Lasse Saaby

Lasse Saaby

Researcher


  1. 2022
  2. Published

    Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

    Mortensen, Janni Støvring, Saaby, Lasse, Harloff-Helleberg, Stine & Nielsen, Hanne Mørck, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 174, p. 106-110

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration

    Ronco, T., Kappel, L. H., Aragao, M. F., Biagi, N., Svenningsen, S., Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Holmstrøm, K., Klitgaard, J. K., Sabat, A. J., Akkerboom, V., Monaco, M., Tinelli, M., Friedrich, A. W., Jana, B. & Olsen, Rikke Heidemann, 2022, In: Frontiers in Microbiology. 12, 786173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2021
  5. Published

    Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

    Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

    Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2020
  8. Published

    The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

    Ambjørner, Sophie Emilie Blomgren, Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, Nils & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

    Jørgensen, N. S., Saaby, Lasse, Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, S. W., Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In: Antibiotics. 9, 6, 11 p., 327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2019
  11. Published

    SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

    Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dark chocolate as a stable carrier of microencapsulated Akkermansia muciniphila and Lactobacillus casei

    Marcial-Coba, M. S., Saaby, Lasse, Knøchel, Susanne & Nielsen, Dennis Sandris, 2019, In: FEMS Microbiology Letters. 366, 2, p. 1-6 fny290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2018
  14. Published

    Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates

    Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: European Journal of Pharmaceutical Sciences. 112, p. 112-121 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates

    Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: Data in Brief. 16, p. 655-659 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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