Jesper Østergaard

Jesper Østergaard

Professor

ORCID: 0000-0003-3448-4237

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  1. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging

    Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, H., Aug 2011, In: Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Monitoring of antimicrobial drug chloramphenicol release from electrospun nano-and microfiber mats using UV imaging and bacterial bioreporters

    Preem, L., Bock, Frederik, Hinnu, M., Putrinš, M., Sagor, K., Tenson, T., Meos, A., Østergaard, Jesper & Kogermann, K., 2019, In: Pharmaceutics. 11, 9, 19 p., 487.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel

    Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Nye depotlægemidler til injektion i gigtramte led: kan laboratoriemodeller reducere antallet af dyreforsøg

    Frost, A. B., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Lægemiddelforskning. p. 46-48

    Research output: Contribution to journal › Journal article › Communication

  5. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse

    Frost, A. B., Larsen, F., Østergaard, Jesper, Larsen, Susan Weng, Lindegaard, Casper, Hansen, H. R. & Larsen, C. S., 2010, In: European Journal of Pharmaceutical Sciences. 41, p. 10-15

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation

    Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure

    Nilsson, C., Østergaard, Jesper, Larsen, Susan Weng, Larsen, C., Urtti, A. & Yaghmur, Anan, 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    PRODRUGS OF NAPROXEN AND DICLOFENAC

    Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 17 Mar 2016, IPC No. A61K 45/ 06 A I, Patent No. US2016074523, Priority date 28 Apr 2014, Priority No. WO2014EP58530

    Research output: Patent

  10. Published

    PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)

    Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 10 May 2013, IPC No. C07D 487/ 04 A I, Patent No. WO2013064153, Priority date 31 Oct 2011, Priority No. DK20110070591

    Research output: Patent

  11. Published

    Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies

    Jensen, S. S., Jensen, H., Goodall, D. M. & Østergaard, Jesper, 30 Nov 2016, In: Journal of Pharmaceutical and Biomedical Analysis. 131, p. 113-123 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging

    Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 25 Oct 2017, In: Journal of Pharmaceutical and Biomedical Analysis. 145, p. 682-691 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Physico-chemical characterization of liposomes and drug substance-liposome interactions in pharmaceutics using capillary electrophoresis and electrokinetic chromatography

    Franzen, U. & Østergaard, Jesper, Dec 2012, In: Journal of Chromatography A. 1267, p. 32-44 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics: parenteral depots for intra-articular administration

    Pedersen, B. T., Østergaard, Jesper, Larsen, Susan Weng, Cornett, Claus, Ankersen, M. & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 1, p. 62-71

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Physicochemical characterization of a PEGylated liposomal drug formulation using capillary electrophoresis

    Franzen, U., Vermehren, C., Jensen, H. & Østergaard, Jesper, 2011, In: Electrophoresis. 32, 6-7, p. 738-748

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Physicochemical profiling of drug candidates using capillary-based techniques

    Jensen, H., Larsen, Susan Weng, Larsen, C. S. & Østergaard, Jesper, 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat

    Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach

    Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis

    Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection

    Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Rapid exchange of metal between Zn7-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes

    Pedersen, J. T., Hureau, C., Hemmingsen, Lars Bo Stegeager, Heegaard, N. H. H., Østergaard, Jesper, Vasák, M. & Faller, P., 2012, In: Biochemistry. 51, 8, p. 1697-1706

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides

    Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  25. Published

    Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate

    Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels

    Ye, F., Yaghmur, Anan, Jensen, H., Larsen, Susan Weng, Larsen, C. & Østergaard, Jesper, 17 Jul 2011, In: European Journal of Pharmaceutical Sciences. 43, 4, p. 236-243

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Real-time UV imaging of nicotin release from transdermal patch

    Østergaard, Jesper, Meng-Lund, E., Larsen, Susan Weng, Larsen, C. S., Petersson, K., Lenke, J. & Jensen, H., 2010, In: Pharmaceutical Research. 27, p. 2614-2623

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix

    Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

    Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging

    Gaunø, M. H., Vilhelmsen, T., Larsen, C. C., Bøtker, Johan Peter, Wittendorff, J., Rantanen, Jukka & Østergaard, Jesper, Sep 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 83, p. 49-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery

    Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C., Larsen, Susan Weng, Yaghmur, Anan, Østergaard, Jesper & Jensen, H., Dec 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C. S., Larsen, Susan Weng, Jensen, H., Yaghmur, Anan & Østergaard, Jesper, 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journal › Review › Research

  34. Published

    SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

    Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications

    Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, Anan, 7 Aug 2013, In: Biomaterials. 34, 33, p. 8491-8503

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid

    Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin

    Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Simulated synovial fluids for in vitro drug and prodrug release testing of depot injectables intended for joint injection

    Thing, M., Mertz, Nina, Ågårdh, L., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C., 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 169-176 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing

    Østergaard, Jesper, Wu, J., Naelapää, K., Bøtker, Johan Peter, Jensen, H. & Rantanen, Jukka, Apr 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1149-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Simultaneous evaluation of ligand binding properies and protein size by electrophoresis and taylor dispersion in capillaries

    Østergaard, Jesper & Jensen, H., 2009, In: Analytical Chemistry. 81, 20, p. 8644-8648

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Simultaneous measurement of phosphorus and platinum by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry (SEC-ICPMS) using xenon as reactive collision gas for charaterization of platinum drug liposomes

    Nguyen, T. T. N. T., Stürup, Stefan, Østergaard, Jesper, Franzen, U. & Gammelgaard, Bente, 2011, In: Journal of Analytical Atomic Spectrometry. 26, 7, p. 1466-1473

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species

    Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media

    Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Stability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensions

    Møller, E. H., Holst, Birgitte, Nielsen, L. H., Pedersen, P. S. & Østergaard, Jesper, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 13-18

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy

    Schou-Pedersen, A. M. V., Cornett, Claus, Nyberg, N., Østergaard, Jesper & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions

    Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse

    Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution

    Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Towards in vitro in vivo correlation for modified release subcutaneously administered insulins

    Bock, Frederik, Lin, E., Larsen, C., Jensen, H., Huus, K., Larsen, Susan Weng & Østergaard, Jesper, 2020, In: European Journal of Pharmaceutical Sciences. 145, 10 p., 105239.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables

    Mertz, Nina, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 20 Jul 2019, In: International Journal of Pharmaceutics. 566, p. 445-453

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    UV imaging for in vitro dissolution and release studies: Initial experiences

    Østergaard, Jesper, Lenke, J., Jensen, S. S., Sun, Y. & Ye, F., 2014, In: Dissolution Technologies. 21, 4, p. 27-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    UV imaging in pharmaceutical analysis

    Østergaard, Jesper, 5 Jan 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 147, p. 140-148

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    UV-imaging visulaliserer frigivelse af lægemiddelstoffer

    Ye, F., Meng-Lund, E., Yaghmur, Anan, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2010, In: Lægemiddelforskning. 2010, p. 46-48

    Research output: Contribution to journal › Journal article › Communication

  55. Published

    UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup

    Sun, Y., Chapman, A., Larsen, Susan Weng, Jensen, H., Petersen, Nickolaj J., Goodall, D. M. & Østergaard, Jesper, 5 Jun 2018, In: Analytical Chemistry. 90, 11, p. 6413-6418

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Use of correction factors in mobility shift affinity capillary electrophoresis for weak analyte - ligand interactions

    Østergaard, Jesper, Jensen, H. & Holm, R., 2009, In: Journal of Separation Science. 32, 10, p. 1712-1721

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration

    Larsen, Susan Weng, Østergaard, Jesper, Yaghmur, Anan, Jensen, H. & Larsen, C., 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination

    Ward, A., Walton, K., Box, K., Østergaard, Jesper, Gillie, L. J., Conway, B. R. & Asare-Addo, K., 15 Sep 2017, In: International Journal of Pharmaceutics. 530, 1-2, p. 139-144 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    pH-triggered drug release from biodegradable microwells for oral drug delivery

    Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.

    Research output: Contribution to journal › Journal article › Research › peer-review

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