Basolateral glycylsarcosine (Gly-Sar) transport in Caco-2 cell monolayers is pH dependent

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Transepithelial di/tripeptide transport in enterocytes occurs via the apical proton-coupled peptide transporter, hPEPT1 (SLC15A1) and a basolateral peptide transporter, which has only been characterized functionally. In this study we examined the pH dependency, substrate uptake kinetics and substrate specificity of the transporter.
Original languageEnglish
JournalJournal of Pharmacy and Pharmacology
Issue number7
Pages (from-to)970-9
Number of pages10
Publication statusPublished - Jul 2013

ID: 46203180