Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

Publication year:
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101 - 150 out of 291Page size: 50
  1. 2016

  2. Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking.

    Thanki, K., Geyer, A., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Ogris, M., Nielsen, Hanne Mørck & Foged, C., 2016.

    Research output: Contribution to conference › Poster › Research

  3. Published

    Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

    Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection

    Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Soft hydrogels interpenetrating silicone – a polymer network for drug releasing medical devices

    Steffensen, S. L., Merete H., V., Møller, E. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2016, In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 104, 2, p. 402-410 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2015
  7. Published

    Antimicrobial activity of GN peptides and their mode of action

    Godballe, T., Mojsoska, B., Nielsen, Hanne Mørck & Jenssen, H., 13 Dec 2015, In: Biopolymers. 106, 2, p. 172–183 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bioactive protein-based nanofibers interact with intestinal biological components resulting in transepithelial permeation of a therapeutic protein

    Stephansen, K., García-Díaz, M., Jessen, F., Chronakis, I. S. & Nielsen, Hanne Mørck, 10 Nov 2015, In: International Journal of Pharmaceutics. 495, 1, p. 58-66 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation

    Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hyaluronic Acid-Based Nanogels Produced by Microfluidics-Facilitated Self-Assembly Improves the Safety Profile of the Cationic Host Defense Peptide Novicidin

    Water, J. J., Kim, Y., Maltesen, M. J., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, Aug 2015, In: Pharmaceutical Research. 32, 8, p. 2727-35 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Conjugation of a cell-penetrating peptide to parathyroid hormone affects its structure, potency, and transepithelial permeation

    Kristensen, Mie, de Groot, A. M., Berthelsen, J., Franzyk, Henrik, Sijts, A. & Nielsen, Hanne Mørck, 18 Mar 2015, In: Bioconjugate Chemistry. 26, p. 477-488 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Mucus as a Barrier to Drug Delivery: Understanding and Mimicking the Barrier Properties

    Bøgh, M. & Nielsen, Hanne Mørck, Mar 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 3, p. 179-186 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells

    Water, J. J., Smart, S., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 18 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 65-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin

    Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    End Group Modification: Efficient Tool for Improving Activity of Antimicrobial Peptide Analogues towards Gram-Positive Bacteria

    Jahnsen, R. O., Sandberg-Schaal, A., Frimodt-Møller, N., Nielsen, Hanne Mørck & Franzyk, Henrik, 23 Jan 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 95, Part A, p. 40–46 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Three-Dimensional Printing of Drug-Eluting Implants: Preparation of an Antimicrobial Polylactide Feedstock Material

    Water, J. J., Bohr, A., Bøtker, Johan Peter, Aho, J., Sandler, N., Nielsen, Hanne Mørck & Rantanen, Jukka, 15 Jan 2015, In: Journal of Pharmaceutical Sciences. p. 1099–1107 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

    Christophersen, P. C., Birch, D., Saarinen, J., Isomäki, A., Nielsen, Hanne Mørck, Yang, Mingshi, Strachan, C. J. & Mu, Huiling, 10 Jan 2015, In: Journal of Controlled Release. 197, p. 111-120 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Carrier peptide-mediated transepithelial permeation of biopharmaceuticals: Effect of co-administration versus direct conjugation

    Kristensen, Mie & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  20. Published

    Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

    Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro

    Rønholt, Stine, Kristensen, Mie & Nielsen, Hanne Mørck, 2015, Cell-penetrating peptides : Methods and Protocols. Langel, Ü. (ed.). Vol. 1324. p. 261-277 17 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro

    Rønholt, Stine, Kristensen, Mie & Nielsen, Hanne Mørck, 2015, In: Methods in Molecular Biology. 1324, p. 261-277 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

    Christophersen, P. C., Fano, M., Saaby, Lasse, Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2015, In: Current Pharmaceutical Design. 21, 19, p. 2611-28 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, D., Franzyk, H. & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  26. Published

    Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  27. Published

    Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites

    Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

    Kristensen, Mie, Franzyk, Henrik, Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, Vito & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Penetratin-Mediated Transepithelial Insulin Permeation: Importance of Cationic Residues and pH for Complexation and Permeation

    Kristensen, M., Franzyk, H., Klausen, M. T., Iversen, A., Bahnsen, J. S., Skyggebjerg, R. B., Foderà, V. & Nielsen, Hanne Mørck, 2015, In: A A P S Journal. 17, 5, p. 1200-1209 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Penetratin-mediated transepithelial insulin pemeation: Importance of complexation?

    Kristensen, Mie, Foderà, Vito & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  31. Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers

    Kristensen, M. & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  32. Published

    Reversible tight junction modulation using an enterotoxin-derived peptide as enhancer for delivery of biopharmaceuticals across biobarriers

    Kristensen, Mie & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  33. Published

    Surface coating of siRNA-peptidomimetic nano-self-assemblies with anionic lipid bilayers: Enhanced gene silencing and reduced adversed effects in vitro

    Zeng, X., de Groot, A. M., Sijts, A., Blenke, E. O., Colombo, S., van Eden, W., Franzyk, Henrik, Nielsen, Hanne Mørck & Foged, Camilla, 2015, In: Nanoscale. 7, 46, p. 19687-19698 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices

    Steffensen, S. L., Merete H., V., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 305-311

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2014
  36. Published

    Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading

    Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Epithelial permeation and absorption mechanisms of biopharmaceuticals

    Nielsen, Hanne Mørck, 1 Oct 2014, Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies. Springer US, Vol. 9781461495246. p. 99-122 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  38. Published

    The surface charge of liposomal adjuvants is decisive for their interactions with the Calu-3 and A549 airway epithelial cell culture models

    Ingvarsson, P. T., Rasmussen, I. S., Viaene, M., Irlik, P. J., Nielsen, Hanne Mørck & Foged, Camilla, Aug 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 87, 3, p. 480-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

    Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, Hanne Mørck & Hansen, P. R., 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  41. Published

    AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Nielsen, Hanne Mørck & Hansen, Paul Robert, 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  42. Published

    Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

    Jahnsen, R. D., Sandberg-Schaal, A., Vissing, K. J., Nielsen, Hanne Mørck, Frimodt-Møller, N. & Franzyk, Henrik, 20 Mar 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2864-2873

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

    Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Property profiling of biosimilar mucus in a novel mucus-containing in vitro model for assessment of intestinal drug absorption

    Bøgh, M., Baldursdóttir, S. G., Mullertz, Anette & Nielsen, Hanne Mørck, 8 Jan 2014, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 87, p. 227-235 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Characterization of PTH-CPP fusion peptides for oral delivery

    Kristensen, Mie, Berthelsen, J. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  46. Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

    Water, J. J., Maltesen, M. J., Foged, C., Franzyk, H. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  47. Published

    Improving the safety profile of an antimicrobial peptide: Self-assembly into hydrogel nanoparticles using microfluidics

    Water, J. J., Maltesen, M. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  48. Published

    Parathyroid hormone coupled to cell-penetrating peptides for oral delivery

    Kristensen, Mie & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  49. Silicone embedded nanogels for prolonged resistance against biofilm formation

    Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, H. & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  50. Published

    Silicone embedded nanogels for prolonged resistance against biofilm formation

    Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  51. Published

    Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

    Christophersen, P., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  52. Trilaurin diminishes food effect on the release of desmopressin from solid lipid microparticles

    Christophersen, P., Vaghela, D., Müllertz, A., Yang, M., Nielsen, Hanne Mørck & Mu, H., 2014.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  53. 2013
  54. Published

    Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement

    Sander, C., Nielsen, Hanne Mørck & Jacobsen, Jette, 31 Dec 2013, In: International Journal of Pharmaceutics. 458, 2, p. 254-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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