Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery

    Cun, D., Foged, Camilla, Yang, Mingshi, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 70-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Polymeric nanocarriers for siRNA delivery: challenges and future prospects

    Cun, D., Jensen, L. B., Nielsen, Hanne Mørck, Moghimi, S. M. & Foged, Camilla, 2008, In: Journal of Biomedical Nanotechnology. 4, 3, p. 258-275

    Research output: Contribution to journal › Review › Research

  3. Polymeric nanocarriers for siRNA delivery: challenges and future prospects

    Cun, D., Jensen, L. B., Nielsen, Hanne Mørck, Moghimi, S. M. & Foged, C., 2008, In: Journal of Biomedical Nanotechnology. 4, 3, p. 258-275

    Research output: Contribution to journal › Review › Research

  4. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, Camilla & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, C. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.

    Research output: Contribution to journal › Conference abstract in journal › Research

  7. Studies towards improved stability and permeability of a cell-penetrating peptide

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, H. & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  8. Published

    Studies towards improved stability and permeability of a cell-penetrating peptide

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  9. Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, P. P., Skindersø, M. E., Hansen, P. R., Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, L., Aug 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  10. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, Peter Panduro, Skindersø, M. E., Hansen, Paul Robert, Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, Luca, Aug 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  11. Published

    Stereochemistry and Intermolecular Interactions Influence Carrier Peptide-Mediated Insulin Delivery

    Diedrichsen, Ragna Guldsmed, Tuelung, P. S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Molecular Pharmaceutics. 20, 2, p. 1202–1212

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Carrier peptide interactions with liposome membranes induce reversible clustering by surface adsorption and shape deformation

    Diedrichsen, Ragna Guldsmed, Vetri, V., Prévost, S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Journal of Colloid and Interface Science. 650, Part B, p. 1821-1832

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

    Diedrichsen, Ragna Guldsmed, Rønholt, Stine, Werner, U., Besenius, M., Leberer, E., Kristensen, Mie & Nielsen, Hanne Mørck, 2021, In: Journal of Controlled Release. 338, p. 8-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate

    Eirheim, H. U., Bundgaard, C. & Nielsen, Hanne Mørck, 2004, In: Toxicology in Vitro. 18, 5, p. 649-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

    Eissa, N. G., Sayers, E. J., Birch, D., Patel, S. G., Tsai, Y. H., Nielsen, Hanne Mørck & Jones, A. T., 8 Jan 2020, In: Biochemical Journal. 477, 1, p. 45-60 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  17. Published

    Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: A comparative study with epithelial cell cultures

    Foerg, C., Weller, K. M., Rechsteiner, H., Nielsen, Hanne Mørck, Fernandez-Carneado, J., Brunisholz, R., Giralt, E. & Merkle, H. P., 2008, In: The AAPS Journal. 10, 2, p. 349-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: A comparative study with epithelial cell cultures

    Foerg, C., Weller, K. M., Rechsteiner, H., Nielsen, Hanne Mørck, Fernandez-Carneado, J., Brunisholz, R., Giralt, E. & Merkle, H. P., 2008, In: The AAPS Journal. 10, 2, p. 349-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen

    Foged, C., Ingvarsson, P. T., Follmann, F., Christensen, D. & Nielsen, Hanne Mørck, 2013, In: Lægemiddelforskning. 2013, p. 41-43

    Research output: Contribution to journal › Journal article › Research

  20. Published

    Genetisk nanomedicin til behandling af leddegigt

    Foged, Camilla, Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  21. Published

    Cell-penetrating peptides for cytosolic delivery of biomacromolecules

    Foged, Camilla, Jing, X. & Nielsen, Hanne Mørck, 2010, Organelle-specific pharmaceutical nanotechnology. Weissig, V. & D'Souza, G. G. M. (eds.). Hoboken: Wiley, p. 403-432

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  22. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)

    Foged, C., Nielsen, Hanne Mørck & Frøkjær, S., 2007, In: Journal of Liposome Research. 17, 3-4

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

    Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA

    Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931

    Research output: Patent

  25. Published

    Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen

    Foged, Camilla, Ingvarsson, P. T., Follmann, F., Christensen, D. & Nielsen, Hanne Mørck, 2013, In: Lægemiddelforskning. 2013, p. 41-43

    Research output: Contribution to journal › Journal article › Research

  26. Published

    Cell-penetrating peptides for drug delivery across membrane barriers

    Foged, Camilla & Nielsen, Hanne Mørck, 2008, In: Expert Opinion on Drug Delivery. 5, 1, p. 105-17 12 p.

    Research output: Contribution to journal › Review › Research

  27. Published

    Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Journal of Liposome Research. 17, 3-4

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Genetisk nanomedicin til behandling af leddegigt

    Foged, C., Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  30. Cell-penetrating peptides for cytosolic delivery of biomacromolecules

    Foged, C., Jing, X. & Nielsen, Hanne Mørck, 2010, Organelle-specific pharmaceutical nanotechnology. Weissig, V. & D'Souza, G. G. M. (eds.). Hoboken: Wiley, p. 403-432

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  31. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles

    García-Díaz, M., Birch, D., Wan, F. & Nielsen, Hanne Mørck, Jan 2018, In: Advanced Drug Delivery Reviews. 124, p. 107-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Antimicrobial activity of GN peptides and their mode of action

    Godballe, T., Mojsoska, B., Nielsen, Hanne Mørck & Jenssen, H., 13 Dec 2015, In: Biopolymers. 106, 2, p. 172–183 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Nielsen, Hanne Mørck & Hansen, Paul Robert, 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  35. Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa

    Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, Hanne Mørck & Hansen, P. R., 7 Jul 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  36. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

    Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, Hanne Mørck, Damborg, Peter Panduro & Hansen, Paul Robert, 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Nielsen, Hanne Mørck & Hansen, Paul Robert, 7 Jul 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  38. AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, Hanne Mørck & Hansen, P. R., 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  39. Published

    Assessment of mucoadhesion using small deformation rheology revisited

    Rønholt, Stine, Vissing, K. J. & Nielsen, Hanne Mørck, Apr 2017, In: Nordic Rheology Society Annual Transactions. 25, p. 63 7 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  40. Published

    Animal models for evaluation of oral delivery of biopharmaceuticals

    Rønholt, Stine, Nielsen, L. H. & Nielsen, Hanne Mørck, Dec 2017, In: Journal of Controlled Release. 268, p. 57-71 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  41. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

    Rønholt, Stine, Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, Hanne Mørck, 1 Jan 2019, In: Drug Delivery. 26, 1, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction

    Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Shuffled lipidation pattern and degree of lipidation determines the membrane interaction behavior of a linear cationic membrane-active peptide

    Hedegaard, S. F., Bruhn, D. S., Khandelia, H., Cardenas, M. & Nielsen, Hanne Mørck, 2020, In: Journal of Colloid and Interface Science. 578, p. 584-597 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Drug delivery studies in Caco-2 monolayers. II. Absorption enhancer effects of lysophosphatidylcholines

    Hovgaard, L., Brøndsted, H. & Nielsen, Hanne Mørck, 14 Feb 1995, In: International Journal of Pharmaceutics. 114, 2, p. 141-149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

    Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Synthesis of carbon quantum dot-poly lactic-co-glycolic acid hybrid nanoparticles for chemo-photothermal therapy against bacterial biofilms

    Huang, Z., Zhou, T., Yuan, Y., Klodziska, S. N., Zheng, T., Sternberg, C., Nielsen, Hanne Mørck, Sun, Y. & Wan, F., 2020, In: Journal of Colloid and Interface Science. 577, p. 66-74 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Nanoparticle-mediated pulmonary drug delivery: state of the art towards efficient treatment of recalcitrant respiratory tract bacterial infections

    Huang, Z., Klodzinska, S. N., Wan, F. & Nielsen, Hanne Mørck, 2021, In: Drug Delivery and Translational Research. 11, p. 1634–1654

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin

    Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Designing CAF-adjuvanted dry powder vaccines: spray drying preserves the adjuvant activity of CAF01

    Ingvarsson, P. T., Schmidt, S. T., Christensen, D., Larsen, N. B., Hinrichs, W. L. J., Andersen, P., Rantanen, Jukka, Nielsen, Hanne Mørck, Yang, Mingshi & Foged, Camilla, 8 Feb 2013, In: Journal of Controlled Release. 167, 3, p. 256-264

    Research output: Contribution to journal › Journal article › Research › peer-review

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