Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
- 2015
- Published
A method for studies on interactions between a gold-based drug and plasma proteins based on capillary electrophoresis with inductively coupled plasma mass spectrometry detection
Nguyen, T. T. T. N., Østergaard, Jesper & Gammelgaard, Bente, 2 Sep 2015, In: Analytical and Bioanalytical Chemistry. 407, 28, p. 8497-8503 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow induced dispersion analysis rapidly quantifies proteins in human plasma samples
Poulsen, N. N., Andersen, N. Z., Østergaard, Jesper, Zhuang, G., Petersen, Nickolaj J. & Jensen, H., 7 Jul 2015, In: The Analyst. 140, 13, p. 4365-69 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of microwave oven heating for prediction of drug-excipient compatibilities and accelerated stability studies
Schou-Pedersen, A. M. V., Østergaard, Jesper, Cornett, Claus & Hansen, S. H., 15 May 2015, In: International Journal of Pharmaceutics. 485, 1-2, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulatory Effect of Human Plasma on the Internal Nanostructure and Size Characteristics of Liquid-Crystalline Nanocarriers
Mat Azmi, I. D. B., Wu, L., Wibroe, P. P., Nilsson, C., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 30 Apr 2015, In: Langmuir. 31, 18, p. 5042–49 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid
Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy
Schou-Pedersen, A. M. V., Cornett, Claus, Nyberg, N., Østergaard, Jesper & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin
Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Microenvironmental pH measurement during sodium naproxenate dissolution in acidic medium by UV/vis imaging
Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. & Lenke, J., 17 Aug 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 100, p. 290-293 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of the esterification of active pharmaceutical ingredients containing carboxylic Acid functionality in polyethylene glycol: formulation implications
Schou-Pedersen, A. M. V., Hansen, S. H., Moesgaard, B. & Østergaard, Jesper, Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2424-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure
Nilsson, C., Østergaard, Jesper, Larsen, Susan Weng, Larsen, C., Urtti, A. & Yaghmur, Anan, 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin diffusion and self-association characterized by real-time UV imaging and Taylor dispersion analysis
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 15 Apr 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 92, p. 203-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of stability constants of tauro- and glyco-conjugated bile salts with the negatively charged sulfobutylether-β-cyclodextrin: comparison of affinity capillary electrophoresis and isothermal titration calorimetry and thermodynamic analysis of the interaction
Holm, R., Østergaard, Jesper, Schönbeck, C., Jensen, H., Shi, W., Peters, G. H. & Westh, P., Apr 2014, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 78, 1-4, p. 185-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing
Østergaard, Jesper, Wu, J., Naelapää, K., Bøtker, Johan Peter, Jensen, H. & Rantanen, Jukka, Apr 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1149-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
Thing, M., Agårdh, L., Larsen, Susan Weng, Rasmussen, R., Pallesen, J., Mertz, N., Kristensen, Jesper Langgaard, Hansen, M., Østergaard, Jesper & Larsen, C. S., 2014, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4021–4029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug formulations based on self-assembled liquid crystalline nanostructures
Yaghmur, Anan, Østergaard, Jesper, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Rappolt, M., 2014, Liposomes, lipid bilayers and model membranes: From basic research to application. Pabst, G., Kucerka, N., Nieh, M-P. & Katsaras, J. (eds.). Boca Raton: CRC Press, p. 341-360Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
UV imaging for in vitro dissolution and release studies: Initial experiences
Østergaard, Jesper, Lenke, J., Jensen, S. S., Sun, Y. & Ye, F., 2014, In: Dissolution Technologies. 21, 4, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis
Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods
Sarnes, A., Østergaard, Jesper, Jensen, S. S., Aaltonen, J., Rantanen, Jukka, Hirvonen, J. & Peltonen, L., 20 Nov 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 511-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis
Zhuang, G., Poulsen, N. N., Petersen, Nickolaj J., Østergaard, Jesper & Jensen, H., 2 Sep 2013, 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. p. 1054-1057 4 p. 6559903Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication
- Published
Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging
Gaunø, M. H., Vilhelmsen, T., Larsen, C. C., Bøtker, Johan Peter, Wittendorff, J., Rantanen, Jukka & Østergaard, Jesper, Sep 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 83, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications
Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, Anan, 7 Aug 2013, In: Biomaterials. 34, 33, p. 8491-8503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat
Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of platinum drug release and liposome stability in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 5 Jun 2013, In: International Journal of Pharmaceutics. 449, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 10 May 2013, IPC No. C07D 487/ 04 A I, Patent No. WO2013064153, Priority date 31 Oct 2011, Priority No. DK20110070591Research output: Patent
- Published
Interaction of Amino Acid and Dipeptide beta-Naphthylamide Derivatives with Hyaluronic Acid and Human Serum Albumin Studied by Capillary Electrophoresis Frontal Analysis
Ye, F., Xie, Y., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, Jan 2013, In: Chromatographia. 76, 1-2, p. 49-57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of supercritical fluid chromatography for testing of PEG adducts in pharmaceuticals
Schou-Pedersen, A. M. V., Østergaard, Jesper, Johansson, M., Dubant, S., Frederiksen, R. B. & Hansen, S. H., 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 256-261Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kvalitetssikring af målrettede nanopartikler til kemoterapi
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Lægemiddelforskning. 2012, p. 50-51Research output: Contribution to journal › Journal article › Communication
- Published
Medicindepot dannes efter injektion i leddet
Larsen, Susan Weng, Thing, M. A., Østergaard, Jesper, Kristensen, Jesper Langgaard, Hansen, M. & Larsen, C. S., 2013, In: Lægemiddelforskning. 2013, p. 38-40Research output: Contribution to journal › Journal article › Research
- Published
Metallomics in drug development: characterization of a liposomal cisplatin drug formulation in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Analytical and Bioanalytical Chemistry. 405, 6, p. 1845-1854Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation
Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physicochemical profiling of drug candidates using capillary-based techniques
Jensen, H., Larsen, Susan Weng, Larsen, C. S. & Østergaard, Jesper, 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging
Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration
Larsen, Susan Weng, Østergaard, Jesper, Yaghmur, Anan, Jensen, H. & Larsen, C., 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Physico-chemical characterization of liposomes and drug substance-liposome interactions in pharmaceutics using capillary electrophoresis and electrokinetic chromatography
Franzen, U. & Østergaard, Jesper, Dec 2012, In: Journal of Chromatography A. 1267, p. 32-44 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning
Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Affinity capillary electrophoresis method for investigation of bile salts complexation with sulfobutyl ether-ß-cyclodextrin
Østergaard, Jesper, Jensen, H. & Holm, R., 2012, In: Journal of Separation Science. 35, 20, p. 2764-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behaviour of HPMC compacts investigated using UV-imaging
Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition
Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In: Langmuir. 28, 5, p. 2881-2889Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem
Nilsson, C., Edwards, K., Eriksson, J., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C. S., Urtti, A. & Yaghmur, Anan, 2012, In: Langmuir. 28, 32, p. 11755-11766Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug release into hydrogel-based subcutaneous surrogates studied by UV imaging
Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 71, p. 27-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties
Jensen, M., Canning, A., Chiha, S., Bouquerel, P., Pedersen, J. T., Østergaard, Jesper, Cuvillier, O., Sasaki, I., Hureau, C. & Faller, P., 2012, In: Chemistry: A European Journal. 18, 16, p. 4836-4839 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis
Ye, F., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 61, p. 176-183Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells
Yang, L., Fawcett, J. P., Østergaard, Jesper, Zhang, H. & Tucker, I. G., 2012, In: Molecular Pharmaceutics. 9, 1, p. 29-36Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
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