Engineering of an Inhalable DDA/TDB Liposomal Adjuvant: A Quality-by-Design Approach Towards Optimization of the Spray Drying Process

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The purpose of this study was to identify and optimize spray drying parameters of importance for the design of an inhalable powder formulation of a cationic liposomal adjuvant composed of dimethyldioctadecylammonium (DDA) bromide and trehalose-6,6'-dibehenate (TDB).
Original languageEnglish
JournalPharmaceutical Research
Issue number11
Pages (from-to)2772-2784
Publication statusPublished - 22 Jun 2013

ID: 49284131