Lasse Saaby

Lasse Saaby

Affiliated Associate Professor, Guest Researcher

Member of:

    ORCID: 0000-0003-4271-8304

    Publication year:
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    1. Published

      Short communication: Influence of pasteurization on the active compounds in medicinal plants to be used in dairy products

      Jäger, A. K., Saaby, Lasse, Kudsk, D. S., Witt, K. C. & Mølgaard, Per, 2010, In: Journal of Dairy Science. 93, 6, p. 2351-2353

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A Critical View on In Vitro Analysis of P-glycoprotein (P-gp) Transport Kinetics

      Saaby, Lasse & Larsen, Birger Brodin, Sep 2017, In: Journal of Pharmaceutical Sciences. 106, 9, p. 2257-2264 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

      Ronco, T., Aragao, F. M., Saaby, Lasse, Christensen, Jørn Bolstad, Permin, A., Williams, Andrew Richard, Thamsborg, Stig Milan & Olsen, Rikke Heidemann, 2021, In: PLoS ONE. 16, 10, 13 p., e0258207.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

      Jørgensen, N. S., Saaby, Lasse, Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Antibiotics. 9, 6, 11 p., 327.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity

      Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

      Langthaler, Kristine, Jones, C. R., Saaby, Lasse, Bundgaard, C. & Larsen, Birger Brodin, 2024, In: Fluids and Barriers of the CNS. 21, 1, 15 p., 11.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

      Mortensen, Janni Støvring, Saaby, Lasse, Rønholt, Stine & Nielsen, Hanne Mørck, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 174, p. 106-110

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis

      Larsen, A. T., Åkesson, P., Juréus, A., Saaby, Lasse, Abu-Rmaileh, R., Abrahamsson, B., Østergaard, Jesper & Mullertz, Anette , Dec 2013, In: Pharmaceutical Research. 30, 12, p. 3101-13 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)

      Saaby, Lasse, Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In: Planta Medica. 76, 12, p. 1171

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    10. Published

      Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

      Christophersen, P. C., Fano, M., Saaby, Lasse, Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2015, In: Current Pharmaceutical Design. 21, 19, p. 2611-28 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates

      Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: European Journal of Pharmaceutical Sciences. 112, p. 112-121 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Considerations regarding use of solvents in in vitro cell based assays

      Timm, M., Saaby, Lasse, Moesby, L. & Hansen, E. W., Oct 2013, In: Cytotechnology. 65, 5, p. 887-894 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Current status of rational design of prodrugs targeting the intestinal di/tri-peptide transporter hPEPT1 (SLC15A1)

      Saaby, Lasse, Nielsen, C. U., Steffansen, B., Larsen, Birger Brodin & Larsen, S. B. L., 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 307–314

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Dark chocolate as a stable carrier of microencapsulated Akkermansia muciniphila and Lactobacillus casei

      Marcial-Coba, M. S., Saaby, Lasse, Knoechel, Susanne & Nielsen, Dennis Sandris, 2019, In: FEMS Microbiology Letters. 366, 2, p. 1-6 fny290.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates

      Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: Data in Brief. 16, p. 655-659 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB)

      Helms, H. C. C., Kristensen, Mie, Saaby, Lasse, Fricker, G. & Larsen, Birger Brodin, 2020, Handbook of Experimental Pharmacology. Springer, Vol. 273. p. 151-183

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    18. Published

      Efficacy of a novel antimicrobial hydrogel for eradication of Staphylococcus epidermidis, Staphylococcus aureus and Cutibacterium acnes from preformed biofilm and treatment performance in an in vivo MRSA wound model

      Ronco, T., Aragao, M. F., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Bionda, N., Lantz, E. E. & Olsen, Rikke Heidemann, 2021, In: JAC-Antimicrobial Resistance. 3, 3, 7 p., dlab108.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Evaluation of immunomodulating and anti-inflammatory effects of a herbal remedy based on rose hip powder (Rosa canina L.)

      Saaby, Lasse, 2011, København: Det Farmaceutiske Fakultet. 130 p.

      Research output: Book/Report › Ph.D. thesis › Research

    20. Published

      Flavonoids and the CNS

      Jäger, A. K. & Saaby, Lasse, 10 Feb 2011, In: Molecules. 16, 2, p. 1471-1485

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

      Nielsen, A. K. R., Lilieholm-Røngren, L., Schmid, B., Holst, B., Larsen, Birger Brodin & Saaby, Lasse, 2024, In: Stem Cell Research. 76, 5 p., 103348.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease

      Pultz, I. S., Hill, M., Vitanza, J. M., Wolf, C., Saaby, Lasse, Liu, T., Winkle, P. & Leffler, D. A., Jul 2021, In: Gastroenterology. 161, 1, p. 81-93.e3

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

      Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, Nana Isabella, Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility

      López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, Lasse, Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., Jun 2018, In: Food Hydrocolloids. 79, p. 117-126 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      IPEC-J2 MDR1, a Novel High-Resistance Cell Line with Functional Expression of Human P-glycoprotein (ABCB1) for Drug Screening Studies

      Saaby, Lasse, Helms, H. C. C. & Larsen, Birger Brodin, 1 Feb 2016, In: Molecular Pharmaceutics. 13, 2, p. 640-52 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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