Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
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Affinity capillary electrophoresis for identification and investigation of human Gc-globulin (vitamin D-binding protein) and its isoforms interacting with G-actin
Pedersen, J. T., Østergaard, Jesper, Houen, G. & Heegaard, N. H. H., 2008, In: Electrophoresis. 29, 8, p. 1723-1733Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides
Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2019, Clinical Applications of Capillary Electrophoresis. Springer, Vol. 1972. p. 109-123 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species
Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach
Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979Research output: Contribution to journal › Journal article › Research › peer-review
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In-Solution IgG Titer Determination in Fermentation Broth Using Affibodies and Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 28 Apr 2020, In: ACS Omega. 5, 18, p. 10519-10524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Behaviour of HPMC compacts investigated using UV-imaging
Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353Research output: Contribution to journal › Journal article › Research › peer-review
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Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward a New Approach for Diagnosis and Patient Stratification
Poulsen, N. N., Pedersen, M. E., Østergaard, Jesper, Petersen, Nickolaj J., Nielsen, C. T., Heegaard, N. H. H. & Jensen, H., 2016, In: Analytical Chemistry. 88, 18, p. 9056-61 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Flow induced dispersion analysis rapidly quantifies proteins in human plasma samples
Poulsen, N. N., Andersen, N. Z., Østergaard, Jesper, Zhuang, G., Petersen, Nickolaj J. & Jensen, H., 7 Jul 2015, In: The Analyst. 140, 13, p. 4365-69 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Automated coating procedures to produce poly(ethylene glycol) brushes in fused-silica capillaries
Poulsen, N. N., Østergaard, Jesper, Petersen, Nickolaj J., Daasbjerg, K., Iruthayaraj, J., Dedinaite, A., Makuska, R. & Jensen, H., Feb 2017, In: Journal of Separation Science. 40, 3, p. 779–788Research output: Contribution to journal › Journal article › Research › peer-review
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Monitoring of antimicrobial drug chloramphenicol release from electrospun nano-and microfiber mats using UV imaging and bacterial bioreporters
Preem, L., Bock, Frederik, Hinnu, M., Putrinš, M., Sagor, K., Tenson, T., Meos, A., Østergaard, Jesper & Kogermann, K., 2019, In: Pharmaceutics. 11, 9, 19 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods
Sarnes, A., Østergaard, Jesper, Jensen, S. S., Aaltonen, J., Rantanen, Jukka, Hirvonen, J. & Peltonen, L., 20 Nov 2013, In: European Journal of Pharmaceutical Sciences. 50, 3-4, p. 511-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetics of the esterification of active pharmaceutical ingredients containing carboxylic Acid functionality in polyethylene glycol: formulation implications
Schou-Pedersen, A. M. V., Hansen, S. H., Moesgaard, B. & Østergaard, Jesper, Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2424-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of microwave oven heating for prediction of drug-excipient compatibilities and accelerated stability studies
Schou-Pedersen, A. M. V., Østergaard, Jesper, Cornett, Claus & Hansen, S. H., 15 May 2015, In: International Journal of Pharmaceutics. 485, 1-2, p. 97-107 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure elucidation and quantification of impurities formed between 6-aminocaproic acid and the excipients citric acid and sorbitol in an oral solution using high-resolution mass spectrometry and nuclear magnetic resonance spectroscopy
Schou-Pedersen, A. M. V., Cornett, Claus, Nyberg, N., Østergaard, Jesper & Hansen, S. H., 25 Mar 2015, In: Journal of Pharmaceutical and Biomedical Analysis. 107C, p. 333-340 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of supercritical fluid chromatography for testing of PEG adducts in pharmaceuticals
Schou-Pedersen, A. M. V., Østergaard, Jesper, Johansson, M., Dubant, S., Frederiksen, R. B. & Hansen, S. H., 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 88, p. 256-261Research output: Contribution to journal › Journal article › Research › peer-review
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Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel
Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.Research output: Contribution to journal › Journal article › Research › peer-review
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Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation
Storgaard, Ida Klitzing, Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 2020, In: Journal of Pharmaceutical Sciences. 109, 4, p. P1529-1536Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV Imaging in Formulation Development
Sun, Y. & Østergaard, Jesper, 2017, In: Pharmaceutical Research. 34, 5, p. 929–940 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 25 Oct 2017, In: Journal of Pharmaceutical and Biomedical Analysis. 145, p. 682-691 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Concomitant monitoring of implant formation and drug release of in situ forming poly (lactide-co-glycolide acid) implants in a hydrogel matrix mimicking the subcutis using UV–vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 150, p. 95-106Research output: Contribution to journal › Journal article › Research › peer-review
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UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup
Sun, Y., Chapman, A., Larsen, Susan Weng, Jensen, H., Petersen, Nickolaj J., Goodall, D. M. & Østergaard, Jesper, 5 Jun 2018, In: Analytical Chemistry. 90, 11, p. 6413-6418Research output: Contribution to journal › Journal article › Research › peer-review
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A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
Thing, M., Agårdh, L., Larsen, Susan Weng, Rasmussen, R., Pallesen, J., Mertz, N., Kristensen, Jesper Langgaard, Hansen, M., Østergaard, Jesper & Larsen, C. S., 2014, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4021–4029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simulated synovial fluids for in vitro drug and prodrug release testing of depot injectables intended for joint injection
Thing, M., Mertz, Nina, Ågårdh, L., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C., 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 169-176 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modification of concomitant drug release from oil vehicles using drug-prodrug combinations to achieve sustained balanced analgesia after joint installation
Thing, M., Jensen, S. S., Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2012, In: International Journal of Pharmaceutics. 439, 1-2, p. 246-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat
Thing, M., Lu, Y., Agårdh, L., Larsen, C. S., Østergaard, Jesper, He, W., Wu, W., Larsen, F. & Larsen, Susan Weng, 15 Jul 2013, In: International Journal of Pharmaceutics. 451, 1-2, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro release from oil injectabels for intra-articular administration: importance of interfacial area, diffusivity and partitioning
Thing, M. A., Larsen, C. S., Østergaard, Jesper, Jensen, H. & Larsen, Susan Weng, 2012, In: European Journal of Pharmaceutical Sciences. 45, 3, p. 351-357Research output: Contribution to journal › Journal article › Research › peer-review
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Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › Research › peer-review
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Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
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Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination
Ward, A., Walton, K., Box, K., Østergaard, Jesper, Gillie, L. J., Conway, B. R. & Asare-Addo, K., 15 Sep 2017, In: International Journal of Pharmaceutics. 530, 1-2, p. 139-144 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition
Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In: Langmuir. 28, 5, p. 2881-2889Research output: Contribution to journal › Journal article › Research › peer-review
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Drug formulations based on self-assembled liquid crystalline nanostructures
Yaghmur, Anan, Østergaard, Jesper, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Rappolt, M., 2014, Liposomes, lipid bilayers and model membranes: From basic research to application. Pabst, G., Kucerka, N., Nieh, M-P. & Katsaras, J. (eds.). Boca Raton: CRC Press, p. 341-360Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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In situ characterization of lipidic bupivacaine-loaded formulations
Yaghmur, Anan, Larsen, Susan Weng, Schmitt, M., Østergaard, Jesper, Larsen, C. S., Jensen, H., Urtti, A. & Rappolt, M., 2011, In: Soft Matter. 7, p. 8291-8295Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells
Yang, L., Fawcett, J. P., Østergaard, Jesper, Zhang, H. & Tucker, I. G., 2012, In: Molecular Pharmaceutics. 9, 1, p. 29-36Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of bile salts on propranolol distribution into liposomes studied by capillary electrophoresis
Yang, L., Tucker, I. G. & Østergaard, Jesper, 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 56, p. 553-559Research output: Contribution to journal › Journal article › Research › peer-review
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UV-imaging visulaliserer frigivelse af lægemiddelstoffer
Ye, F., Meng-Lund, E., Yaghmur, Anan, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2010, In: Lægemiddelforskning. 2010, p. 46-48Research output: Contribution to journal › Journal article › Communication
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Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix
Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78Research output: Contribution to journal › Journal article › Research › peer-review
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Drug release into hydrogel-based subcutaneous surrogates studied by UV imaging
Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 71, p. 27-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery
Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction of Amino Acid and Dipeptide beta-Naphthylamide Derivatives with Hyaluronic Acid and Human Serum Albumin Studied by Capillary Electrophoresis Frontal Analysis
Ye, F., Xie, Y., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, Jan 2013, In: Chromatographia. 76, 1-2, p. 49-57Research output: Contribution to journal › Journal article › Research › peer-review
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Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis
Ye, F., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. S. & Østergaard, Jesper, 2012, In: Journal of Pharmaceutical and Biomedical Analysis. 61, p. 176-183Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels
Ye, F., Yaghmur, Anan, Jensen, H., Larsen, Susan Weng, Larsen, C. & Østergaard, Jesper, 17 Jul 2011, In: European Journal of Pharmaceutical Sciences. 43, 4, p. 236-243Research output: Contribution to journal › Journal article › Research › peer-review
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Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, Jesper & Fotaki, N., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis
Zhuang, G., Poulsen, N. N., Petersen, Nickolaj J., Østergaard, Jesper & Jensen, H., 2 Sep 2013, 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. p. 1054-1057 4 p. 6559903Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication
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Use of correction factors in mobility shift affinity capillary electrophoresis for weak analyte - ligand interactions
Østergaard, Jesper, Jensen, H. & Holm, R., 2009, In: Journal of Separation Science. 32, 10, p. 1712-1721Research output: Contribution to journal › Journal article › Research › peer-review
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UV imaging for in vitro dissolution and release studies: Initial experiences
Østergaard, Jesper, Lenke, J., Jensen, S. S., Sun, Y. & Ye, F., 2014, In: Dissolution Technologies. 21, 4, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time UV imaging of nicotin release from transdermal patch
Østergaard, Jesper, Meng-Lund, E., Larsen, Susan Weng, Larsen, C. S., Petersson, K., Lenke, J. & Jensen, H., 2010, In: Pharmaceutical Research. 27, p. 2614-2623Research output: Contribution to journal › Journal article › Research › peer-review
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Bioreversible derivatives of phenol 1: the role of human serum albumin as related to the stability and binding properties of carbonate esters with fatty acid-like structures in aqueous solution and biological media
Østergaard, Jesper & Larsen, C. S., 2007, In: Molecules. 12, 10, p. 2380-2395Research output: Contribution to journal › Journal article › Research › peer-review
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Ghrelin-liposome interactions: Characterization of liposomal formulations of an acylated 28-amino acid peptide using CE
Østergaard, Jesper & Møller, E. H., 2010, In: Electrophoresis. 31, 2, p. 339-345Research output: Contribution to journal › Journal article › Research › peer-review
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UV imaging in pharmaceutical analysis
Østergaard, Jesper, 5 Jan 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 147, p. 140-148Research output: Contribution to journal › Review › Research › peer-review
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Binding of low-molecular-weight cationic ligands to chondroitin sulfate as studied by capillary electrophoresis frontal analysis
Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. R. & Larsen, C. S., 2009, In: Open Analytical Chemistry Journal. 3, p. 16-21Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous evaluation of ligand binding properies and protein size by electrophoresis and taylor dispersion in capillaries
Østergaard, Jesper & Jensen, H., 2009, In: Analytical Chemistry. 81, 20, p. 8644-8648Research output: Contribution to journal › Journal article › Research › peer-review
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Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar
Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29Research output: Contribution to journal › Journal article › Research
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Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis
Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324Research output: Contribution to journal › Journal article › Research › peer-review
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Application of retention factors in affinity electrokinetic chromatography and capíllary electrophoresis
Østergaard, Jesper, 2007, In: Analytical Sciences. 23, 4, p. 489-492Research output: Contribution to journal › Journal article › Research › peer-review
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Affinity capillary electrophoresis method for investigation of bile salts complexation with sulfobutyl ether-ß-cyclodextrin
Østergaard, Jesper, Jensen, H. & Holm, R., 2012, In: Journal of Separation Science. 35, 20, p. 2764-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioreversible derivatives of phenol. 2. Reactivity of carbonoate esters with fatty acid-like structures towards hydrolysis in aqueous solutions
Østergaard, Jesper & Larsen, C. S., 2007, In: Molecules. 12, 10, p. 2396-2412Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
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