Lene Jørgensen
Associate Professor
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Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276Research output: Contribution to journal › Journal article › Research › peer-review
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Simple measurements for prediction of drug release from polymer matrices - Solubility parameters and intrinsic viscosity
Madsen, C. G., Skov, A., Baldursdottir, S., Rades, Thomas, Jørgensen, Lene & Medlicott, N. J., 7 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of mixed solvents on polymer conformation –correlation between the Hildebrand/Hansen solubility parameters and the intrinsic viscosity of polymer solutions
Madsen, C. G., Skov, A., Jørgensen, Lene, Baldursdottir, S. G. & Medlicott, N., 2013, In: Nordic Rheology Society Annual Transactions. 21, p. 354-352Research output: Contribution to journal › Conference article › Research
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Responsive gelation of hydrophobized linear polymer
Madsen, C. G., Toeth, J., Jørgensen, Lene, Hietala, S., Baldursdottir, S. G. & Hietala, S., 2014. 4 p.Research output: Contribution to conference › Paper › Research
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Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme
Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring the chemical space for freeze-drying excipients
Meng-Lund, H., Holm, T. P., Poso, A., Jørgensen, Lene, Rantanen, Jukka & Grohganz, Holger, 2019, In: International Journal of Pharmaceutics. 566, p. 254-263 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains
Mohd Hidzir, N., Anitha, A., Kepa, K., Hill, D. J. T., Jørgensen, Lene & Grondahl, L., 2020, In: Biointerphases. 15, 3, 11 p., 031011.Research output: Contribution to journal › Journal article › Research › peer-review
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Interfacial adsorption of insulin - conformational changes and reversibility of adsorption
Mollmann, S. H., Jørgensen, Lene, Bukrinsky, J. T., Elofsson, U., Norde, W. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, p. 194-204Research output: Contribution to journal › Journal article › Research › peer-review
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Protein nanopharmaceuticals - concepts and safety considerations
Møller, E. H., Jørgensen, Lene & Medlicott, N. J., 2013, Nanopharmaceutics: the potential application of nanomaterials. Liang, X-J. (ed.). Singapore: World Scientific, p. 49-Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Alternative routes of administration for systemic delivery of protein pharmaceuticals
Møller, E. H. & Jørgensen, Lene, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 89-94Research output: Contribution to journal › Journal article › Research › peer-review
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Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems
Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Biologiske lægemidler - fra molekyle til medicin
Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14Research output: Contribution to journal › Journal article › Research
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Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo
Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
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A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes
Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.Research output: Contribution to journal › Journal article › Research
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Towards the understanding of complex fluids in pharmaceutical sciences
Pedersen, P. B., Pekka Pajander, J., Mullertz, Anette , Vilmann, Peter, Jørgensen, Lene & Baldursdottir, S. G., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 393 401 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metode til screening af modificerede proteinlægemidler under opbevaring
Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18Research output: Contribution to journal › Journal article › Communication
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Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces
Pinholt, C., Kapp, S. J., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2013, In: International Journal of Pharmaceutics. 440, 1, p. 63-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces
Pinholt, C., Bukrinsky, J. T., Hostrup, S., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 139-147Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces
Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In: European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?
Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of acylation on the adsorption of insulin to hydrophobic surfaces
Pinholt, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven & Jørgensen, Lene, 2011, In: Pharmaceutical Research. 28, p. 1031-1040Research output: Contribution to journal › Journal article › Research › peer-review
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Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles
Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17Research output: Contribution to journal › Journal article › Research › peer-review
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Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation technologies to overcome unfavorable properties of peptides and proteins for pulmonary delivery
Wan, F., Møller, E. H., Yang, Mingshi & Jørgensen, Lene, 2012, In: Drug Discovery Today: Technologies. 9, 2, p. e141-e146Research output: Contribution to journal › Journal article › Research › peer-review
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Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability
Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration
Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In: Biomacromolecules. 13, p. 905-917Research output: Contribution to journal › Journal article › Research › peer-review
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Development of biodegradable nanocomposite scaffolds for autologous cell therapy
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 1 Jan 2011, In: European Cells and Materials. 21, SUPPL.1, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Everland, H., Møller, E. H. & Nielsen, Hanne Mørck, 2011, In: Journal of Controlled Release. 156, 1, p. 11-20Research output: Contribution to journal › Journal article › Research › peer-review
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Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs
Wen, Y., Gallego, M. R., Nielsen, L. F., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, Sep 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 1, p. 87-98 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation on Secondary Structure Perturbations of Proteins Embedded in Solid Lipid Matrices as a Novel Indicator of their Biological Activity upon In Vitro Release
Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 1 Feb 2018, In: AAPS PharmSciTech. 19, 2, p. 769–782Research output: Contribution to journal › Journal article › Research › peer-review
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Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopy as an Analytical Method to Investigate the Secondary Structure of a Model Protein Embedded in Solid Lipid Matrices
Zeeshan, F., Tabbassum, M., Jørgensen, Lene & Medlicott, N. J., 2018, In: Applied Spectroscopy. 72, 2, p. 268-279 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Infrared spectroscopy to characterize protein aggregates
van de Weert, Marco & Jørgensen, Lene, 2012, Analysis of aggregates and particles in protein pharmaceuticals. Mahler, H-C. & Jiskoot, W. (eds.). Hoboken: Wiley, p. 227-248Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Infrared spectroscopy of protein pharmaceuticals
van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Factors of importance for a successful delivery system for proteins
van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar
Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29Research output: Contribution to journal › Journal article › Research
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Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis
Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299770
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Proteiner i lægemidler - de sætter sig alle de forkerte steder
Research output: Contribution to journal › Journal article › Research
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Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
Research output: Contribution to journal › Journal article › Research › peer-review
Published