Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
Introductory remarks on publicationslist
Publication Statistics
(data until September 2020)
Books 3 Book chapters 17 Int. peer reviewed journal articles 450
Professional journal articles 32
Conference contributions >700
Patents 13
H Index (Google Scholar) 76
Total number of citations (Google Scholar) 20346
- 2019
- Published
Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures
Kissi, E. O., Khorami, Keyoomars & Rades, Thomas, 2019, In: Pharmaceutics. 11, 11 p., 628.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Difficulties of Subsurface Liquid Front Tracking in Porous Media with Terahertz Pulsed Imaging
Al-Sharabi, M., Mudley, T., Markl, D., Bawuah, P., Karttunen, A. P., Ridgway, C. J., Gane, P. A. C., Ketolainen, J., Peiponen, K. E., Rades, Thomas & Zeitler, J. A., 2019, 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves. IEEE, 8874143. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, Vol. 2019-September).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy
Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the effects of spray drying parameters for producing cubosome powder precursors
von Halling Laier, C., Sonne Alstrøm, T., Travers Bargholz, M., Bjerg Sjøltov, P., Rades, Thomas, Boisen, A. & Nielsen, L. H., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 135, p. 44-48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5
Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency Raman Spectroscopic Study on Compression-Induced Destabilization in Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2019, In: Molecular Pharmaceutics. 16, 8, p. 3678-3686 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica
Hoefer, H. H., Monsuur, F. H., Pauly, T., Choudhari, Y., Löbmann, Korbinian & Rades, Thomas, 2019, Patent No. US20190350855A1Research output: Patent
- Published
Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation
von Halling Laier, C., Gibson, B., Moreno, J. A. S., Rades, Thomas, Hook, S., Nielsen, L. H. & Boisen, A., 2019, In: Journal of Controlled Release. 294, p. 91-101 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-aqueous topical compositions comprising a halogenated salicylanilide
Sommer, M., Li, P., Frandsen, C. H., Nielsen, Hanne Mørck, Priemel, P. A. & Rades, Thomas, 2019, Patent No. US20190151231A1Research output: Patent
- Published
Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations
Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, Thomas & Groenning, M., 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology
Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Solid State Characterization of Ciprofloxacin Liposome Nanocrystals
Li, T., Mudie, S., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Molecular Pharmaceutics. 16, 1, p. 184-194 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spectroscopic Evidence of Tertiary Structural Differences Between Insulin Molecules in Fibrils
Schack, M. M., Dahl, K., Rades, Thomas, Groenning, M. & Carpenter, J. F., 2019, In: Journal of Pharmaceutical Sciences. 108, 9, p. 2871-2879Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201Research output: Contribution to journal › Letter › Research › peer-review
- Published
Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptides as co-formers in co-amorphous systems
Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions
Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems
Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes
Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imaging of dehydration in particulate matter using Raman line-focus microscopy
Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
- Published
Direct Measurement of Amorphous Solubility
Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering
Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles
Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis
Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures
Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.Research output: Contribution to journal › Journal article › Communication
- 2020
- Published
Amino acids as stabilizers for spray-dried simvastatin powder for inhalation
Lu, W., Rades, Thomas, Rantanen, Jukka, Chan, H. & Yang, Mingshi, 2020, In: International Journal of Pharmaceutics. 572, 12 p., 118724.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing
Öblom, H., Cornett, Claus, Bøtker, Johan Peter, Frøkjær, Sven, Hansen, Harald S., Rades, Thomas, Rantanen, Jukka & Genina, Natalja, 2020, In: International Journal of Pharmaceutics. 589, p. 1-11 119866.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of the Optimal Molar Ratio in Amino Acid-Based Coamorphous Systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2020, In: Molecular Pharmaceutics. 17, 4, p. 1335-1342 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Measurement of Lateral Molecular Diffusivity on the Surface of Supersaturated Amorphous Solid Dispersions by Atomic Force Microscopy
Bannow, J., Karl, M., Larsen, P. E., Hwu, E. T. & Rades, Thomas, 2020, In: Molecular Pharmaceutics. 17, 5, p. 1715-1722 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure of liposomes containing nanocrystallised ciprofloxacin to digestive media induces solid-state transformation and altered in vitro drug release
Li, T., Hawley, A., Rades, Thomas & Boyd, B. J., 2020, In: Journal of Controlled Release. 323, p. 350-360 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functionalised calcium carbonate as a coformer to stabilize amorphous drugs by mechanochemical activation
Liu, J., Rades, Thomas, Tho, I. & Kissi, E. O., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 155, p. 22-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Highly Elastic and Water Stable Zein Microfibers as a Potential Drug Delivery System for Wound Healing
Akhmetova, A., Lanno, G., Kogermann, K., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2020, In: Pharmaceutics. 12, 5, 19 p., 458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hot Melt Coating of Amorphous Carvedilol
Bannow, J., Koren, L., Salar-Behzadi, S., Löbmann, Korbinian, Zimmer, A. & Rades, Thomas, 2020, In: Pharmaceutics. 12, 6, 13 p., 519.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors
Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems
Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous investigation of the liquid transport and swelling performance during tablet disintegration
Al-Sharabi, M., Markl, D., Mudley, T., Bawuah, P., Karttunen, A., Ridgway, C., Gane, P., Ketolainen, J., Peiponen, K., Rades, Thomas & Zeitler, J. A., 2020, In: International Journal of Pharmaceutics. 584, 11 p., 119380.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single particles as resonators for thermomechanical analysis
Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solving the Computational Puzzle: Toward a Pragmatic Pathway for Modeling Low-Energy Vibrational Modes of Pharmaceutical Crystals
Bērziņš, Kārlis, Sutton, J. J., Fraser-Miller, S. J., Rades, Thomas, Korter, T. M. & Gordon, K. C., 2020, In: Crystal Growth & Design. 20, 10, p. 6947-6955Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition
Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems
Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: pH shift versus solvent shift
Plum, J., Bavnhoj, C., Palmelund, H., Perez-Alos, L., Mullertz, Anette & Rades, Thomas, 5 Jan 2020, In: International Journal of Pharmaceutics. 573, 8 p., 118862.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin
Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Poorly soluble drugs
Siepmann, J., Rades, Thomas, Mullertz, Anette & Loftsson, T., 15 Mar 2020, In: International Journal of Pharmaceutics. 577, 119055.Research output: Contribution to journal › Editorial › Research
- Published
Effect of supersaturation on absorption of indomethacin and tadalafil in a single pass intestinal perfusion rat model, in the absence and presence of a precipitation inhibitor
Strindberg, S., Plum, J., Stie, Mai Bay, Christiansen, M. L., Nielsen, L. H., Rades, Thomas & Mullertz, Anette , Jun 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A Multivariate Approach for the Determination of the Optimal Mixing Ratio of the Non-Strong Interacting Co-Amorphous System Carvedilol-Tryptophan
Di, Rong, Liu, J., Grohganz, Holger & Rades, Thomas, 2021, In: Molecules. 26, 4, 8 p., 801.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.Research output: Contribution to journal › Review › Research
- Published
Combined Effect of the Preparation Method and Compression on the Physical Stability and Dissolution Behavior of Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Di, Rong, Liu, J., Peltonen, L., Strachan, C. J., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1408-1418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers
Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and optimization of self-nanoemulsifying drug delivery systems of clove oil for efficacy enhancement in fish anesthesia
Kheawfu, Pikulkaew, Rades, Thomas, Mullertz, Anette , Jørgensen, Louise von Gersdorff & Okonogi, 2021, In: Journal of Drug Delivery Science and Technology. 61, 9 p., 102241.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of a self-unfolding delivery concept for oral administration of macromolecules
Jørgensen, J. R., Thamdrup, L. H. E., Kamguyan, K., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 2021, In: Journal of Controlled Release. 329, p. 948-954Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Self-Nanoemulsifying Drug Delivery Systems Containing 4-Allylpyrocatechol for Treatment of Oral Infections Caused by Candida albicans
Okonogi, S., Phumat, P., Khongkhunthian, S., Chaijareenont, P., Rades, Thomas & Mullertz, Anette , 2021, In: Pharmaceutics. 13, 2, 16 p., 167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol
Madsen, C. M., Plum, J., Hens, B., Augustijns, P., Mullertz, Anette & Rades, Thomas, 2021, In: Journal of Pharmaceutical Sciences. 110, 6, p. 2479-2488 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation optimization, anesthetic activity, skin permeation, and transportation pathway of Alpinia galanga oil SNEDDS in zebrafish (Danio rerio)
Khumpirapang, N., Jørgensen, Louise von Gersdorff, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 165, p. 193-202 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking
Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating to Optimal Ratio between Drug and Co-Former in Co-Amorphous Systems
Rades, Thomas, 2021, In: Proceedings. 78, 1, 1 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation on Formulation Strategies to Mitigate Compression-Induced Destabilization in Supersaturated Celecoxib Amorphous Solid Dispersions
Bērziņš, Kārlis, Fraser-Miller, S. J., Walker, G. F., Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 10, p. 3882–3893Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring the Isothermal Dehydration of Crystalline Hydrates Using Low-Frequency Raman Spectroscopy
Robert, C., Fraser-Miller, S. J., Bērziņš, Kārlis, Okeyo, P. O., Rantanen, Jukka, Rades, Thomas & Gordon, K. C., 2021, In: Molecular Pharmaceutics. 18, 3, p. 1264-1276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive identification of co-formers in co-amorphous systems
Chambers, L. I., Grohganz, Holger, Palmelund, H., Löbmann, Korbinian, Rades, Thomas, Musa, O. M. & Steed, J. W., 2021, In: European Journal of Pharmaceutical Sciences. 157, 9 p., 105636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probabilistic modeling of an injectable aqueous crystalline suspension using influence networks
Sekulovic, A., Petit, M., Verrijk, R., Rades, Thomas & Rantanen, Jukka, 2021, In: International Journal of Pharmaceutics. 596, 11 p., 120283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous automated image analysis and Raman spectroscopy of powders at an individual particle level
Sekulovic, A., Verrijk, R., Rades, Thomas, Grabarek, A., Jiskoot, W., Hawe, A. & Rantanen, Jukka, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 193, 8 p., 113744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of moisture on the storage stability of co-amorphous systems
Liu, J., Rades, Thomas & Grohganz, Holger, 2021, In: International Journal of Pharmaceutics. 605, 120802.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray Imaging for Gastrointestinal Tracking of Microscale Oral Drug Delivery Devices
Kjeldsen, R. B., Kristensen, M. N., Gundlach, C., Thamdrup, L. H. E., Mullertz, Anette , Rades, Thomas, Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: ACS Biomaterials Science and Engineering. 7, 6, p. 2538–2547Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
(Co-)amorphization of enantiomers – Investigation of the amorphization process, the physical stability and the dissolution behavior
Holzapfel, K., Liu, J., Rades, Thomas & Leopold, C. S., 2022, In: International Journal of Pharmaceutics. 616, 9 p., 121552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new method to determine drug-polymer solubility through enthalpy of melting and mixing
Meiland, Peter, Larsen, B. S., Knopp, Matthias Manne, Tho, I. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 629, 9 p., 122391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Additive manufacturing in respiratory sciences – Current applications and future prospects
Bock, S., Rades, Thomas, Rantanen, Jukka & Scherließ, R., 2022, In: Advanced Drug Delivery Reviews. 186, 14 p., 114341.Research output: Contribution to journal › Review › Research › peer-review
- Published
Combining lipid based drug delivery and amorphous solid dispersions for improved oral drug absorption of a poorly water-soluble drug
Nora, G., Venkatasubramanian, R., Strindberg, S., Siqueira-Jørgensen, S. D., Pagano, L., Romanski, F. S., Swarnakar, N. K., Rades, Thomas & Mullertz, Anette , 2022, In: Journal of Controlled Release. 349, p. 206-212Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a Microgram Scale Video-Microscopic Method to Investigate Dissolution Behavior of Poorly Water-Soluble Drugs
Senniksen, M. B., Christfort, J. F., Marabini, R., Spillum, E., Matthews, W., Da Vià, L., Plum, J., Rades, Thomas & Mullertz, Anette , 2022, In: AAPS PharmSciTech. 23, 6, 173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of polymer addition on the non-strongly interacting binary co-amorphous system carvedilol-tryptophan
Wang, Y., Grohganz, Holger & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 617, 9 p., 121625.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating Pathway and Anesthetic Mechanism of Action of Clove Oil Nanoformulations in Fish
Kheawfu, K., Pikulkaew, S., Wellendorph, Petrine, Jørgensen, Louise von Gersdorff, Rades, Thomas, Mullertz, Anette & Okonogi, S., 2022, In: Pharmaceutics. 14, 5, 13 p., 919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the Dehydration Mechanism of Nitrofurantoin Monohydrate II Using Low-Frequency Raman Spectroscopy
Remoto, P. J. G., Bērziņš, Kārlis, Fraser-Miller, S. J., Korter, T. M., Rades, Thomas, Rantanen, Jukka & Gordon, K. C., 2022, In: Crystal Growth and Design. 22, 4, p. 2733-2741Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems
Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of oral gavage technique of drug-containing microcontainers on the gastrointestinal transit and absorption in rats
Kristensen, M. N., Rades, Thomas, Boisen, A. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 618, 121630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Situ Transformation of Electrospun Nanofibers into Nanofiber-Reinforced Hydrogels
Martin, A., Nyman, J. N., Reinholdt, R., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: Nanomaterials. 12, 14, 2437.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Water on Amorphous Lidocaine
Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency Raman Spectroscopy as an Avenue to Determine the Transition Temperature of β- and γ-Relaxation in Pharmaceutical Glasses
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2022, In: Analytical Chemistry. 94, 23, p. 8241-8248Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmaceutical Technology in Europe
Siepmann, J., Basit, A. & Rades, Thomas, 2022, In: International Journal of Pharmaceutics. 613, 1 p., 121441.Research output: Contribution to journal › Editorial › Research
- Published
Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine
Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of multiple RNA cargoes co-loaded into nanoparticle-based delivery systems
Lokras, Abhijeet, Chakravarty, A., Rades, Thomas, Christensen, D., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 626, 13 p., 122171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part I; feasibility study using indomethacin
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 147-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solventless amorphization and pelletization using a high shear granulator. Part II; Preparation of co-amorphous mixture-layered pellets using indomethacin and arginine
Kondo, K. & Rades, Thomas, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 181, p. 183-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform
Khumpirapang, N., Suknuntha, K., Wongrattanakamon, P., Jiranusornkul, S., Anuchapreeda, S., Wellendorph, Petrine, Mullertz, Anette , Rades, Thomas & Okonogi, S., 2022, In: Pharmaceutics. 14, 3, 15 p., 650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial
Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, , 2022, In: Clinical and Translational Medicine. 12, 5, e790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zein-polycaprolactone core-shell nanofibers for wound healing
Martin, A., Cai, Jun, Gürtler, Anna-Lena, van der Plas, Mariena J.A., Malmsten, Martin, Rades, Thomas & Heinz, Andrea, 2022, In: International Journal of Pharmaceutics. 621, 10 p., 121809.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
In vitro-in vivo relationship for amorphous solid dispersions using a double membrane dissolution-permeation setup
Jørgensen, J. R., Mohr, W., Rischer, M., Sauer, A., Mistry, S., Rades, Thomas & Mullertz, Anette , 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 188, p. 26-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphization of different furosemide polymorphic forms during ball milling: Tracking solid-to-solid phase transformations
Wang, M., Gong, J., Rades, Thomas & Batista Martins, Inês Catarina, 2023, In: International Journal of Pharmaceutics. 648, 9 p., 123573.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids
Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-amorphous systems consisting of indomethacin and the chiral co-former tryptophan: Solid-state properties and molecular mobilities
Holzapfel, K., Rades, Thomas & Leopold, C. S., 2023, In: International Journal of Pharmaceutics. 636, 12 p., 122840.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38132533
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
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