Christian Janfelt

Christian Janfelt

Associate Professor - Promotion Programme


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  1. Published

    Visualizing the Journey of Fenofibrate through the Rat Gastrointestinal Tract by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

    Strindberg, S., Plum, J., Bagger, C., Janfelt, Christian & Mullertz, Anette , 2021, In: Molecular Pharmaceutics. 18, 6, p. 2189–2197

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging

    Li, B., Baden, C. K., Hansen, N. K. K., Jørgensen, Kirsten, Kannangara, R. M., Bak, Søren, Takos, A. M., Rook, F., Hansen, S. H., Møller, Birger Lindberg, Janfelt, Christian & Bjarnholt, Nanna, 2013, In: Plant Journal. 74, 6, p. 1059-1071 74.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Visualization of penetration of topical antifungal drug substances through mycosis-infected nails by matrix assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI)

    Joly-Tonetti, N., Pinto, F. E., Bagger, C., Osman-Ponchet, H. & Janfelt, Christian, 2021, In: Journal of the American Academy of Dermatology. 85, 3, p. AB191-AB191 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  5. Published

    Visualization by mass spectrometry of 2-dimensional changes in rat brain lipids, including N-acylphosphatidylethanolamines, during neonatal brain ischemia

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012, In: F A S E B Journal. 26, 6, p. 2667-2673

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Visualisation of penetration of topical antifungal drug substances through mycosis-infected nails by matrix-assisted laser desorption ionisation mass spectrometry imaging

    Endringer Pinto, F., Bagger, C., Kunze, G., Joly-Tonetti, N., Thenot, J., Osman-Ponchet, H. & Janfelt, Christian, 2020, In: Mycoses. 63, 8, p. 869-875 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Variation in oligosaccharide profiles observed with AP-MALDI in different regions of maize kernels after treatment with xylanases

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2023, In: Journal of Cereal Science. 109, 10 p., 103586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Topically applied methotrexate is rapidly delivered into skin by fractional laser ablation

    Taudorf, E. H., Lerche, C., Vissing, A., Philipsen, P. A., Hannibal, Jens, D'Alvise, U. J. C., Hansen, S. H., Janfelt, Christian, Paasch, U., Anderson, R. R. & Hædersdal, Merete, 2015, In: Expert Opinion on Drug Delivery. 12, 7, p. 1059-1069 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Tissue-specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics

    Loupit, G., Fonayet, J. V., Lorensen, Marcus Daniel B B, Franc, C., De Revel, G., Janfelt, Christian & Cookson, S. J., 2023, In: Plant Cell and Environment. 46, 12, p. 3871-3886

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Tissue distribution and metabolic profiling of cyclosporine (CsA) in mouse and rat investigated by DESI and MALDI mass spectrometry imaging (MSI) of whole-body and single organ cryo-sections

    Holm, N. B., Deryabina, M., Knudsen, C. B. & Janfelt, Christian, 2022, In: Analytical and Bioanalytical Chemistry. 414, p. 7167–7177

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. The magnitude of pseudo-potential errors for density functional calculations

    Janfelt, Christian & Jensen, F., 2005, In: Chemical Physics Letters. 412, p. 501-503 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. The magnitude of pseudo-potential errors for bond distances and vibrational frequencies

    Jensen, F. & Janfelt, Christian, 2005, In: Chemical Physics Letters. 412, p. 12-15 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The intracellular localization of the vanillin biosynthetic machinery in pods of Vanilla planifolia

    Gallage, N. J., Jørgensen, Kirsten, Janfelt, Christian, Nielsen, A. J. Z., Naake, T., Dunski, E., Dalsten, L., Grisoni, M. & Møller, Birger Lindberg, 2018, In: Plant and Cell Physiology. 59, 2, p. 304-318 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier

    Ozgür, Burak, Saaby, Lasse, Eneberg, E., Langthaler, K., Jacobsen, A., Janfelt, Christian, Badolo, L., Montanari, D. & Larsen, Birger Brodin, 22 Jun 2018.

    Research output: Contribution to conference › Poster › Research › peer-review

  15. Published

    The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin

    Frick, Karen Michiko, Lorensen, Marcus Daniel B B, Esteban, E., Pasha, A., Schulz, Alexander, Provart, N. J., Janfelt, Christian, Nour-Eldin, Hussam Hassan & Geu-Flores, Fernando, 2023, bioRxiv, 18 p.

    Research output: Working paper › Preprint › Research

  16. Published

    The Spatial Distribution of Alkaloids in Psychotria prunifolia (Kunth) Steyerm and Palicourea coriacea (Cham.) K. Schum Leaves Analysed by Desorption Electrospray Ionisation Mass Spectrometry Imaging

    Kato, L., Moraes, A. P., de Oliveira, C. M. A., Vaz, B. G., de Almeida Gonçalves, L., E Silva, E. C. & Janfelt, Christian, 2018, In: Phytochemical Analysis. 29, p. 69-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids

    Stander, E. A., Lehka, B., Carqueijeiro, I., Cuello, C., Hansson, F. G., Jansen, H. J., Dugé De Bernonville, T., Birer Williams, C., Vergès, V., Lezin, E., Lorensen, M. D. B. B., Dang, T. T., Oudin, A., Lanoue, A., Durand, M., Giglioli-Guivarc’h, N., Janfelt, C., Papon, N., Dirks, R. P., O’connor, S. E. & 3 others, Jensen, M. K., Besseau, S. & Courdavault, V., 2023, In: Communications Biology . 6, 1, 19 p., 1197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Studies of an insect model for drug metabolism by Desorption Electrospray Ionization Mass Spectrometry Imaging

    Olsen, L. R., Hansen, S. H. & Janfelt, Christian, Aug 2014.

    Research output: Contribution to conference › Poster › Research

  19. Published

    Spatial localization of monoterpenoid indole alkaloids in Rauvolfia tetraphylla by high resolution mass spectrometry imaging

    Lorensen, Marcus Daniel B B, Bjarnholt, Nanna, St-Pierre, B., Heinicke, S., Courdavault, V., O'Connor, S. & Janfelt, Christian, 2023, In: Phytochemistry. 209, 15 p., 113620.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

    Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Release of VOCs and particles during use of nanofilm spray products

    Nørgaard, A. W., Jensen, K. A., Janfelt, Christian, Lauritsen, F. R., Clausen, P. A. & Wolkoff, P., 2009, In: Environmental Science and Technology. 43, 20, p. 7824-7830 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration

    Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Quantitative MALDI mass spectrometry imaging for exploring cutaneous drug delivery of tofacitinib in human skin

    Handler, A. M., Pedersen, G. P., Nielsen, K. T., Janfelt, Christian, Pedersen, A. J. & Clench, M. R., 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 159, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Portable electrospray ionization mass spectrometry (ESI-MS) for analysis of contaminants in the field

    Janfelt, Christian, Græsbøll, R. & Lauritsen, F. R., 2012, In: International Journal of Environmental Analytical Chemistry. 92, 4, p. 397–404 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

    Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Oral administration of quercetin and fisetin potentiates photocarcinogenesis in UVR-exposed hairless mice

    Pihl, Celina, Granborg, J. R., Pinto, F. E., Bjerring, P., Andersen, F., Janfelt, Christian, Hædersdal, Merete & Lerche, Catharina Margrethe, 2024, In: Phytomedicine Plus. 4, 2, 8 p., 100547.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Accepted/In press

    Oral Squamous Cell Carcinoma Lipid Evaluation in Gingiva Tissue Stored in TRIzol via Shotgun Lipidomics and MALDI Mass Spectrometry Imaging

    Bernardo, R. A., de Oliveira Júnior, C. I., Roque, J. V., Costa, N. D. L., Roriz, V. M., Sorgi, C. A., Janfelt, Christian, Vaz, B. G. & Chaves, A. R., 2023, (Accepted/In press) In: Journal of Proteome Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    On-line monitoring of VOC emissions from nanofilm coating products using a handheld membrane inlet mass spectrometer

    Nørgaard, A. W., Janfelt, Christian, Wolkoff, P., Jensen, K. A. & Lauritsen, F. R., 2008.

    Research output: Contribution to conference › Poster › Research

  31. Published

    Nebulization ionization and desorption ionization analysis of reactive organofunctionalized silanes in nanofilm products

    Nørgaard, A. W., Janfelt, Christian, Benassi, M., Wolkoff, P. & Lauritsen, F. R., 2011, In: Journal of Mass Spectrometry. 46, 4, p. 402-410

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Natural products in Glycyrrhiza glabra (licorice) rhizome imaged at the cellular level by atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry imaging

    Li, B., Bhandari, D. R., Janfelt, Christian, Römpp, A. & Spengler, B., Oct 2014, In: Plant Journal. 80, 1, p. 161-71 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    N-acylation of phosphatidylethanolamine and its biological functions in mammals

    Wellner, N., Diep, T. A., Janfelt, Christian & Hansen, Harald S., Mar 2013, In: BBA General Subjects. 1831, 3, p. 652-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Method for Quantification of Chemicals in a Pollution Plume Using a Moving Membrane-Based Sensor Exemplified by Mass Spectrometry

    Janfelt, Christian, Lauritsen, F. R., Toler, S. K., Bell, R. J. & Short, R. T., 2007, In: Analytical Chemistry. 79, p. 5336-5342 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging of Metabolites during Sorghum Germination

    Montini, L., Crocoll, C., Gleadow, R. M., Motawia, M. S., Janfelt, Christian & Bjarnholt, Nanna, 2020, In: Plant Physiology. 183, 3, p. 925-942 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In: Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  38. Published

    Mass spectrometry imaging of plant metabolites – principles and possibilities

    Bjarnholt, Nanna, Li, B., D'Alvise, J. & Janfelt, Christian, 2014, In: Natural Product Reports. 31, 6, p. 818-837 20 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Mass spectrometry imaging of oligosaccharides following in situ enzymatic treatment of maize kernels

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2022, In: Carbohydrate Polymers. 275, 10 p., 118693.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Mass spectrometry imaging of biomarker lipids for phagocytosis and signalling during focal cerebral ischaemia

    Nielsen, M. M. B., Lambertsen, K. L., Clausen, B. H., Meyer, M., Bhandari, D. R., Larsen, S. T., Poulsen, Steen Seier, Spengler, B., Janfelt, Christian & Hansen, Harald S., 22 Dec 2016, In: Scientific Reports. 6, p. 1-14 14 p., 39571.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Mass spectrometry imaging in drug distribution and drug metabolism studies: Principles, applications and perspectives

    Granborg, J. R., Handler, A. M. & Janfelt, Christian, 2022, In: Trends in Analytical Chemistry. 146, 13 p., 116482.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Mass spectra of proteins and other biomolecules recorded using a handheld instrument

    Janfelt, Christian, Talaty, N., Mulligan C., C., Keil, A., Quyang, Z. & Cooks, R. G., 2008, In: International Journal of Mass Spectrometry. 278, 2-3, p. 166-169

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    MALDI mass spectrometry imaging as a complementary analytical method for improved skin distribution analysis of drug molecule and excipients

    Handler, A. M., Fallah, M., Just Pedersen, A., Pommergaard Pedersen, G., Troensegaard Nielsen, K. & Janfelt, Christian, 2020, In: International Journal of Pharmaceutics. 590, 119949.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    MALDI imaging of enzymatic degradation of glycerides by lipase on textile surface

    Hall-Andersen, J., Kaasgaard, S. G. & Janfelt, Christian, Mar 2018, In: Chemistry and Physics of Lipids. 211, p. 100-106

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine

    Thunig, J., Flø, L., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2012, In: Rapid Communications in Massspectrometry. 26, 2, p. 133-140

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Liquid-Phase MicroExtraction coupled to Desorption Electrospray Ionization Mass Spectrometry in pharmaceutical analysis

    Janfelt, Christian, Thunig, U. J. C., Pedersen-Bjergaard, Stig & Hansen, S. H., 2009.

    Research output: Contribution to conference › Poster › Research

  47. Published

    Leaves of Cannabis sativa and their trichomes studied by DESI and MALDI mass spectrometry imaging for their contents of cannabinoids and flavonoids

    Lorensen, Marcus Daniel B B, Hayat, S. Y., Wellner, N., Bjarnholt, Nanna & Janfelt, Christian, 2023, In: Phytochemical Analysis. 34, 3, p. 269-279

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Kan analyselaboratoriet flyttes i felten?

    Janfelt, Christian & Lauritsen, F. R., 2008, In: LMFK-Bladet. 1, p. 31-34 4 p.

    Research output: Contribution to journal › Journal article › Commissioned

  49. Published

    Ischemia in neonatal rat brains analyzed by Desorption Electrospray Ionization Imaging mass spectrometry

    Janfelt, Christian, Wellner, N., Leger, P., Kokesch-Himmelreich, J., Hansen, S. H., Charriaut-Marlangue, C. & Hansen, Harald S., 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  50. Published

    Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

    Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

    Research output: Contribution to journal › Journal article › Research › peer-review

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