr, S. S. R., Krog, Lasse Skjoldborg, Bøtker, Johan Peter, Kapousidou, V., Saaby, Lasse, Hatzakis, Nikos, Nielsen, Hanne Mørck, Nguyen, Duc Ninh & Rønholt, Stine, 2024, In: Scientific Reports. 14, 1, 17 p., 7665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Overcoming the Mucus barrier

    Mortensen, Janni Støvring, Stie, Mai Bay, Rønholt, Stine & Nielsen, Hanne Mørck, 2021, Organelle and Molecular Targeting. Milane, L. S. & Amiji, M. M. (eds.). CRC Press, p. 355-379 25 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. Published

    Effects of prophylactic antibiotics administration on barrier properties of intestinal mucosa and mucus from preterm born piglets

    Mortensen, Janni Støvring, Nguyen, Duc Ninh, Nielsen, Hanne Mørck & Rønholt, Stine, 2023, In: Drug Delivery and Translational Research. 13, p. 1456–1469

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Physical and barrier changes in gastrointestinal mucus induced by the permeation enhancer sodium 8-[(2-hydroxybenzoyl)amino]octanoate (SNAC)

    Mortensen, Janni Støvring, Bohr, S. S. R., Rønholt, Stine, Hatzakis, Nikos, Saaby, Lasse & Nielsen, Hanne Mørck, 2022, In: Journal of Controlled Release. 352, p. 163-178 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Lysine-Based α-peptide/β-peptoid peptidomimetics: Influence of hydrophobicity, fluorination and distribution of cationic charge on antimicrobial activity and cytotoxicity

    Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro, Nielsen, Hanne Mørck & Franzyk, Henrik, 2017, In: ChemMedChem. 12, p. 312-318 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

    Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

    Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement

    Malekkhaiat Häffner, S., Nyström, L., Browning, K. L., Nielsen, Hanne Mørck, Strömstedt, A. A., van der Plas, Mariena J.A., Schmidtchen, A. & Malmsten, Martin, 1 May 2019, In: A C S Applied Materials and Interfaces. 11, 17, p. 15389-15400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum

    Madsen, H. B., Ifversen, P., Madsen, F., Larsen, Birger Brodin, Hausser, I. & Nielsen, Hanne Mørck, 2009, In: The AAPS Journal. 11, 4, p. 728-739

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems

    Madsen, H. B., Arboe-Andersen, H. M., Rozlosnik, N., Madsen, F., Ifversen, P., Kasimova, M. R. & Nielsen, Hanne Mørck, 2010, In: Biochimica et Biophysica Acta - Biomembranes. 1798, p. 1779-1789

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Farvel til sprøjten: udvikling af vaccineplaster med nanopartikler

    Madsen, H. B., Ifversen, P., Madsen, F., Manniche, S. & Nielsen, Hanne Mørck, 2007, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journal › Journal article › Communication

  15. Published

    Farvel til sprøjten: udvikling af vaccineplaster med nanopartikler

    Madsen, H. B., Ifversen, P., Madsen, F., Manniche, S. & Nielsen, Hanne Mørck, 2007, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journal › Journal article › Communication

  16. In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum

    Madsen, H. B., Ifversen, P., Madsen, F., Larsen, B. B., Hausser, I. & Nielsen, Hanne Mørck, 2009, In: The AAPS Journal. 11, 4, p. 728-739

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems

    Madsen, H. B., Arboe-Andersen, H. M., Rozlosnik, N., Madsen, F., Ifversen, P., Kasimova, M. R. & Nielsen, Hanne Mørck, Sep 2010, In: Biochimica et biophysica acta. 1798, 9, p. 1779-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Investigation of the interaction between modified ISCOMs and stratum corneum lipid model systems

    Madsen, H. B., Arboe-Andersen, H. M., Rozlosnik, N., Madsen, F., Ifversen, P., Kasimova, M. R. & Nielsen, Hanne Mørck, 2010, In: Biochimica et Biophysica Acta - Biomembranes. 1798, p. 1779-1789

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Innovative Methods and Applications in Mucoadhesion Research

    Mackie, A. R., Goycoolea, F. M., Menchicchi, B., Caramella, C. M., Saporito, F., Lee, S., Stephansen, K., Chronakis, I. S., Hiorth, M., Adamczak, M., Waldner, M., Nielsen, Hanne Mørck & Marcelloni, L., Aug 2017, In: Macromolecular Bioscience. 17, 8, 32 p., 1600534.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing

    Liu, X., Nielsen, L. H., Klodzinska, S. N., Nielsen, Hanne Mørck, Qu, H., Christensen, L. P., Rantanen, Jukka & Yang, Mingshi, Feb 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 123, p. 42-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The impact of particle preparation methods and polymorphic stability of lipid excipients on protein distribution in microparticles

    Liu, J., Christophersen, P. C., Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Dec 2017, In: Drug Development and Industrial Pharmacy. 43, 12, p. 2032-2042 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

    Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Oral delivery of peptides and proteins using lipid-based drug delivery systems

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , 2012, In: Expert Opinion on Drug Delivery. 9, 10, p. 1289-304 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems

    Li, P., Nielsen, Hanne Mørck, Fano, M. & Mullertz, Anette , Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2689-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

    Kłodzińska, S. N., Molchanova, N., Franzyk, Henrik, Hansen, Paul Robert, Damborg, Peter Panduro & Nielsen, Hanne Mørck, Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles

    Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Nanogel delivery systems for cationic peptides: More than a ‘One Size Fits All’ solution

    Kłodzińska, S. N., Wang, Qiuyue, Molchanova, N., Mahmoudi, N., Vallooran, J. J., Hansen, Paul Robert, Jenssen, H. & Nielsen, Hanne Mørck, 2024, In: Journal of Colloid and Interface Science. 663, p. 449-457

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5

    Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cellular effects and delivery propensity of penetratin is influenced by conjugation to parathyroid hormone fragment 1-34 in synergy with pH

    Kristensen, Mie, Nielsen, L. H., Zor, K., Boisen, A., Christensen, M. V., Berthelsen, J. & Nielsen, Hanne Mørck, 2018, In: Bioconjugate Chemistry. 29, 2, p. 371-381

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Peptide-enhanced oral delivery of therapeutic peptides and proteins

    Kristensen, M., Foged, C., Berthelsen, J. & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 365-373 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Characterization of PTH-CPP fusion peptides for oral delivery

    Kristensen, Mie, Berthelsen, J. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  33. Published

    Cell-Penetrating Peptides as Carriers for Oral Delivery of Biopharmaceuticals

    Kristensen, Mie & Nielsen, Hanne Mørck, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology Online. 118, 2, p. 99-106 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers

    Kristensen, Mie & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  35. Published

    Increased Carrier Peptide Stability through pH Adjustment Improves Insulin and PTH(1-34) Delivery In Vitro and In Vivo Rather than by Enforced Carrier Peptide-Cargo Complexation

    Kristensen, Mie, Diedrichsen, Ragna Guldsmed, Vetri, V., Foderà, Vito & Nielsen, Hanne Mørck, 2020, In: Pharmaceutics. 12, 10, 18 p., 993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Peptide-enhanced oral delivery of therapeutic peptides and proteins

    Kristensen, Mie, Foged, Camilla, Berthelsen, J. & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 365-373 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Carrier peptide-mediated transepithelial permeation of biopharmaceuticals: Effect of co-administration versus direct conjugation

    Kristensen, Mie & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  38. Published

    Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation

    Kristensen, Mie, de Groot, A. M., Berthelsen, J., Franzyk, Henrik, Sijts, A. & Nielsen, Hanne Mørck, 18 Mar 2015, In: Bioconjugate Chemistry. 26, p. 477-488 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

    Kristensen, M., Franzyk, H., Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, V. & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Cell-penetrating peptides as tools to enhance non-injectable delivery of biopharmaceuticals

    Kristensen, Mie & Nielsen, Hanne Mørck, 2016, In: Tissue Barriers. 4, 2, 15 p., e1178369.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Penetratin-mediated transepithelial insulin pemeation: Importance of complexation?

    Kristensen, Mie, Foderà, Vito & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  42. Published

    Parathyroid hormone coupled to cell-penetrating peptides for oral delivery

    Kristensen, Mie & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  43. Published

    Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

    Kristensen, Mie, Franzyk, Henrik, Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, Vito & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers

    Kristensen, M. & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  45. Published

    Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein Cargos

    Kristensen, Mie, Birch, D. & Nielsen, Hanne Mørck, 30 Jan 2016, In: International Journal of Molecular Sciences . 17, 2, p. 1-17 17 p., 185.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches

    Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, 9 Oct 2016, In: International Journal of Molecular Sciences . 17, 10, 19 p., 1688.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Combining diagnostic methods for antimicrobial susceptibility testing – A comparative approach

    Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, Jan 2018, In: Journal of Microbiological Methods. 144, p. 177-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    On the temperature dependence of complex formation between chitosan and proteins

    Kasimova, M. R., Valázquez-Campoy, A. & Nielsen, Hanne Mørck, 2011, In: Biomacromolecules. 12, 7, p. 2534-2543

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. On the temperature dependence of complex formation between chitosan and proteins

    Kasimova, M. R., Valázquez-Campoy, A. & Nielsen, Hanne Mørck, 2011, In: Biomacromolecules. 12, 7, p. 2534-2543

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines

    Jørgensen, Lene & Nielsen, Hanne Mørck, 2009, Wiley. 413 p.

    Research output: Book/Report › Book › Research › peer-review

  52. Published

    Issues in development of biodrug delivery systems

    Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  53. Published

    Biotechnology-based pharmaceuticals

    Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  54. Biotechnology-based pharmaceuticals

    Jørgensen, L., Nielsen, Hanne Mørck & Frøkjær, S., 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  55. Published

    Issues in Development of Biodrug Delivery Systems

    Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  56. Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines

    Jørgensen, L. & Nielsen, Hanne Mørck, 2009, Wiley. 413 p.

    Research output: Book/Report › Book › Research › peer-review

  57. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Design of a self-unfolding delivery concept for oral administration of macromolecules

    Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Cellular and intracellular distribution of recombinant activated factor VII in the rat liver

    Johansen, T. S., Nielsen, Hanne Mørck, Christensen, E. I. & Appa, R. S., 2010, In: Thrombosis and Haemostasis. 103, 4, p. 860-862

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes

    Johansen, T. S., Nielsen, Hanne Mørck, Christensen, E. I. & Appa, R. S., 2010, In: Thrombosis and Haemostasis. 104, 6, p. 1166-1173

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes

    Johansen, T. S., Nielsen, Hanne Mørck, Christensen, E. I. & Appa, R. S., 2010, In: Thrombosis and Haemostasis. 104, 6, p. 1166-1173

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver

    Johansen, T. S., Appa, R. S., Christensen, E. I., Ioannou, Y. A., Krogh, T. N., Karpf, D. M. & Nielsen, Hanne Mørck, 2011, In: Thrombosis Research. 127, 4, p. 356-362

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver

    Johansen, T. S., Appa, R. S., Christensen, E. I., Ioannou, Y. A., Krogh, T. N., Karpf, D. M. & Nielsen, Hanne Mørck, 2011, In: Thrombosis Research. 127, 4, p. 356-362

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Cellular and intracellular distribution of recombinant activated factor VII in the rat liver

    Johansen, T. S., Nielsen, Hanne Mørck, Christensen, E. I. & Appa, R. S., 2010, In: Thrombosis and Haemostasis. 103, 4, p. 860-862

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Delivery of siRNA Complexed with Palmitoylated α-Peptide/β-Peptoid Cell-Penetrating Peptidomimetics: Membrane Interaction and Structural Characterization of a Lipid-Based Nanocarrier System.

    Jing, X., Foged, Camilla, Martin-Bertelsen, Birte, Yaghmur, Anan, Knapp, K. M., Malmsten, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 6 Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 1739-1749 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

    Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

    Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

    Research output: Contribution to journal › Conference abstract in journal › Research

  68. Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

    Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, H., Foged, C. & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

    Research output: Contribution to journal › Conference abstract in journal › Research

  69. Published

    Kan nanopartikler bruges i behandlingen af hudsygdomme?

    Jensen, L. B., Knudsen, N. Ø., Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Lægemiddelforskning. 2010, p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  70. Kan nanopartikler bruges i behandlingen af hudsygdomme?

    Jensen, L. B., Knudsen, N. Ø., Foged, C. & Nielsen, Hanne Mørck, 2010, In: Lægemiddelforskning. 2010, p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  71. Published

    Corticosteroid solubility and lilpid polarity control release from solid lipid nanoparticles

    Jensen, L. B., Magnusson, E., Gunnarsson, L., Vermehren, C., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 53-60

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations

    Jensen, L. B., Mortensen, K., Pavan, G. M., Kasimova, M. R., Jensen, D. K., Gadzhyeva, V., Nielsen, Hanne Mørck & Foged, C., 2010, In: Biomacromolecules. 11, 12, p. 3571-3577

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression

    Jensen, L. B., Griger, J., Naeye, B., Varkouhi, A. K., Raemdonck, K., Schiffelers, R., Lammers, T., Storm, G., Smedt, S. C. D., Sproat, B. S., Nielsen, Hanne Mørck & Foged, Camilla, 2012, In: Pharmaceutical Research. 29, p. 669-682

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin

    Jensen, L. B., Nielsen, Hanne Mørck & Foged, Camilla, 2008, In: Lægemiddelforskning. p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  75. Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles

    Jensen, L. B., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Journal of Pharmacy and Pharmacology. p. 793-794

    Research output: Contribution to journal › Conference abstract in journal › Research

  76. Published

    Elucidating the molecular mechanism of PAMAM-siRNA dendriplex self-assembly: Effect of dendrimer charge density

    Jensen, L. B., Pavan, G. M., Kasimova, M. R., Rutherford, S., Danani, A., Nielsen, Hanne Mørck & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, 2, p. 410-418

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    In vitro penetration properties of solid lipid nanoparticles in intact and barrier-impaired skin

    Jensen, L. B., Petersson, K. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 79, 1, p. 68-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles

    Jensen, L. B., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Journal of Pharmacy and Pharmacology. p. 793-794

    Research output: Contribution to journal › Conference abstract in journal › Research

  79. Dendritiske nanostrukturer som transportører af genestisk medicin

    Jensen, L. B., Nielsen, Hanne Mørck & Foged, C., 2008, In: Lægemiddelforskning. p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  80. Published

    Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations

    Jensen, L. B., Mortensen, Kell, Pavan, G. M., Kasimova, M. R., Jensen, D. K., Gadzhyeva, V., Nielsen, Hanne Mørck & Foged, Camilla, 2010, In: Biomacromolecules. 11, 12, p. 3571-3577

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Molecular Characterization of the Interaction between siRNA and PAMAM G7 Dendrimers by SAXS, ITC, and Molecular Dynamics Simulations

    Jensen, L. B., Mortensen, Kell, Pavan, G. M., Kasimova, M. R., Jensen, D. K., Gadzhyeva, V., Nielsen, Hanne Mørck & Foged, Camilla, Dec 2010, In: Biomacromolecules. 11, 12, p. 3571-3577

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation

    Jensen, D. M. K., Cun, D., Maltesen, M. J., Frøkjær, Sven, Nielsen, Hanne Mørck & Foged, Camilla, 2010, In: Journal of Controlled Release. 142, p. 138-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA

    Jensen, D. M. K., Jensen, L. B., Koocheki, S., Cun, D., Nielsen, Hanne Mørck, Foged, Camilla & Bengtson, L., 2012, In: Journal of Controlled Release. 157, 1, p. 141-148

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation

    Jensen, D. M. K., Cun, D., Maltesen, M. J., Frøkjær, S., Nielsen, Hanne Mørck & Foged, C., 2010, In: Journal of Controlled Release. 142, p. 138-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

    Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    End Group Modification: Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria

    Jahnsen, R. O., Sandberg-Schaal, A., Frimodt-Møller, N., Nielsen, Hanne Mørck & Franzyk, Henrik, 23 Jan 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 95, Part A, p. 40–46 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

    Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Stabilization of liposomes during drying

    Ingvarsson, P. Þ., Yang, M., Nielsen, Hanne Mørck, Rantanen, J. T. & Foged, C., 2011, In: Expert Opinion on Drug Delivery. 8, 3, p. 375-388

    Research output: Contribution to journal › Review › Research

  89. Published

    Stabilization of liposomes during drying

    Ingvarsson, P. Þ., Yang, Mingshi, Nielsen, Hanne Mørck, Rantanen, Jukka & Foged, Camilla, 2011, In: Expert Opinion on Drug Delivery. 8, 3, p. 375-388

    Research output: Contribution to journal › Review › Research

  90. Published

    Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01

    Ingvarsson, P. T., Schmidt, S. T., Christensen, D., Larsen, N. B., Hinrichs, W. L. J., Andersen, P., Rantanen, Jukka, Nielsen, Hanne Mørck, Yang, Mingshi & Foged, Camilla, 8 Feb 2013, In: Journal of Controlled Release. 167, 3, p. 256-264

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process

    Ingvarsson, P. T., Yang, Mingshi, Mulvad, H., Nielsen, Hanne Mørck, Rantanen, Jukka & Foged, Camilla, 22 Jun 2013, In: Pharmaceutical Research. 30, 11, p. 2772-2784

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin

    Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Synthesis of carbon quantum dot-poly lactic-co-glycolic acid hybrid nanoparticles for chemo-photothermal therapy against bacterial biofilms

    Huang, Z., Zhou, T., Yuan, Y., Klodziska, S. N., Zheng, T., Sternberg, C., Nielsen, Hanne Mørck, Sun, Y. & Wan, F., 2020, In: Journal of Colloid and Interface Science. 577, p. 66-74 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections

    Huang, Z., Klodzinska, S. N., Wan, F. & Nielsen, Hanne Mørck, 2021, In: Drug Delivery and Translational Research. 11, p. 1634–1654

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

    Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Drug delivery studies in Caco-2 monolayers. II. Absorption enhancer effects of lysophosphatidylcholines

    Hovgaard, L., Brøndsted, H. & Nielsen, Hanne Mørck, 14 Feb 1995, In: International Journal of Pharmaceutics. 114, 2, p. 141-149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

    Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Shuffled lipidation pattern and degree of lipidation determines the membrane interaction behavior of a linear cationic membrane-active peptide

    Hedegaard, S. F., Bruhn, D. S., Khandelia, H., Cardenas, M. & Nielsen, Hanne Mørck, 2020, In: Journal of Colloid and Interface Science. 578, p. 584-597 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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