Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
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In situ formed suspensions for local sustained action of celecoxib following intra-articular administration
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Jacobsen, Stine, Thomsen, M. H., Lindegaard, Casper, Andersen, P. H. & Larsen, C. S., 2009. 2 p.Research output: Contribution to conference › Poster › Research
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In vitro and in vivo characteristics of celecoxib in situ formed suspensions for intra-articular administration
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Thomsen, M. H., Jacobsen, Stine, Skonberg, C., Hansen, S. H., Jensen, Henrik Elvang & Larsen, C. S., 2011, In: Journal of Pharmaceutical Sciences. 100, 10, p. 4330-4337 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning
Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357Research output: Contribution to journal › Journal article › Research › peer-review
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A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
Thing, M., Agårdh, L., Larsen, Susan Weng, Rasmussen, R., Pallesen, J., Mertz, N., Kristensen, Jesper Langgaard, Hansen, M., Østergaard, Jesper & Larsen, C. S., 2014, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4021–4029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis
Zhuang, G., Poulsen, N. N., Petersen, Nickolaj J., Østergaard, Jesper & Jensen, H., 2 Sep 2013, 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. p. 1054-1057 4 p. 6559903Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication
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A method for studies on interactions between a gold-based drug and plasma proteins based on capillary electrophoresis with inductively coupled plasma mass spectrometry detection
Nguyen, T. T. T. N., Østergaard, Jesper & Gammelgaard, Bente, 2 Sep 2015, In: Analytical and Bioanalytical Chemistry. 407, 28, p. 8497-8503 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
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Affinity capillary electrophoresis for identification and investigation of human Gc-globulin (vitamin D-binding protein) and its isoforms interacting with G-actin
Pedersen, J. T., Østergaard, Jesper, Houen, G. & Heegaard, N. H. H., 2008, In: Electrophoresis. 29, 8, p. 1723-1733Research output: Contribution to journal › Journal article › Research › peer-review
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Affinity capillary electrophoresis method for investigation of bile salts complexation with sulfobutyl ether-ß-cyclodextrin
Østergaard, Jesper, Jensen, H. & Holm, R., 2012, In: Journal of Separation Science. 35, 20, p. 2764-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: International Journal of Pharmaceutics. 609, 12 p., 121183.Research output: Contribution to journal › Journal article › Research › peer-review
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An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution
Etherson, K., Dunn, C., Matthews, W., Pamelund, H., Barragat, C., Sanderson, N., Izumi, T., Mathews, C. D. C., Halbert, G., Wilson, C., McAllister, M., Mann, J., Østergaard, Jesper, Butler, J. & Khadra, I., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 150, p. 24-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An investigation of drug compact topography as relates to intrinsic dissolution rates determined by dissolution imaging
Brown, B., Fazili, Z., Ward, A., Walton, K., Blunt, L., Østergaard, Jesper & Asare-Addo, K., 2021, In: Journal of Drug Delivery Science and Technology. 61, 10 p., 102143.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of proteins in solution using affinity capillary electrophoresis
Heegaard, N. H. H., Schou, C. & Østergaard, Jesper, 2008, Affinity chromatography: methods and protocols. Zachariou, M. (ed.). 2 ed. USA: Humana Press, p. 303-338Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Analysis of selenium nanoparticles in human plasma by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry
Gronbaek-Thorsen, F., Hansen, R. H., Østergaard, Jesper, Gammelgaard, Bente & Moller, L. H., 2021, In: Analytical and Bioanalytical Chemistry. 413, 8, p. 2247-2255Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV Imaging in Formulation Development
Sun, Y. & Østergaard, Jesper, 2017, In: Pharmaceutical Research. 34, 5, p. 929–940 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV dissolution imaging to pharmaceutical systems
Brown, B., Ward, A., Fazili, Z., Østergaard, Jesper & Asare-Addo, K., 2021, In: Advanced Drug Delivery Reviews. 177, 26 p., 113949.Research output: Contribution to journal › Review › Research › peer-review
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Application of retention factors in affinity electrokinetic chromatography and capíllary electrophoresis
Østergaard, Jesper, 2007, In: Analytical Sciences. 23, 4, p. 489-492Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing
Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Development and Industrial Pharmacy. 34, 3, p. 297-304Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.Research output: Contribution to journal › Journal article › Research › peer-review
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Automated coating procedures to produce poly(ethylene glycol) brushes in fused-silica capillaries
Poulsen, N. N., Østergaard, Jesper, Petersen, Nickolaj J., Daasbjerg, K., Iruthayaraj, J., Dedinaite, A., Makuska, R. & Jensen, H., Feb 2017, In: Journal of Separation Science. 40, 3, p. 779–788Research output: Contribution to journal › Journal article › Research › peer-review
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Behaviour of HPMC compacts investigated using UV-imaging
Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of low-molecular-weight cationic ligands to chondroitin sulfate as studied by capillary electrophoresis frontal analysis
Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. R. & Larsen, C. S., 2009, In: Open Analytical Chemistry Journal. 3, p. 16-21Research output: Contribution to journal › Journal article › Research › peer-review
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Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis
Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, Jesper & Fotaki, N., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioreversible derivatives of phenol 1: the role of human serum albumin as related to the stability and binding properties of carbonate esters with fatty acid-like structures in aqueous solution and biological media
Østergaard, Jesper & Larsen, C. S., 2007, In: Molecules. 12, 10, p. 2380-2395Research output: Contribution to journal › Journal article › Research › peer-review
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Bioreversible derivatives of phenol. 2. Reactivity of carbonoate esters with fatty acid-like structures towards hydrolysis in aqueous solutions
Østergaard, Jesper & Larsen, C. S., 2007, In: Molecules. 12, 10, p. 2396-2412Research output: Contribution to journal › Journal article › Research › peer-review
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CE frontal analysis based on simultaneous UV and contactless conductivity detection: a general setup for studying noncovalent interactions
Jensen, H., Østergaard, Jesper, Thomsen, A. E. & Hansen, S. H., 2007, In: Electrophoresis. 28, 3, p. 322-327Research output: Contribution to journal › Journal article › Research › peer-review
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CE frontal analysis employing contactless conductivity detection for determination of CMCs of non-UV absorbing charged surfactants
Jensen, H., Østergaard, Jesper & Hansen, S. H., 2007, In: Electrophoresis. 28, 17, p. 2975-2980Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a liposome-based formulation of oxaliplatin using capillary electrophoresis: encapsulation and leakage
Franzen, U., Nguyen, T. T. N. T., Vermehren, C., Gammelgaard, Bente & Østergaard, Jesper, 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 1, p. 16-22Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition
Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In: Langmuir. 28, 5, p. 2881-2889Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem
Nilsson, C., Edwards, K., Eriksson, J., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C. S., Urtti, A. & Yaghmur, Anan, 2012, In: Langmuir. 28, 32, p. 11755-11766Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the complexation of tauro- and glyco-conjugated bile salts with ¿-cyclodextrin and 2-hydroxypropyl-¿-cyclodextrin using affinity capillary electrophoresis
Holm, R., Hartvig, R. A., Nicolajsen, H. V., Westh, P. & Østergaard, Jesper, 2008, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 61, 1-2, p. 161 - 169Research output: Contribution to journal › Journal article › Research › peer-review
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Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies
Azmi, I. D. M., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of external calibration and isotope dilution LC-ICP-MS/MS for quantitation of oxytocin and its selenium analogue in human plasma
Grønbæk-Thorsen, F., Jensen, C., Østergaard, Jesper, Møller, L. H. & Gammelgaard, Bente, 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 6479–6488Research output: Contribution to journal › Journal article › Research › peer-review
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Complexation of tauro- and glyco-conjugated bile salts with three neutral ß-CDs studied by ACE
Holm, R., Nicolajsen, H. V., Hartvig, R. A., Westh, P. & Østergaard, Jesper, 2007, In: Electrophoresis. 28, 20, p. 3745-3752Research output: Contribution to journal › Journal article › Research › peer-review
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Complexation of tauro- and glycoconjugated bile salts with a-cyclodextrin and hydroxypropyl-a-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling
Holm, R., Schönbeck, C., Askjær, S., Jensen, H., Westh, P. & Østergaard, Jesper, 2011, In: Journal of Separation Science. 34, 22, p. 3221-3230Research output: Contribution to journal › Journal article › Research › peer-review
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Concomitant monitoring of implant formation and drug release of in situ forming poly (lactide-co-glycolide acid) implants in a hydrogel matrix mimicking the subcutis using UV–vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 150, p. 95-106Research output: Contribution to journal › Journal article › Research › peer-review
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Controlled release - macromolecular prodrugs
Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2007, Prodrugs: challenges and rewards. Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H. & Tilley, J. W. (eds.). New York: Springer, p. 379-416Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Cu(II) mediates kineticallyl distinct, non-amyloidogenic aggregation of amyloid-β peptides
Pedersen, J. T., Østergaard, Jesper, Rozlosnik, N., Gammelgaard, Bente & Heegaard, N. H. H., 2011, In: Journal of Biological Chemistry. 286, 30, p. 26952-26963Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis
Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of platinum drug release and liposome stability in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 5 Jun 2013, In: International Journal of Pharmaceutics. 449, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of stability constants of tauro- and glyco-conjugated bile salts with the negatively charged sulfobutylether-β-cyclodextrin: comparison of affinity capillary electrophoresis and isothermal titration calorimetry and thermodynamic analysis of the interaction
Holm, R., Østergaard, Jesper, Schönbeck, C., Jensen, H., Shi, W., Peters, G. H. & Westh, P., Apr 2014, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 78, 1-4, p. 185-194Research output: Contribution to journal › Journal article › Research › peer-review
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Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice
Murillo-Arbizu, M., González-Peñas, E., Hansen, S. H., Amézqueta, S. & Østergaard, Jesper, 2008, In: Food and Chemical Toxicology. 46, 6, p. 2251-2257Research output: Contribution to journal › Journal article › Research › peer-review
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Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization
Bock, Frederik, Hu, A., Cicale, V., Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866Research output: Contribution to journal › Journal article › Research › peer-review
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Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation
Storgaard, Ida Klitzing, Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 2020, In: Journal of Pharmaceutical Sciences. 109, 4, p. P1529-1536Research output: Contribution to journal › Journal article › Research › peer-review
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Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model
Larsen, Susan Weng, Østergaard, Jesper, Poulsen, S., Schulz, B. & Larsen, C. S., 2007, In: European Journal of Pharmaceutical Sciences. 31, 3-4, p. 172-179Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods
Sarnes, A., Østergaard, Jesper, Jensen, S. S., Aaltonen, J., Rantanen, Jukka, Hirvonen, J. & Peltonen, L., 20 Nov 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 511-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
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255
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Research output: Contribution to journal › Journal article › Research › peer-review
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