Birger Brodin Larsen

Birger Brodin Larsen

Professor


Publication year:
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51 - 75 out of 111Page size: 25
  1. 2014
  2. Published

    PAT1 (SLC36A1) shows nuclear localization and affect growth of smooth muscle cells from rats

    Jensen, A., Figueiredo-Larsen, E. M., Holm, R., Broberg, M. L., Larsen, Birger Brodin & Nielsen, C. U., Jan 2014, In: A J P: Endocrinology and Metabolism (Online). 306, p. E65-E74

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Generation of primary cultures of bovine brain endothelial cells and setup of cocultures with rat astrocytes

    Helms, H. C. & Larsen, Birger Brodin, 2014, In: Methods in molecular biology (Clifton, N.J.). 1135, p. 365-82 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2013
  5. Published

    Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro

    Nielsen, C. U., Frølund, S. B., Abdulhadi, S., Sari, H., Langthaler, L., Nøhr, M. K., Kall, M. A., Larsen, Birger Brodin & Holm, R., Nov 2013, In: British Journal of Pharmacology. 170, 5, p. 1041-52 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Serotonin transporter protein (SERT) and P-glycoprotein (P-gp) binding activity of montanine and coccinine from three species of Haemanthus L. (Amaryllidaceae)

    Stafford, G. I., Birer, C., Larsen, Birger Brodin, Christensen, Søren Brøgger, Eriksson, A. H., Jäger, A. & Rønsted, Nina, Sep 2013, In: South African Journal of Botany. 88, p. 101-106 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent

    Berthelsen, R., Nielsen, C. U. & Larsen, Birger Brodin, Jul 2013, In: Journal of Pharmacy and Pharmacology. 65, 7, p. 970-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Current status of rational design of prodrugs targeting the intestinal di/tri-peptide transporter hPEPT1 (SLC15A1)

    Saaby, Lasse, Nielsen, C. U., Steffansen, B., Larsen, Birger Brodin & Larsen, S. B. L., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 307–314

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Potential involvement of the proton-coupled amino acid transporter PAT1 (SLC36A1) in the delivery of pharmaceutical agents

    Frølund, S. B., Nøhr, M. K., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 293-306

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2012
  11. Published

    Identification and Characterization of a Novel Nontranslated Sequence Variant of the Human Intestinal Di-/Tripeptide Transporter, hPEPT1

    Søndergaard, H. B., Nielsen, C. U. & Larsen, Birger Brodin, 31 Dec 2012, In: International Journal of Peptides. 2012, 2012, 7 p., 743472.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Carrier-mediated ¿-aminobutyric acid transport across the basolateral membrane of human intestinal Caco-2 cell monolayers

    Nielsen, C. U., Carstensen, M. & Larsen, Birger Brodin, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 458-462

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Function and expression of the proton-coupled amino acid transporter Slc36a1 along the rat gastrointestinal tract: Implications for intestinal absorption of gaboxadol

    Broberg, M. L., Holm, R. K., Tønsberg, H., Frølund, S. B., Ewon, K. B., Nielsen, A. L., Larsen, Birger Brodin, Jensen, A., Kall, M. A., Nielsen, C. U. & Christensen, K. V., 2012, In: British Journal of Pharmacology. 167, 3, p. 654-665

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    In vitro evidence for the brain glutamate efflux hypothesis: brain endothelial cells cocultured with astrocytes display a polarized brain-to-blood transport of glutamate

    Helms, H. C., Madelung, R., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, 2012, In: Glia. 60, 6, p. 882-893

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids

    Eriksson, A. H., Rønsted, Nina, Jäger, A. K., Sendra, J. R. & Larsen, Birger Brodin, 2012, In: Journal of Pharmacy and Pharmacology. 64, 11, p. 1667-1677 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2011
  17. Published

    Affinity and translocation relationships via hPEPT1 of H-Xaa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs

    Omkvist, D. H., Trangbæk, D. J., Mildon, J., Paine, J. S., Larsen, Birger Brodin, Begtrup, M. & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 2, p. 327-331

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Calu-3 cells grown under AIC and LCC conditions: implications for dipeptide uptake and transepithelial transport of substances

    Stentebjerg-Andersen, A., Notlevesen, I. V., Larsen, Birger Brodin & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 19-26

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2010
  20. Published

    Paracellular tightness and claudin-5 expression is increased in the BCEC/Astrocyte blood-brain barrier model by increasing media buffer capacity during growth

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Larsen, Birger Brodin, Dec 2010, In: The AAPS Journal. 12, 4, p. 759-770

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    5-Hydroxy-L-tryptohan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

    Broberg, M. L., Holm, R., Jensen, K. G., Sveigaard, C., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: European Journal of Pharmaceutical Sciences. 39, 1-3, p. 68-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A quantitative structure-activity relationship for translocation of tripeptides via the human proton-coupled peptide transporter, hPEPT1 (SLC15A1)

    Omkvist, D. H., Larsen, S. B., Nielsen, C. U., Steffansen, B., Olsen, L., Jørgensen, Flemming Steen & Larsen, Birger Brodin, 2010, In: The AAPS Journal. 12, 3, p. 385-396

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen

    Omkvist, D. H., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: British Journal of Pharmacology. 161, 8, p. 1793-1805

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics

    Frølund, S., Holm, R., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: British Journal of Pharmacology. 161, 3, p. 589-600

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    d-Aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1)

    Frølund, S., Marquez, O. C., Larsen, M., Larsen, Birger Brodin & Nielsen, C. U., 2010, In: British Journal of Pharmacology. 159, 6, p. 1339-1353

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2009
  27. Published

    In Vitro cutaneous application of ISCOMs on human skin enhances delivery of hydrophobic model compounds through the stratum corneum

    Madsen, H. B., Ifversen, P., Madsen, F., Larsen, Birger Brodin, Hausser, I. & Nielsen, Hanne Mørck, 2009, In: The AAPS Journal. 11, 4, p. 728-739

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Discovery of ligands for the human intestinal di-/tripeptide transporter (hPEPT1) using af QSAR-assisted virtual screening strategy

    Larsen, S. B., Omkvist, D. H., Larsen, Birger Brodin, Nielsen, C. U., Steffansen, B., Olsen, L. & Jørgensen, Flemming Steen, 2009, In: ChemMedChem. 4, 9, p. 1439-1445

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan

    Larsen, M., Larsen, R., Jensen, K. G., Larsen, Birger Brodin & Nielsen, C. U., 2009, In: British Journal of Pharmacology. 157, p. 1380-1389

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2008
  31. Published

    Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1

    Søndergaard, H. B., Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2008, In: European Journal of Pharmaceutical Sciences. 33, 4-5, p. 332-342

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

    Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396

    Research output: Contribution to journal › Journal article › Research › peer-review

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