Lasse Saaby

Lasse Saaby

Affiliated Associate Professor, Guest Researcher

Member of:

    ORCID: 0000-0003-4271-8304

    Publication year:
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    31 - 40 out of 42Page size: 10
    1. 2021
    2. Published

      A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity

      Ronco, T., Aragao, F. M., Saaby, Lasse, Christensen, Jørn Bolstad, Permin, A., Williams, Andrew Richard, Thamsborg, Stig Milan & Olsen, Rikke Heidemann, 2021, In: PLoS ONE. 16, 10, 13 p., e0258207.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Efficacy of a novel antimicrobial hydrogel for eradication of Staphylococcus epidermidis, Staphylococcus aureus and Cutibacterium acnes from preformed biofilm and treatment performance in an in vivo MRSA wound model

      Ronco, T., Aragao, M. F., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Bionda, N., Lantz, E. E. & Olsen, Rikke Heidemann, 2021, In: JAC-Antimicrobial Resistance. 3, 3, 7 p., dlab108.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

      Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, Nana Isabella, Ozgür, Burak, Holst, B., Shusta, E., Hall, Vanessa Jane, Saaby, Lasse, Hyttel, P. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutical Sciences. 156, 14 p., 105577.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

      Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Gluten Degradation, Pharmacokinetics, Safety, and Tolerability of TAK-062, an Engineered Enzyme to Treat Celiac Disease

      Pultz, I. S., Hill, M., Vitanza, J. M., Wolf, C., Saaby, Lasse, Liu, T., Winkle, P. & Leffler, D. A., Jul 2021, In: Gastroenterology. 161, 1, p. 81-93.e3

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2022
    8. Published

      Barrier properties of ex vivo porcine intestinal mucus are highly independent of isolation and storage conditions

      Mortensen, Janni Støvring, Saaby, Lasse, Rønholt, Stine & Nielsen, Hanne Mørck, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 174, p. 106-110

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Insight Into the Anti-staphylococcal Activity of JBC 1847 at Sub-Inhibitory Concentration

      Ronco, T., Kappel, L. H., Aragao, M. F., Biagi, N., Svenningsen, Søren Wedel, Christensen, Jørn Bolstad, Permin, A., Saaby, Lasse, Holmstrøm, K., Klitgaard, J. K., Sabat, A. J., Akkerboom, V., Monaco, M., Tinelli, M., Friedrich, A. W., Jana, B. & Olsen, Rikke Heidemann, 2022, In: Frontiers in Microbiology. 12, 786173.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Physical and barrier changes in gastrointestinal mucus induced by the permeation enhancer sodium 8-[(2-hydroxybenzoyl)amino]octanoate (SNAC)

      Mortensen, Janni Støvring, Bohr, S. S. R., Rønholt, Stine, Hatzakis, Nikos, Saaby, Lasse & Nielsen, Hanne Mørck, 2022, In: Journal of Controlled Release. 352, p. 163-178 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 2024
    12. Published

      Application of a new MDCKII-MDR1 cell model to measure the extent of drug distribution in vitro at equilibrium for prediction of in vivo unbound brain-to-plasma drug distribution

      Langthaler, Kristine, Jones, C. R., Saaby, Lasse, Bundgaard, C. & Larsen, Birger Brodin, 2024, In: Fluids and Barriers of the CNS. 21, 1, 15 p., 11.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

      Nielsen, A. K. R., Lilieholm-Røngren, L., Schmid, B., Holst, B., Larsen, Birger Brodin & Saaby, Lasse, 2024, In: Stem Cell Research. 76, 5 p., 103348.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 4863000