Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
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Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging
Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, H., Aug 2011, In: Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410Research output: Contribution to journal › Journal article › Research › peer-review
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Monitoring of antimicrobial drug chloramphenicol release from electrospun nano-and microfiber mats using UV imaging and bacterial bioreporters
Preem, L., Bock, Frederik, Hinnu, M., Putrinš, M., Sagor, K., Tenson, T., Meos, A., Østergaard, Jesper & Kogermann, K., 2019, In: Pharmaceutics. 11, 9, 19 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
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Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel
Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.Research output: Contribution to journal › Journal article › Research › peer-review
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Nye depotlægemidler til injektion i gigtramte led: kan laboratoriemodeller reducere antallet af dyreforsøg
Frost, A. B., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Lægemiddelforskning. p. 46-48Research output: Contribution to journal › Journal article › Communication
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On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44Research output: Contribution to journal › Journal article › Research › peer-review
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On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse
Frost, A. B., Larsen, F., Østergaard, Jesper, Larsen, Susan Weng, Lindegaard, Casper, Hansen, H. R. & Larsen, C. S., 2010, In: European Journal of Pharmaceutical Sciences. 41, p. 10-15Research output: Contribution to journal › Journal article › Research › peer-review
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Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation
Larsen, A. T., Ohlsson, A. G., Polentarutti, B., Barker, R. A., Phillips, A. R., Abu-Rmaileh, R., Dickinson, P. A., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , 2013, In: European Journal of Pharmaceutical Sciences. 48, 1-2, p. 339-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure
Nilsson, C., Østergaard, Jesper, Larsen, Susan Weng, Larsen, C., Urtti, A. & Yaghmur, Anan, 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PRODRUGS OF NAPROXEN AND DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 17 Mar 2016, IPC No. A61K 45/ 06 A I, Patent No. US2016074523, Priority date 28 Apr 2014, Priority No. WO2014EP58530Research output: Patent
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PRODRUGS OF NON- STEROID ANTI - INFLAMMATORY AGENTS (NSAIDS)
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 10 May 2013, IPC No. C07D 487/ 04 A I, Patent No. WO2013064153, Priority date 31 Oct 2011, Priority No. DK20110070591Research output: Patent
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Jensen, S. S., Jensen, H., Goodall, D. M. & Østergaard, Jesper, 30 Nov 2016, In: Journal of Pharmaceutical and Biomedical Analysis. 131, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 25 Oct 2017, In: Journal of Pharmaceutical and Biomedical Analysis. 145, p. 682-691 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physico-chemical characterization of liposomes and drug substance-liposome interactions in pharmaceutics using capillary electrophoresis and electrokinetic chromatography
Franzen, U. & Østergaard, Jesper, Dec 2012, In: Journal of Chromatography A. 1267, p. 32-44 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics: parenteral depots for intra-articular administration
Pedersen, B. T., Østergaard, Jesper, Larsen, Susan Weng, Cornett, Claus, Ankersen, M. & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 1, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
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Physicochemical characterization of a PEGylated liposomal drug formulation using capillary electrophoresis
Franzen, U., Vermehren, C., Jensen, H. & Østergaard, Jesper, 2011, In: Electrophoresis. 32, 6-7, p. 738-748Research output: Contribution to journal › Journal article › Research › peer-review
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Physicochemical profiling of drug candidates using capillary-based techniques
Jensen, H., Larsen, Susan Weng, Larsen, C. S. & Østergaard, Jesper, 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
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Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat
Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach
Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid exchange of metal between Zn7-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes
Pedersen, J. T., Hureau, C., Hemmingsen, Lars Bo Stegeager, Heegaard, N. H. H., Østergaard, Jesper, Vasák, M. & Faller, P., 2012, In: Biochemistry. 51, 8, p. 1697-1706Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides
Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels
Ye, F., Yaghmur, Anan, Jensen, H., Larsen, Susan Weng, Larsen, C. & Østergaard, Jesper, 17 Jul 2011, In: European Journal of Pharmaceutical Sciences. 43, 4, p. 236-243Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time UV imaging of nicotin release from transdermal patch
Østergaard, Jesper, Meng-Lund, E., Larsen, Susan Weng, Larsen, C. S., Petersson, K., Lenke, J. & Jensen, H., 2010, In: Pharmaceutical Research. 27, p. 2614-2623Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix
Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging
Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging
Gaunø, M. H., Vilhelmsen, T., Larsen, C. C., Bøtker, Johan Peter, Wittendorff, J., Rantanen, Jukka & Østergaard, Jesper, Sep 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 83, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery
Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of in vitro release models in formulation development and quality control of parenteral depots
Larsen, C., Larsen, Susan Weng, Yaghmur, Anan, Østergaard, Jesper & Jensen, H., Dec 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295Research output: Contribution to journal › Journal article › Research › peer-review
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Role of in vitro release models in formulation development and quality control of parenteral depots
Larsen, C. S., Larsen, Susan Weng, Jensen, H., Yaghmur, Anan & Østergaard, Jesper, 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295Research output: Contribution to journal › Review › Research
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SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization
Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665Research output: Contribution to journal › Journal article › Research › peer-review
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SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications
Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, Anan, 7 Aug 2013, In: Biomaterials. 34, 33, p. 8491-8503Research output: Contribution to journal › Journal article › Research › peer-review
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Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid
Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin
Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simulated synovial fluids for in vitro drug and prodrug release testing of depot injectables intended for joint injection
Thing, M., Mertz, Nina, Ågårdh, L., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C., 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 169-176 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing
Østergaard, Jesper, Wu, J., Naelapää, K., Bøtker, Johan Peter, Jensen, H. & Rantanen, Jukka, Apr 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1149-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous evaluation of ligand binding properies and protein size by electrophoresis and taylor dispersion in capillaries
Østergaard, Jesper & Jensen, H., 2009, In: Analytical Chemistry. 81, 20, p. 8644-8648Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous measurement of phosphorus and platinum by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry (SEC-ICPMS) using xenon as reactive collision gas for charaterization of platinum drug liposomes
Nguyen, T. T. N. T., Stürup, Stefan, Østergaard, Jesper, Franzen, U. & Gammelgaard, Bente, 2011, In: Journal of Analytical Atomic Spectrometry. 26, 7, p. 1466-1473Research output: Contribution to journal › Journal article › Research › peer-review
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Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species
Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media
Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425Research output: Contribution to journal › Journal article › Research › peer-review
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Stability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensions
Møller, E. H., Holst, Birgitte, Nielsen, L. H., Pedersen, P. S. & Østergaard, Jesper, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 13-18Research output: Contribution to journal › Journal article › Research › peer-review
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Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy
Schou-Pedersen, A. M. V., Cornett, Claus, Nyberg, N., Østergaard, Jesper & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › Research › peer-review
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Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions
Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse
Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution
Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.Research output: Contribution to journal › Journal article › Research › peer-review
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Towards in vitro in vivo correlation for modified release subcutaneously administered insulins
Bock, Frederik, Lin, E., Larsen, C., Jensen, H., Huus, K., Larsen, Susan Weng & Østergaard, Jesper, 2020, In: European Journal of Pharmaceutical Sciences. 145, 10 p., 105239.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Research output: Contribution to journal › Journal article › Research › peer-review
Published