Christian Janfelt

Christian Janfelt

Associate Professor - Promotion Programme


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  1. Accepted/In press

    Oral Squamous Cell Carcinoma Lipid Evaluation in Gingiva Tissue Stored in TRIzol via Shotgun Lipidomics and MALDI Mass Spectrometry Imaging

    Bernardo, R. A., de Oliveira Júnior, C. I., Roque, J. V., Costa, N. D. L., Roriz, V. M., Sorgi, C. A., Janfelt, Christian, Vaz, B. G. & Chaves, A. R., 2023, (Accepted/In press) In: Journal of Proteome Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    In vivo dermal delivery of bleomycin with electronic pneumatic injection: drug visualization and quantification with mass spectrometry

    Bik, L., van Doorn, M., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Olesen, U. H., Hædersdal, Merete, Lerche, Catharina Margrethe & Hendel, K., 2022, In: Expert Opinion on Drug Delivery. 19, 2, p. 213-219

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Mass spectrometry imaging of plant metabolites – principles and possibilities

    Bjarnholt, Nanna, Li, B., D'Alvise, J. & Janfelt, Christian, 2014, In: Natural Product Reports. 31, 6, p. 818-837 20 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Detection of follicular transport of lidocaine and metabolism in adipose tissue in pig ear skin by DESI mass spectrometry imaging

    D'Alvise, J., Mortensen, R., Hansen, S. H. & Janfelt, Christian, Jun 2014, In: Analytical and Bioanalytical Chemistry. 406, 15, p. 3735-42 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Visualisation of penetration of topical antifungal drug substances through mycosis-infected nails by matrix-assisted laser desorption ionisation mass spectrometry imaging

    Endringer Pinto, F., Bagger, C., Kunze, G., Joly-Tonetti, N., Thenot, J., Osman-Ponchet, H. & Janfelt, Christian, 2020, In: Mycoses. 63, 8, p. 869-875 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars: A blinded randomized controlled trial

    Erlendsson, A. M., Rosenberg, L. K., Lerche, Catharina Margrethe, Togsverd-Bo, K., Wiegell, Stine Regin, Karmisholt, Katrine Elisabeth, Philipsen, P. A., Hansen, Anders Christian Nørgaard, Janfelt, Christian, Holmes, J., Rossi, A. & Hædersdal, Merete, 2022, In: Lasers in Surgery and Medicine. 54, 5, p. 663-671

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Fast and direct screening of polyaromatic hydrocarbon (PAH)-contaminated sand using a miniaturized membrane inlet mass spectrometer (mini-MIMS)

    Frandsen, H., Janfelt, Christian & Lauritsen, F. R., 2007, In: Rapid Communications in Mass Spectrometry. 21, p. 1574-1578 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin

    Frick, Karen Michiko, Lorensen, Marcus Daniel B B, Esteban, E., Pasha, A., Schulz, Alexander, Provart, N. J., Janfelt, Christian, Nour-Eldin, Hussam Hassan & Geu-Flores, Fernando, 2023, bioRxiv, 18 p.

    Research output: Working paper › Preprint › Research

  12. Published

    The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia

    Gallage, N. J., Jørgensen, Kirsten, Janfelt, Christian, Nielsen, A. J. Z., Naake, T., Dunski, E., Dalsten, L., Grisoni, M. & Møller, Birger Lindberg, 2018, In: Plant and Cell Physiology. 59, 2, p. 304-318 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Mass spectrometry imaging of oligosaccharides following in situ enzymatic treatment of maize kernels

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2022, In: Carbohydrate Polymers. 275, 10 p., 118693.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Variation in oligosaccharide profiles observed with AP-MALDI in different regions of maize kernels after treatment with xylanases

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2023, In: Journal of Cereal Science. 109, 10 p., 103586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Mass spectrometry imaging in drug distribution and drug metabolism studies: Principles, applications and perspectives

    Granborg, J. R., Handler, A. M. & Janfelt, Christian, 2022, In: Trends in Analytical Chemistry. 146, 13 p., 116482.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface

    Hall-Andersen, J., Kaasgaard, S. G. & Janfelt, Christian, Mar 2018, In: Chemistry and Physics of Lipids. 211, p. 100-106

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    MALDI mass spectrometry imaging as a complementary analytical method for improved skin distribution analysis of drug molecule and excipients

    Handler, A. M., Fallah, M., Just Pedersen, A., Pommergaard Pedersen, G., Troensegaard Nielsen, K. & Janfelt, Christian, 2020, In: International Journal of Pharmaceutics. 590, 119949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Quantitative MALDI mass spectrometry imaging for exploring cutaneous drug delivery of tofacitinib in human skin

    Handler, A. M., Pedersen, G. P., Nielsen, K. T., Janfelt, Christian, Pedersen, A. J. & Clench, M. R., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging

    Handler, A. M., Eirefelt, S., Lambert, M., Johansson, F., Hollesen Schefe, L., Knudsen, N. Ø., Bodenlenz, M., Birngruber, T., Sinner, F., Eriksson, A. H., Pedersen, G. P., Janfelt, Christian & Troensegaard Nielsen, K., 2021, In: Molecular Pharmaceutics. 18, 8, p. 3063-3072

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Aspects of Quantitation in Mass Spectrometry Imaging Investigated on Cryo-Sections of Spiked Tissue Homogenates

    Hansen, H. T. & Janfelt, Christian, 2016, In: Analytical Chemistry. 88, 23, p. 11513−11520 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa

    Hansen, S. E., Marxen, E., Janfelt, Christian & Jacobsen, Jette, Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 250-257

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging

    Hendel, K., Hansen, Anders Christian Nørgaard, Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, Christian, Olesen, U. H., Hædersdal, Merete & Lerche, Catharina Margrethe, 1 Jan 2021, In: Drug Delivery. 28, 1, p. 1141-1149 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

    Hendel, K. K., Bagger, C., Olesen, U. H., Janfelt, Christian, Hansen, S. H., Hædersdal, Merete & Lerche, C. M., Dec 2019, In: Drug Delivery. 26, 1, p. 244-251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Tissue distribution and metabolic profiling of cyclosporine (CsA) in mouse and rat investigated by DESI and MALDI mass spectrometry imaging (MSI) of whole-body and single organ cryo-sections

    Holm, N. B., Deryabina, M., Knudsen, C. B. & Janfelt, Christian, 2022, In: Analytical and Bioanalytical Chemistry. 414, p. 7167–7177

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

    Jacobsen, S. C., Speth, N. R., Xiong, M., Herth, Matthias Manfred, Kristensen, Jesper Langgaard, Palner, M. & Janfelt, Christian, 2021, In: Molecular Imaging and Biology. 23, p. 676–685

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Kan analyselaboratoriet flyttes i felten?

    Janfelt, Christian & Lauritsen, F. R., 2008, In: LMFK-Bladet. 1, p. 31-34 4 p.

    Research output: Contribution to journal › Journal article › Commissioned

  28. Published

    Billeddannende massespektrometri

    Janfelt, Christian, D'Alvise, J., Li, B. & Hansen, S. H., 2012, In: Dansk Kemi. 93, 6/7, p. 12-14 3 p.

    Research output: Contribution to journal › Journal article › Communication

  29. Published

    Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012, In: F A S E B Journal. 26, 6, p. 2667-2673

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Portable electrospray ionization mass spectrometry (ESI-MS) for analysis of contaminants in the field

    Janfelt, Christian, Græsbøll, R. & Lauritsen, F. R., 2012, In: International Journal of Environmental Analytical Chemistry. 92, 4, p. 397–404 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Method for Quantification of Chemicals in a Pollution Plume Using a Moving Membrane-Based Sensor Exemplified by Mass Spectrometry

    Janfelt, Christian, Lauritsen, F. R., Toler, S. K., Bell, R. J. & Short, R. T., 2007, In: Analytical Chemistry. 79, p. 5336-5342 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Displaced dual-mode imaging with desorption electrospray ionization for simultaneous mass spectrometry imaging in both polarities and with several scan modes

    Janfelt, Christian, Wellner, N., Hansen, Harald S. & Hansen, S. H., Mar 2013, In: Journal of Mass Spectrometry. 48, 3, p. 361-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Billeddannende massespektrometri til analyse af vævsprøver

    Janfelt, Christian, Wellner, N., D'Alvise, J. & Hansen, S. H., 2012, In: Dansk Kemi. 93, 8, p. 20-23

    Research output: Contribution to journal › Journal article › Research

  34. Mass spectra of proteins and other biomolecules recorded using a handheld instrument

    Janfelt, Christian, Talaty, N., Mulligan C., C., Keil, A., Quyang, Z. & Cooks, R. G., 2008, In: International Journal of Mass Spectrometry. 278, 2-3, p. 166-169

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Ambient mass spectrometry imaging: a comparison of desorption ionization by sonic spray and electrospray

    Janfelt, Christian & Nørgaard, A. W., Oct 2012, In: Journal of The American Society for Mass Spectrometry. 23, 10, p. 1670-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  37. Published

    Characterization of a capillary spray cell for easy analysis of extracts of biological samples

    Janfelt, Christian & Lauritsen, F. R., 2011, In: International Journal of Mass Spectrometry. 299, p. 178-183

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Characterization and optimization of membrane inlets for a miniature ion trap mass spectrometer operating at a high background pressure of humid air

    Janfelt, Christian, Graesboll, R. & Lauritsen, F. R., 2008, In: International Journal of Mass Spectrometry. 276, p. 17-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Imaging of plant materials using indirect desorption electrospray ionization mass spectrometry

    Janfelt, Christian, 2015, Mass Spectrometry Imaging of Small Molecules. He, L. (ed.). Humana Press, Vol. 1203. p. 91-7 7 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  40. Published

    Indirect DESI imaging of secondary metabolites in plant material

    Janfelt, Christian, Thunig, U. J. C., Li, B. & Hansen, S. H., 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  41. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In: Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  42. The magnitude of pseudo-potential errors for density functional calculations

    Janfelt, Christian & Jensen, F., 2005, In: Chemical Physics Letters. 412, p. 501-503 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Characterization of a mini membrane inlet mass spectrometer for on-site detection of contaminants in both aqueous and liquid organic samples

    Janfelt, Christian, Frandsen, H. & Lauritsen, F. R., 2006, In: Rapid Communications in Mass Spectrometry. 20, p. 1441–1446 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Liquid-Phase MicroExtraction coupled to Desorption Electrospray Ionization Mass Spectrometry in pharmaceutical analysis

    Janfelt, Christian, Thunig, U. J. C., Pedersen-Bjergaard, Stig & Hansen, S. H., 2009.

    Research output: Contribution to conference › Poster › Research

  45. The magnitude of pseudo-potential errors for bond distances and vibrational frequencies

    Jensen, F. & Janfelt, Christian, 2005, In: Chemical Physics Letters. 412, p. 12-15 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Visualization of penetration of topical antifungal drug substances through mycosis-infected nails by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI)

    Joly-Tonetti, N., Pinto, F. E., Bagger, C., Osman-Ponchet, H. & Janfelt, Christian, 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. AB191-AB191 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study

    Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    DESI-MS imaging of metabolites in various plant materials – a matter of sample preparation

    Kato, L., Rook, F., Møller, Birger Lindberg, Hansen, S. H. & Janfelt, Christian, 2015.

    Research output: Contribution to conference › Poster › Research

  49. Published

    The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging

    Kato, L., Moraes, A. P., de Oliveira, C. M. A., Vaz, B. G., de Almeida Gonçalves, L., E Silva, E. C. & Janfelt, Christian, 2018, In: Phytochemical Analysis. 29, p. 69-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Ambient Mass Spectrometry with a Handheld Mass Spectrometer at High Pressure

    Keil, A., Talaty, N., Janfelt, Christian, Noll, R. J., Gao, L., Ouyang, Z. & Cooks, R. G., 2007, In: Analytical Chemistry. 79, p. 7734-7739 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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