Camilla Foged

Camilla Foged

Professor

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    ORCID: 0000-0003-2812-5588

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    1. Published

      The supramolecular structure is decisive for the immunoactivity of a mycobacterial lipid in vitro.

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2014. 1 p.

      Research output: Contribution to conference › Poster › Research

    2. Published

      Pulmonary Administration of the Liposome-Based Adjuvant CAF01: Effect of Surface Charge on Mucosal Adjuvant Function

      Müllertz, O. A. O., Andersen, P., Christensen, D., Foged, Camilla & Thakur, A., 2023, In: Molecular Pharmaceutics. 20, 2, p. 953–970

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Biologiske lægemidler - fra molekyle til medicin

      Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14

      Research output: Contribution to journal › Journal article › Research

    4. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers

      Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    5. Published

      Immunity by formulation design: induction of high CD8+ T-cell responses by poly (I:C) incorporated into the CAF01 adjuvant via a double emulsion method

      Nordly, P. J., Rose, F., Christensen, D., Nielsen, Hanne Mørck, Andersen, P., Agger, E. M. & Foged, Camilla, 2011, In: Journal of Controlled Release. 150, 3, p. 307-317

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators

      Nordly, P. J., Foged, Camilla, Christensen, D., Lindenstrøm, T., Nielsen, Hanne Mørck & Agger, E., 2010.

      Research output: Contribution to conference › Poster › Research

    7. Published

      Innovativt nanopartikeldesign bag skræddersyede vacciner

      Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Lægemiddelforskning. p. 19-21

      Research output: Contribution to journal › Journal article › Research

    8. Published

      Incorporation of the TLR4 agonist monophosphoryl lipid A into the bilayer of DDA/DTDB liposomes : physico-chemical characterization and induction of CD8+ T-Cell responses in vivo

      Nordly, P. J., Agger, E. M., Andersen, P., Nielsen, Hanne Mørck & Foged, Camilla, 2011, In: Pharmaceutical Research. 28, 3, p. 553-562

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators

      Nordly, P. J., Madsen, H. B., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Expert Opinion on Drug Delivery. 6, 7, p. 1-16

      Research output: Contribution to journal › Review › Research

    10. Published

      A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes

      Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.

      Research output: Contribution to journal › Journal article › Research

    11. Published

      Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

      Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids

      Ongun, Melike, Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2022, Messenger RNA Therapeutics. Springer, p. 237-255 (RNA Technologies, Vol. 13).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    13. Published

      Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

      Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Malaria biomimetic for tumor targeted drug delivery

      Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

      Ragelle, H., Colombo, S., Pourcelle, V., Vanvarenberg, K., Vandermeulen, G., Bouzin, C., Marchand-Brynaert, J., Feron, O., Foged, Camilla & Préat, V., 10 Aug 2015, In: Journal of Controlled Release. 211, p. 1-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Transcutaneous immunization

      Rattanapak, T., Foged, Camilla & Hook, S., 2015, Subunit vaccine delivery. London: Springer, p. 347-369 23 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    17. Published

      Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein

      Rodrigues, L., Raftopoulos, K. N., Tandrup Schmidt, S., Schneider, F., Dietz, H., Rades, Thomas, Franzyk, Henrik, Pedersen, Anders Elm, Papadakis, C. M., Christensen, D., Winter, G., Foged, Camilla & Hubert, M., 10 Sep 2018, In: Journal of controlled release : official journal of the Controlled Release Society. 285, p. 12-22 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion antigen CTH522

      Rose, F., Erbo Wern, J., Gavins, F., Andersen, P., Follmann, F. & Foged, Camilla, Feb 2018, In: Journal of Controlled Release. 271, p. 88-97 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles

      Rose, F., Karlsen, K., Jensen, P. R., Jakobsen, R. U., Wood, G. K., Rand, Kasper Dyrberg, Godiksen, H., Andersen, P., Follmann, F. & Foged, Camilla, Jun 2018, In: Journal of Pharmaceutical Sciences. 107, 6, p. 1690-1700 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Temperature-Induced Self-Assembly of the Group B Streptococcus (GBS) Fusion Antigen GBS-NN

      Rose, F., Roovers, S., Fano, M., Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Hejnaes, K., Fischer, P. & Foged, Camilla, 2018, In: Molecular Pharmaceutics. 15, p. 2584-2593 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach

      Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Systematic investigation of the role of surfactant composition and choice of oil: Design of a nanoemulsion-based adjuvant inducing concomitant humoral and CD4+ T-cell responses

      Schmidt, S. T., Neustrup, M. A., Rønholt, Stine, Korsholm, K. S., Rades, Thomas, Andersen, P., Christensen, D. & Foged, Camilla, Aug 2017, In: Pharmaceutical Research. 34, 8, p. 1716-1727 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Induction of Cytotoxic T-Lymphocyte Responses Upon Subcutaneous Administration of a Subunit Vaccine Adjuvanted With an Emulsion Containing the Toll-Like Receptor 3 Ligand Poly(I:C)

      Schmidt, S. T., Pedersen, G. K., Neustrup, M. A., Korsholm, K. S., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 30 Apr 2018, In: Frontiers in Immunology. 9, 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile

      Schmidt, S. T., Khadke, S., Korsholm, K. S., Perrie, Y., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 26 Aug 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 239, p. 107-117 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

      Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration

      Tandrup Schmidt, S., Line Olsen, C., Franzyk, Henrik, Wørzner, K., Smith Korsholm, K., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, p. 29-39 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model

      Te Boekhorst, B. C. M., Jensen, L. B., Colombo, S., Varkouhi, A. K., Schiffelers, R. M., Lammers, T., Storm, G., Nielsen, Hanne Mørck, Strijkers, G. J., Foged, Camilla & Nicolay, K., 2012, In: Journal of controlled release : official journal of the Controlled Release Society. 161, 3, p. 772-80 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder

      Thakur, A., Ingvarsson, P. T., Schmidt, S. T., Rose, F., Andersen, P., Christensen, D. & Foged, Camilla, 31 May 2018, In: Vaccine. 36, 23, p. 3331-3339 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Nanoparticles for mucosal vaccine delivery

      Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Mozafari, M. (ed.). 1 ed. Elsevier

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    30. Published

      Nanoparticles for mucosal vaccine delivery

      Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Woodhead Publishing, p. 603-646 44 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    31. Published

      Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins

      Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles

      Thakur, A., Rose, F., Ansari, S. R., Koch, P., Martini, V., Ovesen, S. L., Quistorff, B., Maritim, S., Hyder, F., Andersen, Peter, Christensen, D., Mori, Yuki & Foged, Camilla, 2019, In: Molecular Pharmaceutics. 16, 11, p. 4725-4737 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF®01 for pulmonary immunization

      Thakur, A., Xu, Y., Cano-Garcia, G., Feng, S., Rose, F., Gerde, P., Andersen, Peter, Christensen, D. & Foged, Camilla, 2022, In: Frontiers in Drug Delivery. 2, 973599.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization

      Thakur, A., Rodríguez-Rodríguez, C., Saatchi, K., Rose, F., Esposito, T., Nosrati, Z., Andersen, P., Christensen, D., Häfeli, U. O. & Foged, Camilla, 2018, In: Frontiers in Immunology. 9, 21 p., 2825.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

      Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Application of a Quality-By-Design Approach to Optimise Lipid-Polymer Hybrid Nanoparticles Loaded with a Splice-Correction Antisense Oligonucleotide: Maximising Loading and Intracellular Delivery

      Thanki, K., Papai, S., Lokras, Abhijeet, Rose, F., Falkenberg, E., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 3, 37.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Efficient Pulmonary Delivery of siRNA Using Lipid-polymer Hybrid Nanoparticles (LPNs): A quality-by-design approach for highly systematic optimization of LPNs

      Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

      Research output: Contribution to conference › Poster › Research

    38. Published

      Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration

      Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Efficient Pulmonary Delivery of siRNA Using Lipid-Polymer Hybrid Nanoparticles (LPNs): Insights into Formulation, Transfection and In Vivo Biodistribution Using NIR-based Spatio-Temporal Tracking.

      Thanki, K., Geyer, A., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, Henrik, Ogris, M., Nielsen, Hanne Mørck & Foged, Camilla, 2016.

      Research output: Contribution to conference › Poster › Research

    40. Published

      Preparation, Characterization, and In Vitro Evaluation of Lipidoid-Polymer Hybrid Nanoparticles for siRNA Delivery to the Cytosol

      Thanki, K., Zeng, X. & Foged, Camilla, 2019, In: Methods in molecular biology (Clifton, N.J.). 1943, p. 141-152 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities

      Thanki, K., Blum, K. G., Thakur, A., Rose, F. & Foged, Camilla, Oct 2018, In: Therapeutic Delivery. 9, 10, p. 731-749 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Immune Reactions in the Delivery of RNA Interference-Based Therapeutics: Mechanisms and Opportunities

      Thanki, K., Falkenberg, E., Gangloff, M. & Foged, Camilla, 31 Aug 2018, Immune Effects of Biopharmaceuticals and Nanomedicine. Bawa, R., Szebeni, J. & Audette, G. (eds.). Pan Stanford, 32 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    43. Published

      Engineering of small interfering RNA-loaded lipidoid-poly(DL-lactic-co-glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design-based approach

      Thanki, K., Zeng, X., Justesen, S., Tejlmann, S., Falkenberg, E., Van Driessche, E., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 22-33 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

      Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, Foged, Camilla, 2018.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    45. Published

      Antiplasmodial and prehemolytic activities of alpha-peptide-beta-peptoid chimeras

      Vedel, L., Bonke, G., Foged, Camilla, Ziegler, H. L., Franzyk, Henrik, Jaroszewski, J. W. & Olsen, Christian Adam, 2007, In: ChemBioChem. 8, 15, p. 1781-1784 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells

      Vencken, S., Foged, Camilla, Ramsey, J. M., Sweeney, L., Cryan, S., MacLoughlin, R. J. & Greene, C. M., Apr 2019, In: ERJ Open Research. 5, 2, 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Opportunities and Challenges in the Delivery of mRNA-based Vaccines

      Wadhwa, A., Aljabbari, A., Lokras, Abhijeet, Foged, Camilla & Thakur, A., 28 Jan 2020, In: Pharmaceutics. 12, 2, 27 p., 102.

      Research output: Contribution to journal › Review › Research › peer-review

    48. Published

      Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

      Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Particle engineering technologies for improving the delivery of peptide and protein drugs

      Wan, F., Maltesen , M. J., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 355-363

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Critical solvent properties affecting the particle formation process and characteristics of celecoxib-loaded PLGA microparticles via spray-drying

      Wan, F., Bohr, A., Maltesen, M. J., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, Apr 2013, In: Pharmaceutical Research. 30, 4, p. 1065-1076

      Research output: Contribution to journal › Journal article › Research › peer-review

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