Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Epithelial permeation and absorption mechanisms of biopharmaceuticals

    Nielsen, Hanne Mørck, 1 Oct 2014, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies. Springer US, Vol. 9781461495246. p. 99-122 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  2. Published

    Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison

    Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Evaluation of carrier-mediated siRNA delivery: lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA

    Colombo, S., Nielsen, Hanne Mørck & Foged, Camilla, 11 Jan 2013, In: Journal of Controlled Release. 166, 3, p. 220-226 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate

    Eirheim, H. U., Bundgaard, C. & Nielsen, Hanne Mørck, 2004, In: Toxicology in Vitro. 18, 5, p. 649-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Evaluation of drug permeation under fed state conditions using mucus-covered Caco-2 cell epithelium

    Birch, D., Diedrichsen, Ragna Guldsmed, Christophersen, P. C., Mu, Huiling & Nielsen, Hanne Mørck, Jun 2018, In: European Journal of Pharmaceutical Sciences. 118, p. 144-153

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

    Rønholt, Stine, Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, Hanne Mørck, 1 Jan 2019, In: Drug Delivery. 26, 1, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Farvel til sprøjten: udvikling af vaccineplaster med nanopartikler

    Madsen, H. B., Ifversen, P., Madsen, F., Manniche, S. & Nielsen, Hanne Mørck, 2007, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journal › Journal article › Communication

  8. Farvel til sprøjten: udvikling af vaccineplaster med nanopartikler

    Madsen, H. B., Ifversen, P., Madsen, F., Manniche, S. & Nielsen, Hanne Mørck, 2007, In: Lægemiddelforskning. p. 12-13

    Research output: Contribution to journal › Journal article › Communication

  9. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

    Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  12. Published

    Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  13. Published

    Genetisk nanomedicin til behandling af leddegigt

    Foged, Camilla, Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  14. Genetisk nanomedicin til behandling af leddegigt

    Foged, C., Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  15. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy

    Zhou, X., Sinkjær, Anders Wilgaard, Zhang, Min, Pinholt, H. D., Nielsen, Hanne Mørck, Hatzakis, Nikos, van de Weert, Marco & Foderà, Vito, 2023, In: The Journal of Physical Chemistry Letters. 14, 4, p. 912-919

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, Camilla & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, C. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin

    Water, J. J., Kim, Y., Maltesen, M. J., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, Aug 2015, In: Pharmaceutical Research. 32, 8, p. 2727-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5

    Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, C., Franzyk, H. & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journal › Journal article › Research

  22. Published

    Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journal › Journal article › Research

  23. Published

    Immunity by formulation design: induction of high CD8+ T-cell responses by poly (I:C) incorporated into the CAF01 adjuvant via a double emulsion method

    Nordly, P. J., Rose, F., Christensen, D., Nielsen, Hanne Mørck, Andersen, P., Agger, E. M. & Foged, Camilla, 2011, In: Journal of Controlled Release. 150, 3, p. 307-317

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Immunogenicity Testing of Lipidoids In Vitro and In Silico: Modulating Lipidoid-Mediated TLR4 Activation by Nanoparticle Design

    de Groot, A. M., Thanki, K., Gangloff, M., Falkenberg, E., Zeng, X., van Bijnen, D. C. J., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck, Broere, F., Gay, N. J., Foged, Camilla & Sijts, A. J. A. M., 1 Jun 2018, In: Molecular Therapy - Nucleic Acids. 11, p. 159-169 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Impact of capacity-limited binding on recombinant factor VIII and von Willebrand factor pharmacokinetics in hemophilia A rats

    Vargas Christensen, I., Loftager, M., Rode, F., Nielsen, Hanne Mørck, Kreilgaard, M. & Larsen, M. S., 2019, In: Journal of Thrombosis and Haemostasis. 17, 6, p. 964-974 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers

    Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

    Water, J. J., Maltesen, M. J., Foged, C., Franzyk, H. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  29. Published

    Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

    Water, J. J., Maltesen, M. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  30. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

    Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, Hanne Mørck, Damborg, Peter Panduro & Hansen, Paul Robert, 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

    Jørgensen, J. R., Yu, F., Ramakrishnan, V., Nielsen, L. H., Nielsen, Hanne Mørck, Boisen, A., Rades, Thomas & Mullertz, Anette , 7 Jan 2020, In: Pharmaceutics. 12, 1, 14 p., 48.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    In vitro placental model optimization for nanoparticle transport studies

    Cartwright, L., Poulsen, M. S., Nielsen, Hanne Mørck, Pojana, G., Knudsen, Lisbeth E., Saunders, M. & Rytting, E., 2012, In: International Journal of Nanomedicine (Print). 7, p. 497-510 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    In vitro placental model optimization for nanoparticle transport studies

    Cartwright, L., Poulsen, M. S., Nielsen, Hanne Mørck, Pojana, G., Knudsen, Lisbeth E., Saunders, M. & Rytting, E., 2012, In: International Journal of Nanomedicine (Online). 7, p. 497-510

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver

    Johansen, T. S., Appa, R. S., Christensen, E. I., Ioannou, Y. A., Krogh, T. N., Karpf, D. M. & Nielsen, Hanne Mørck, 2011, In: Thrombosis Research. 127, 4, p. 356-362

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    In vivo clearance and metabolism of recombinant activated factor VII (rFVIIa) and its complexes with plasma protease inhibitors in the liver

    Johansen, T. S., Appa, R. S., Christensen, E. I., Ioannou, Y. A., Krogh, T. N., Karpf, D. M. & Nielsen, Hanne Mørck, 2011, In: Thrombosis Research. 127, 4, p. 356-362

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

    Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Incorporation of the TLR4 agonist monophosphoryl lipid A into the bilayer of DDA/DTDB liposomes : physico-chemical characterization and induction of CD8+ T-Cell responses in vivo

    Nordly, P. J., Agger, E. M., Andersen, P., Nielsen, Hanne Mørck & Foged, Camilla, 2011, In: Pharmaceutical Research. 28, 3, p. 553-562

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Increased Carrier Peptide Stability through pH Adjustment Improves Insulin and PTH(1-34) Delivery In Vitro and In Vivo Rather than by Enforced Carrier Peptide-Cargo Complexation

    Kristensen, Mie, Diedrichsen, Ragna Guldsmed, Vetri, V., Foderà, Vito & Nielsen, Hanne Mørck, 2020, In: Pharmaceutics. 12, 10, 18 p., 993.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles

    Jensen, L. B., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Journal of Pharmacy and Pharmacology. p. 793-794

    Research output: Contribution to journal › Conference abstract in journal › Research

  40. Published

    Influence of skin barrier on in-vitro penetration properties of solid lipid nanoparticles

    Jensen, L. B., Nielsen, Hanne Mørck & Petersson, K., 2010, In: Journal of Pharmacy and Pharmacology. p. 793-794

    Research output: Contribution to journal › Conference abstract in journal › Research

  41. Published

    Inhalable Antimicrobials for Treatment of Bacterial Biofilm-Associated Sinusitis in Cystic Fibrosis Patients: Challenges and Drug Delivery Approaches

    Klodzinska, S. N., Priemel, P. A., Rades, Thomas & Nielsen, Hanne Mørck, 9 Oct 2016, In: International Journal of Molecular Sciences . 17, 10, 19 p., 1688.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Innovative Methods and Applications in Mucoadhesion Research

    Mackie, A. R., Goycoolea, F. M., Menchicchi, B., Caramella, C. M., Saporito, F., Lee, S., Stephansen, K., Chronakis, I. S., Hiorth, M., Adamczak, M., Waldner, M., Nielsen, Hanne Mørck & Marcelloni, L., Aug 2017, In: Macromolecular Bioscience. 17, 8, 32 p., 1600534.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Innovativt nanopartikeldesign bag skræddersyede vacciner

    Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, C., 2009, In: Lægemiddelforskning. p. 19-21

    Research output: Contribution to journal › Journal article › Research

  44. Published

    Innovativt nanopartikeldesign bag skræddersyede vacciner

    Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Lægemiddelforskning. p. 19-21

    Research output: Contribution to journal › Journal article › Research

  45. Published

    Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  46. Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, D., Franzyk, H. & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  47. Published

    Interaction of Laponite with Membrane Components-Consequences for Bacterial Aggregation and Infection Confinement

    Malekkhaiat Häffner, S., Nyström, L., Browning, K. L., Nielsen, Hanne Mørck, Strömstedt, A. A., van der Plas, Mariena J.A., Schmidtchen, A. & Malmsten, Martin, 1 May 2019, In: A C S Applied Materials and Interfaces. 11, 17, p. 15389-15400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Interactions between Surfactants in Solution and Electrospun Protein Fibers: Effects on Release Behavior and Fiber Properties

    Stephansen, K., García-Díaz, M., Jessen, F., Chronakis, I. S. & Nielsen, Hanne Mørck, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 748-55 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking

    Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

    Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

    Research output: Contribution to journal › Journal article › Research › peer-review

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