Lene Jørgensen

Lene Jørgensen

Associate Professor

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    51 - 86 out of 86Page size: 50
    1. 2011
    2. Published

      Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

      Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?

      Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil-water interface-Interacial shear measurements

      Baldursdóttir, S. G. & Jørgensen, Lene, 2011, In: Colloids and Surfaces B: Biointerfaces. 87, p. 96-102

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2010
    6. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journal › Journal article › Research

    7. Published

      Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces

      Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In: European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Interfacial complexes between a protein and lipophilic ions at an oil - water interface

      Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Issues in Development of Biodrug Delivery Systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    10. Published

      Issues in development of biodrug delivery systems

      Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    11. Published

      Multivariate analysis of protein physical stability

      Guzman, P., Jørgensen, Lene, Strachan, C., Rades, T. & Medlicott, N., 2010.

      Research output: Contribution to conference › Conference abstract for conference › Research

    12. Published

      Penetration of gel and liquid state liposomes into barrier-impaired skin

      Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793

      Research output: Contribution to journal › Conference article › Research › peer-review

    13. Published

      Proteiner i lægemidler - de sætter sig alle de forkerte steder

      Baldursdóttir, S. G., Nielsen, S. H., Fullerton, M. & Jørgensen, Lene, 2010, In: Lægemiddelforskning. 2010, p. 43-45

      Research output: Contribution to journal › Journal article › Research

    14. Published

       Adsorption of proteins at the oil/water inerface - observation of protein adsorption by interfacial shear stress measurements

      Baldursdóttir, S. G., Fullerton, M. S., Nielsen, S. H. & Jørgensen, Lene, 2010, In: Colloids and Surfaces B: Biointerfaces. 79, p. 41-46

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2009
    16. Published

      Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems

      Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    17. Published

      Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems

      Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Biotechnology-based pharmaceuticals

      Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    19. Published

      Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines

      Jørgensen, Lene & Nielsen, Hanne Mørck, 2009, Wiley. 413 p.

      Research output: Book/Report › Book › Research › peer-review

    20. Published

      Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis

      Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Infrared spectroscopy of protein pharmaceuticals

      van de Weert, Marco & Jørgensen, Lene, 2009, Advances in Biomedical Spectroscopy: Biological and Biomedical Infrared Spectrocopy. Barth, A. & Haris, P. I. (eds.). Amsterdam: IOS Press, Vol. 2. p. 168-177

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    22. Published

      Lipid based drug delivery systems for proteins: Physical stability of proteins at the oil-water interface

      Jørgensen, Lene, 2009, VDM Verlag Dr. Müller Aktiengesellschaft & C o. KG.

      Research output: Book/Report › Book › Research › peer-review

    23. Published

      Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence  (TIRF)

      Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients

      Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230

      Research output: Contribution to journal › Review › Research

    25. 2008
    26. Published

      Alternative routes of administration for systemic delivery of protein pharmaceuticals

      Møller, E. H. & Jørgensen, Lene, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 89-94

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis

      Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar

      Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29

      Research output: Contribution to journal › Journal article › Research

    29. Published

      Metode til screening af modificerede proteinlægemidler under opbevaring

      Petersen, C., Jørgensen, Lene, Hostrup, S., Bukrinsky, J. T. & Frøkjær, Sven, 2008, In: Lægemiddelforskning. p. 16-18

      Research output: Contribution to journal › Journal article › Communication

    30. Published

      Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

      Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2007
    32. Published

      Liposomer i lægemiddelforskning

      Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15

      Research output: Contribution to journal › Journal article › Communication

    33. Published

      Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles

      Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. 2006
    35. Published

      Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S., Frøkjær, Sven & Rischel, C., 1 Jan 2006, In: Pharmaceutical Research. 23, 1, p. 148-155 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Interfacial adsorption of insulin - conformational changes and reversibility of adsorption

      Mollmann, S. H., Jørgensen, Lene, Bukrinsky, J. T., Elofsson, U., Norde, W. & Frøkjær, Sven, 2006, In: European Journal of Pharmaceutical Sciences. 27, 2-3, p. 194-204

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Kinetics of insulin adsorption and gelation at the oil-water interface monitored using fluorescence correlation spectroscopy

      Donsmark, J., Jørgensen, Lene, Mollmann, S. H., Frøkjær, Sven & Rischel, C., 2006, In: Pharmaceutical Research. 23, 1, p. 148-155

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. 2005
    39. Published

      Factors of importance for a successful delivery system for proteins

      van de Weert, Marco, Jørgensen, Lene, Horn Moeller, E. & Frøkjær, Sven, Nov 2005, In: Expert Opinion on Drug Delivery. 2, 6, p. 1029-37 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    40. 2004
    41. Published

      Probing structural changes of proteins incorporated into water-in-oil emulsions

      Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      In vitro release of insulin aspart incorporated into water-in-oil emulsions

      Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Drug Delivery Science and Technology. 14, 6, p. 455-459

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Micropipette manipulation a technique to evaluate the stability of water-in-oil emulsions containing proteins

      Jørgensen, Lene, Kim, D. H., Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Pharmaceutical Sciences. 93, 12, p. 2994-3003

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. 2003
    45. Published

      Secondary structure alteration in insulin and growth hormone water-in-oil emulsions

      Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2003, In: Internation Journal of Pharmaceutics. 254, 1, p. 7-10

      Research output: Contribution to journal › Journal article › Research › peer-review

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