Christian Janfelt
Associate Professor - Promotion Programme
Toxicology and Drug Metabolism
Universitetsparken 2
2100 København Ø
- Published
Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine
Thunig, J., Flø, L., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2012, In: Rapid Communications in Massspectrometry. 26, 2, p. 133-140Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface
Hall-Andersen, J., Kaasgaard, S. G. & Janfelt, Christian, Mar 2018, In: Chemistry and Physics of Lipids. 211, p. 100-106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MALDI mass spectrometry imaging as a complementary analytical method for improved skin distribution analysis of drug molecule and excipients
Handler, A. M., Fallah, M., Just Pedersen, A., Pommergaard Pedersen, G., Troensegaard Nielsen, K. & Janfelt, Christian, 2020, In: International Journal of Pharmaceutics. 590, 119949.Research output: Contribution to journal › Journal article › Research › peer-review
Mass spectra of proteins and other biomolecules recorded using a handheld instrument
Janfelt, Christian, Talaty, N., Mulligan C., C., Keil, A., Quyang, Z. & Cooks, R. G., 2008, In: International Journal of Mass Spectrometry. 278, 2-3, p. 166-169Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometry imaging in drug distribution and drug metabolism studies: Principles, applications and perspectives
Granborg, J. R., Handler, A. M. & Janfelt, Christian, 2022, In: Trends in Analytical Chemistry. 146, 13 p., 116482.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia
Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometry imaging of oligosaccharides following in situ enzymatic treatment of maize kernels
Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2022, In: Carbohydrate Polymers. 275, 10 p., 118693.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometry imaging of plant metabolites – principles and possibilities
Bjarnholt, Nanna, Li, B., D'Alvise, J. & Janfelt, Christian, 2014, In: Natural Product Reports. 31, 6, p. 818-837 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv
Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In: Lægemiddelforskning. 2011, p. 10-12Research output: Contribution to journal › Journal article › Communication
- Published
Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination
Montini, L., Crocoll, C., Gleadow, R. M., Motawia, M. S., Janfelt, Christian & Bjarnholt, Nanna, 2020, In: Plant Physiology. 183, 3, p. 925-942 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Method for Quantification of Chemicals in a Pollution Plume Using a Moving Membrane-Based Sensor Exemplified by Mass Spectrometry
Janfelt, Christian, Lauritsen, F. R., Toler, S. K., Bell, R. J. & Short, R. T., 2007, In: Analytical Chemistry. 79, p. 5336-5342 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging
Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-acylation of phosphatidylethanolamine and its biological functions in mammals
Wellner, N., Diep, T. A., Janfelt, Christian & Hansen, Harald S., Mar 2013, In: BBA General Subjects. 1831, 3, p. 652-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural products in Glycyrrhiza glabra (licorice) rhizome imaged at the cellular level by atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry imaging
Li, B., Bhandari, D. R., Janfelt, Christian, Römpp, A. & Spengler, B., Oct 2014, In: Plant Journal. 80, 1, p. 161-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nebulization ionization and desorption ionization analysis of reactive organofunctionalized silanes in nanofilm products
Nørgaard, A. W., Janfelt, Christian, Benassi, M., Wolkoff, P. & Lauritsen, F. R., 2011, In: Journal of Mass Spectrometry. 46, 4, p. 402-410Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On-line monitoring of VOC emissions from nanofilm coating products using a handheld membrane inlet mass spectrometer
Nørgaard, A. W., Janfelt, Christian, Wolkoff, P., Jensen, K. A. & Lauritsen, F. R., 2008.Research output: Contribution to conference › Poster › Research
- Accepted/In press
Oral Squamous Cell Carcinoma Lipid Evaluation in Gingiva Tissue Stored in TRIzol via Shotgun Lipidomics and MALDI Mass Spectrometry Imaging
Bernardo, R. A., de Oliveira Júnior, C. I., Roque, J. V., Costa, N. D. L., Roriz, V. M., Sorgi, C. A., Janfelt, Christian, Vaz, B. G. & Chaves, A. R., 2023, (Accepted/In press) In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice
Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging
Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Portable electrospray ionization mass spectrometry (ESI-MS) for analysis of contaminants in the field
Janfelt, Christian, Græsbøll, R. & Lauritsen, F. R., 2012, In: International Journal of Environmental Analytical Chemistry. 92, 4, p. 397–404 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative MALDI mass spectrometry imaging for exploring cutaneous drug delivery of tofacitinib in human skin
Handler, A. M., Pedersen, G. P., Nielsen, K. T., Janfelt, Christian, Pedersen, A. J. & Clench, M. R., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration
Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin
Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of VOCs and particles during use of nanofilm spray products
Nørgaard, A. W., Jensen, K. A., Janfelt, Christian, Lauritsen, F. R., Clausen, P. A. & Wolkoff, P., 2009, In: Environmental Science and Technology. 43, 20, p. 7824-7830 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice
Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models
Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging
Lorensen, Marcus Daniel B B, Bjarnholt, Nanna, St-Pierre, B., Heinicke, S., Courdavault, V., O'Connor, S. & Janfelt, Christian, 2023, In: Phytochemistry. 209, 15 p., 113620.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of an insect model for drug metabolism by Desorption Electrospray Ionization Mass Spectrometry Imaging
Olsen, L. R., Hansen, S. H. & Janfelt, Christian, Aug 2014.Research output: Contribution to conference › Poster › Research
- Published
The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids
Stander, E. A., Lehka, B., Carqueijeiro, I., Cuello, C., Hansson, F. G., Jansen, H. J., Dugé De Bernonville, T., Birer Williams, C., Vergès, V., Lezin, E., Lorensen, M. D. B. B., Dang, T. T., Oudin, A., Lanoue, A., Durand, M., Giglioli-Guivarc’h, N., Janfelt, C., Papon, N., Dirks, R. P., O’connor, S. E. & 3 others, , 2023, In: Communications Biology . 6, 1, 19 p., 1197.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging
Kato, L., Moraes, A. P., de Oliveira, C. M. A., Vaz, B. G., de Almeida Gonçalves, L., E Silva, E. C. & Janfelt, Christian, 2018, In: Phytochemical Analysis. 29, p. 69-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin
Frick, Karen Michiko, Lorensen, Marcus Daniel B B, Esteban, E., Pasha, A., Schulz, Alexander, Provart, N. J., Janfelt, Christian, Nour-Eldin, Hussam Hassan & Geu-Flores, Fernando, 2023, bioRxiv, 18 p.Research output: Working paper › Preprint › Research
- Published
The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier
Ozgür, Burak, Saaby, Lasse, Eneberg, E., Langthaler, K., Jacobsen, A., Janfelt, Christian, Badolo, L., Montanari, D. & Larsen, Birger Brodin, 22 Jun 2018.Research output: Contribution to conference › Poster › Research › peer-review
- Published
The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia
Gallage, N. J., Jørgensen, Kirsten, Janfelt, Christian, Nielsen, A. J. Z., Naake, T., Dunski, E., Dalsten, L., Grisoni, M. & Møller, Birger Lindberg, 2018, In: Plant and Cell Physiology. 59, 2, p. 304-318 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
The magnitude of pseudo-potential errors for bond distances and vibrational frequencies
Jensen, F. & Janfelt, Christian, 2005, In: Chemical Physics Letters. 412, p. 12-15 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
The magnitude of pseudo-potential errors for density functional calculations
Janfelt, Christian & Jensen, F., 2005, In: Chemical Physics Letters. 412, p. 501-503 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue distribution and metabolic profiling of cyclosporine (CsA) in mouse and rat investigated by DESI and MALDI mass spectrometry imaging (MSI) of whole-body and single organ cryo-sections
Holm, N. B., Deryabina, M., Knudsen, C. B. & Janfelt, Christian, 2022, In: Analytical and Bioanalytical Chemistry. 414, p. 7167–7177Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue-specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics
Loupit, G., Fonayet, J. V., Lorensen, Marcus Daniel B B, Franc, C., De Revel, G., Janfelt, Christian & Cookson, S. J., 2023, In: Plant Cell and Environment. 46, 12, p. 3871-3886Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Topically applied methotrexate is rapidly delivered into skin by fractional laser ablation
Taudorf, E. H., Lerche, C., Vissing, A., Philipsen, P. A., Hannibal, Jens, D'Alvise, U. J. C., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, 2015, In: Expert Opinion on Drug Delivery. 12, 7, p. 1059-1069 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in oligosaccharide profiles observed with AP-MALDI in different regions of maize kernels after treatment with xylanases
Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2023, In: Journal of Cereal Science. 109, 10 p., 103586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualisation of penetration of topical antifungal drug substances through mycosis-infected nails by matrix-assisted laser desorption ionisation mass spectrometry imaging
Endringer Pinto, F., Bagger, C., Kunze, G., Joly-Tonetti, N., Thenot, J., Osman-Ponchet, H. & Janfelt, Christian, 2020, In: Mycoses. 63, 8, p. 869-875 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia
Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012, In: F A S E B Journal. 26, 6, p. 2667-2673Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualization of penetration of topical antifungal drug substances through mycosis-infected nails by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI)
Joly-Tonetti, N., Pinto, F. E., Bagger, C., Osman-Ponchet, H. & Janfelt, Christian, 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. AB191-AB191 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery
Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging
Li, B., Baden, C. K., Hansen, N. K. K., Jørgensen, Kirsten, Kannangara, R. M., Bak, Søren, Takos, A. M., Rook, F., Hansen, S. H., Møller, Birger Lindberg, Janfelt, Christian & Bjarnholt, Nanna, 2013, In: Plant Journal. 74, 6, p. 1059-1071 74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging
Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8407
Most downloads
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The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
196
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The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
185
downloads
Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published