Jette Jacobsen

Jette Jacobsen

Associate Professor

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    1. Published

      Aqueous gel composition and its use

      Bar-Shalom, Daniel, Jacobsen, Jette, Dalby, K., Pedersen, Anne Marie Lynge & Vilmann, Peter, Oct 2015, Priority date 21 May 2015, Priority No. EP20140169457 20140522

      Research output: Patent

    2. Published

      Development of a μDissolution-Permeation model with in situ drug concentration monitoring

      Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example

      Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Dissolution Model Development: Formulation Effects and Filter Complications

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.

      Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

      Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans

      Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

      Christiansen, M. L., Holm, R., Kristensen, J., Kreilgaard, M., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 164-172

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

      Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

      Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Analytical aspects of printed oral dosage forms

      Edinger, M., Jacobsen, Jette, Bar-Shalom, Daniel, Rantanen, Jukka & Genina, Natalja, 20 Dec 2018, In: International Journal of Pharmaceutics. 553, 1-2, p. 97-108

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing

      Eleftheriadis, G. K., Monou, P. K., Bouropoulos, N., Bøtker, Johan Peter, Rantanen, Jukka, Jacobsen, Jette, Vizirianakis, I. S. & Fatouros, D. G., 2020, In: Journal of Pharmaceutical Sciences. 109, 9, p. 2757-2766

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21

      Research output: Contribution to journal › Journal article › Communication

    14. Published

      An Evaluation of the Physicochemical Properties of Preservative-Free 0.005% (w/v) Latanoprost Ophthalmic Solutions, and the Impact on In Vitro Human Conjunctival Goblet Cell Survival

      Freiberg, Josefine, Nagstrup, Anne Hedengran, Heegaard, Steffen, Petrovski, G., Jacobsen, Jette, Cvenkel, B. & Kolko, Miriam, 2022, In: Journal of Clinical Medicine. 11, 11, 3137.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Identification of globular protein structures in human whole and parotid saliva

      Hamulic, Benjamin, Jacobsen, Jette, Bar-Shalom, Daniel & Pedersen, Anne Marie Lynge, 2022. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    16. Published

      Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

      Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa

      Hansen, S. E., Marxen, E., Janfelt, Christian & Jacobsen, Jette, Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 250-257

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Multi-material 3D printing of programmable and stretchable oromucosal patches for delivery of saquinavir

      He, S., Radeke, C., Jacobsen, Jette, Lind, J. U. & Mu, Huiling, 2021, In: International Journal of Pharmaceutics. 610, 9 p., 121236.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      In vitro and ex vivo evaluation of bilayered effervescent microenvironmental pH modifying buccal films with saquinavir

      He, S., Nielsen, C. U., Mu, Huiling & Jacobsen, Jette, 2022, In: Journal of Drug Delivery Science and Technology. 78, 7 p., 103954.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro

      He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films

      He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties

      Nagstrup, Anne Hedengran, Freiberg, Josefine, Hansen, Pernille May, Jacobsen, Jette, Larsen, Susan Weng, Rønholt, Stine, Freude, Kristine, Boix‐lemonche, G., Petrovski, G., Heegaard, Steffen & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs

      Holm, R., Jørgensen, E. B., Harborg, M., Larsen, R. S., Holm, P., Mullertz, Anette & Jacobsen, Jette, 2011, In: European Journal of Pharmaceutical Sciences. 42, p. 416-422

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH in TR146 cell culture, porcine buccal mucosa and Göttingen minipigs

      Holm, R., Meng-Lund, E., Andersen, M. B., Jespersen, M. L., Karlsson, J., Garmer, M., Jørgensen, E. B. & Jacobsen, Jette, 13 May 2013, In: European Journal of Pharmaceutical Sciences. 49, 2, p. 117-124

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

      Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

      Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Medicated chewing gum

      Jacobsen, Jette, Christrup, Lona Louring & Jensen, N., 2004, In: American Journal of Drug Delivery. 2, p. 75-88 14 p.

      Research output: Contribution to journal › Journal article › Research

    28. Published

      Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

      Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture

      Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

      Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Polymer coated liposomes for use in the oral cavity - A study of the in vitro toxicity, effect on cell permeability and interaction with mucin

      Klemetsrud, T., Kjøniksen, A., Hiorth, M., Jacobsen, Jette & Smistad, G., 2018, In: Journal of Liposome Research. 28, 1, p. 62–73 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

      Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Accepted/In press

      Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus

      Klitgaard, Mette, Jacobsen, Jette, Kristensen, M. N., Berthelsen, R. & Mullertz, Anette , 2024, (Accepted/In press) In: Drug Delivery and Translational Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33

      Research output: Contribution to journal › Journal article › Research

    35. Published

      Predicting in vivo performance of fenofibrate amorphous solid dispersions using in vitro non-sink dissolution and dissolution permeation setup

      Lentz, K. A., Plum, J., Steffansen, B., Arvidsson, P. O., Omkvist, D. H., Pedersen, A. J., Sennbro, C. J., Pedersen, G. P. & Jacobsen, Jette, 2021, In: International Journal of Pharmaceutics. 610, 8 p., 121174.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

      Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Development of an ex vivo retention model simulating bioadhesion in the oral cavity using human saliva and physiologically relevant irrigation media

      Madsen, K. D., Sander, C., Baldursdottir, S., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 20 May 2013, In: International Journal of Pharmaceutics. 448, 2, p. 373-81 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

      Maher, S., Leonard, T. W., Jacobsen, Jette & Brayden, D. J., 2009, In: Advanced Drug Delivery Reviews. p. 1427-1449

      Research output: Contribution to journal › Review › Research

    42. Published

      Are mucin dispersions a barrier to small molecules in oromucosal drug delivery?

      Marxen, E., Mosgaard, M. D., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2017.

      Research output: Contribution to conference › Poster › Research › peer-review

    43. Published

      Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

      Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In: Pharmaceutical Research. 35, 3, 12 p., 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Effect of cryoprotectants for maintaining drug permeability barriers in porcine buccal mucosa

      Marxen, E., Axelsen, M. C., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2016, In: International Journal of Pharmaceutics. 511, 1, p. 599-605 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

      Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Can freeze protectants preserve the integrity of permeability barriers in porcine buccal mucosa?

      Marxen, E., Axelsen, M., Pedersen, Anne Marie Lynge & Jacobsen, Jette, Jul 2015.

      Research output: Contribution to conference › Poster › Research › peer-review

    47. Published

      Mucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules

      Marxen, E., Mosgaard, M. D., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 121, p. 121-128

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Polymeric Lids for Microcontainers for Oral Protein Delivery

      Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Conscious and anaesthetised Göttingen mini-pigs as an in-vivo model for buccal absorption - pH-dependent absorption of metoprolol from bioadhesive tablets

      Meng-Lund, E., Jacobsen, Jette, Andersen, M. B., Jespersen, M. L., Karlsson, J., Garmer, M., Jørgensen, E. B. & Holm, R., May 2014, In: Drug Development and Industrial Pharmacy. 40, 5, p. 604-610 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      A mechanistic based approach for enhancing buccal mucoadhesion of chitosan

      Meng-Lund, E., Muff-Westergaard, C., Sander, C., Madelung, P. & Jacobsen, Jette, 30 Jan 2014, In: International Journal of Pharmaceutics. 461, 1-2, p. 280-5 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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