Birger Brodin Larsen
Professor
CNS Drug Delivery and Barrier Modelling
Universitetsparken 2
2100 København Ø
- 2008
- Published
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories
Hayeshi, R., Hilgendorf, C., Arthursson, P., Augustijns, P., Larsen, Birger Brodin, Dehertogh, P., Fisher, K., Fossati, L., Hovenkamp, E., Korjamo, T., Masungi, C., Maubon, N., Mols, R., Mullertz, Anette , Mönkkönen, J., O´Driscoll, C., Oppers-Tiemissen, H. M., Ragnarsson, E. G. E., Rooseboom, M. & Ungell, A., 2008, In: European Journal of Pharmaceutical Sciences. 35, 5, p. 383-396Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sorption and mobility of ivermectin in different soils
Krogh, K. A., Søborg, T., Larsen, Birger Brodin & Halling-Sørensen, B., 2008, In: Journal of Environmental Quality. 37, 6, p. 2202-2211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: Characterization of conditions for affinity and transport experiments in Caco-2 cells.
Larsen, M., Larsen, Birger Brodin, Frølund, Bente & Nielsen, C. U., 2008, In: European Journal of Pharmaceutical Sciences. 35, 1-2, p. 86-95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3
Søndergaard, H. B., Larsen, Birger Brodin & Nielsen, C. U., 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 3, p. 611-622Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Basolateral peptide transport in intestinal cells is pH dependent
Juul Nielsen, M., Nielsen, C. U. & Larsen, Birger Brodin, 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Molekylær biofarmaci - når medicinen skyder genvej!
Gram, L. K., Omkvist, D. H., Larsen, M., Nielsen, C. U., Larsen, Birger Brodin & Steffansen, I. D., 2007, In: Lægemiddelforskning. p. 16-17Research output: Contribution to journal › Journal article › Communication
- Published
Optimization of a cell-based flourescent probe assay for measuring substrate translocation via the proton-coupled intestinal di/tri-peptide transporter hPEPT1
Omkvist, D. H., Nielsen, C. U., Steffansen, B. & Larsen, Birger Brodin, 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Peptide Transporters in Drug Delivery
Larsen, Birger Brodin, Steffansen, B. & Nielsen, C. U., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Proton-coupled basolateral dipeptide transport in a human intestinal cell line, Caco-2
Larsen, Birger Brodin, Nielsen, M. J. & Nielsen, C. U., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
The human proton-coupled amino acid transporter (hPAT1) is a transport system for GABA-like drugs
Broberg, M. L., Frølund, Bente, Larsen, Birger Brodin & Nielsen, C. U., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2006
- Published
Genetic variants of the human dipeptide transporter PEPT1
Anderle, P., Nielsen, C. U., Pinsonneault, J., Krog, P. L., Larsen, Birger Brodin & Sadée, W., 1 Feb 2006, In: Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 636-646 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carbonic anhydrase imhibitors. Transepithelial transport of novel anticancer sulfonamide inhibitors of the cancer-associated isozyme CA IX is dependent on the p.gp efflux transporter
Vullo, D., Steffansen, B., Larsen, Birger Brodin, Supuran, C. T., Scozzafava, A. & Nielsen, C. U., 2006, In: Bioorganic & Medicinal Chemistry Letters. 14, 7, p. 2418-2427Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carrier-mediated dipeptide transport in a human lung epithelial cell line, Calu-3
Nielsen, C. U., Søndergaard, H. B. & Larsen, Birger Brodin, 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
In vitro evaluation of N-methyl amide tripeptidomimetics as substrates for the human intestinal di-/tri-peptide transporter hPEPT1
Andersen, R., Nielsen, C. U., Begtrup, M., Jørgensen, Flemming Steen, Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2006, In: European Journal of Pharmaceutical Sciences. 28, 4, p. 325-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin increases peptide transport capacity in the proximal tubule kidney cell line SKPT0193-Cl.2.
Rquez, B., Nielsen, C. U. & Larsen, Birger Brodin, 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Oral Gly-Sar absorption is inhibited bu a high-affinity PEPT1 inhibitor Lys-Z-NO2-Pro
Eriksson, A. H., Rist, G. M., Larsen, Birger Brodin & Steffansen, B., 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Proton dependent transport of amino acids in Caco-2 cells
Broberg, M. L., Larsen, Birger Brodin & Nielsen, C. U., 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2005
- Published
Characterization of rPEPT2-mediated Gly-Sar transport parameters in the rat kidney proximal tubule cell line SKPT-0193 cl.2 cultured in basic growth media
Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2005, In: Molecular Pharmaceutics. 2, 2, p. 98-108 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model
Foged, Camilla, Larsen, Birger Brodin, Frøkjær, Sven & Sundblad, A., 2005, In: Internation Journal of Pharmaceutics. 298, 2, p. 315-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pyrimidine and nucleoside gamma-esters of L-Glu-Sar: synthesis, stability and interaction with hPEPT1
Eriksson, A. H., Elm, P. L., Begtrup, M., Larsen, Birger Brodin, Nielsen, R. & Steffansen, B., 2005, In: European Journal of Pharmaceutical Sciences. 25, 1, p. 145-154 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances in therapeutic applications of human transporters
Nielsen, C. U., Våbenø, J., Andersen, R., Larsen, Birger Brodin & Steffansen, B., 2005, In: Expert Opinion on Therapeutic Patents. 15, 2, p. 153-166 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The F28Y substitution in the human intestinal di/tri-peptide transporter hPEPT1, causes altered pH-dependency of Gly-Sar transport
Nielsen, C. U., Krog, P., Anderlee, P., Sadeé, W. & Larsen, Birger Brodin, 2005.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
hPEPT1 Affinity and Translocation of Selected Gln-Sar and Glu-Sar Dipeptide Derivatives
Eriksson, A. H., Elm, P. L., Begtrup, M., Nielsen, R., Steffansen, B. & Larsen, Birger Brodin, 2005, In: Molecular Pharmaceutics. 2, 3, p. 242-249Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
In-depth evaluation of Gly-Sar transport parameters as a function of culture time in the Caco-2 cell model
Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 1 Jan 2004, In: European Journal of Pharmaceutical Sciences. 21, 1, p. 77-86 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2
Bravo, S. A., Nielsen, C. U., Amstrup, J., Frøkjær, Sven & Larsen, Birger Brodin, 2004, In: American Journal of Physiology - Renal Physiology. 286, 2, p. 385-393Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299175
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Design of prodrugs targeting the intestinal di/tri‐peptide transporter hPEPT1 (SLC15A1
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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A bovine in vitro blood-brain barrier model under oxygenglucose deprivation (OGD) condition
Research output: Contribution to conference › Poster › Research
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