Birger Brodin Larsen

Birger Brodin Larsen

Professor


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  1. Published

    Ibuprofen is an inhibitor of hPEPT1: Implications for drug-drug interactions at the level of drug absorption

    Omkvist, D. H., Larsen, Birger Brodin & Nielsen, C. U., 2010.

    Research output: Contribution to conference › Poster › Research

  2. Published

    Affinity and translocation relationships via hPEPT1 of H-Xaa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs

    Omkvist, D. H., Trangbæk, D. J., Mildon, J., Paine, J. S., Larsen, Birger Brodin, Begtrup, M. & Nielsen, C. U., 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 2, p. 327-331

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The proton-coupled amino acid transporter hPAT1 is the main transporter involved in vigabatrin uptake in intestinal Caco-2 cells

    Nøhr, M. K., Hansen, S. H., Larsen, Birger Brodin, Holm, R. & Nielsen, C. U., 30 Nov 2012.

    Research output: Contribution to conference › Poster › Research

  4. Published

    The absorptive flux of the anti-epileptic drug substance vigabatrin is carrier-mediated across Caco-2 cell monolayers

    Nøhr, M. K., Hansen, S. H., Larsen, Birger Brodin, Holm, R. & Nielsen, C. U., 23 Jan 2014, In: European Journal of Pharmaceutical Sciences. 51, p. 1-10

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Vigabatrin absorption is mediated via the proton-coupled amino acid transporter PAT1 – in vitro and in vivo

    Nøhr, M. K., Juul, R. V., Hansen, S. H., Larsen, Birger Brodin, Holm, R., Kreilgaard, M. & Nielsen, C. U., 24 Jun 2013.

    Research output: Contribution to conference › Poster › Research

  6. Published

    Apicobasal transferrin receptor localization and trafficking in brain capillary endothelial cells

    Nielsen, S. S. E., Holst, M. R., Langthaler, Kristine, Bruun, E. H., Larsen, Birger Brodin & Nielsen, M. S., 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Basolateral peptid etransport in the human intestinal cell line Caco-2 is proton-coupled

    Nielsen, M. J., Nielsen, C. U. & Larsen, Birger Brodin, 2008. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  8. Published

    Transport characteristics of L-carnosine and the anticancer derivative 4-toluenesulfonylureido-carnosine in a human epithelial cell line

    Nielsen, C. U., Supuran, C. T., Scozzafava, A., Frøkjær, Sven, Steffansen, B. & Larsen, Birger Brodin, 2002, In: Pharmaceutical Research. 19, 9, p. 1337-44 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    GABA transport across the basolateral membrane of intestinal cells

    Nielsen, C. U., Carstensen, M. & Larsen, Birger Brodin, 2010. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  10. Published

    Carrier-mediated transport kinetics

    Nielsen, C. U., Steffansen, B. & Larsen, Birger Brodin, 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Pharmaceutical Press, p. 153-173

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  11. Published

    Absorptive transporters

    Nielsen, C. U., Steffansen, B. & Larsen, Birger Brodin, 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage from evaluation. Steffansen, B., Brodin, B. & Uhd Nielsen, C. (eds.). London: Pharmaceutical Press, p. 193-211 (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    Human peptide transporters: Therapeutic applications

    Nielsen, C. U., Larsen, Birger Brodin, Jørgensen, Flemming Steen, Frøkjær, Sven & Steffansen, B., 1 Sep 2002, In: Expert Opinion on Therapeutic Patents. 12, 9, p. 1329-1350 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Carrier-mediated ¿-aminobutyric acid transport across the basolateral membrane of human intestinal Caco-2 cell monolayers

    Nielsen, C. U., Carstensen, M. & Larsen, Birger Brodin, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 2, p. 458-462

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro

    Nielsen, C. U., Frølund, S. B., Abdulhadi, S., Sari, H., Langthaler, L., Nøhr, M. K., Kall, M. A., Larsen, Birger Brodin & Holm, R., Nov 2013, In: British Journal of Pharmacology. 170, 5, p. 1041-52 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Application of Cell Culture and Tissue Models for Assessing Drug Transport

    Nielsen, C. U. & Larsen, Birger Brodin, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer, p. 791-821 30 p. (Advances in Delivery Science and Technology; No. 1).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  16. Published

    The F28Y substitution in the human intestinal di/tri-peptide transporter hPEPT1, causes altered pH-dependency of Gly-Sar transport

    Nielsen, C. U., Krog, P., Anderlee, P., Sadeé, W. & Larsen, Birger Brodin, 2005.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  17. Published

    Recent advances in therapeutic applications of human transporters

    Nielsen, C. U., Våbenø, J., Andersen, R., Larsen, Birger Brodin & Steffansen, B., 2005, In: Expert Opinion on Therapeutic Patents. 15, 2, p. 153-166 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Efflux transporters

    Nielsen, C. U., Larsen, Birger Brodin & Steffansen, B., 2010, Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. Steffansen, B., Brodin, B. & Uhd Nielsen, C. (eds.). Pharmaceutical Press, p. 213-22

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  19. Published

    Carrier-mediated dipeptide transport in a human lung epithelial cell line, Calu-3

    Nielsen, C. U., Søndergaard, H. B. & Larsen, Birger Brodin, 2006. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  20. Published

    Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line

    Nielsen, C. U., Andersen, R., Larsen, Birger Brodin, Frøkjær, Sven, Taub, M. E. & Steffansen, B., 2001, In: Journal of Controlled Release. 76, 1-2, p. 129-38 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line

    Nielsen, C. U., Amstrup, J., Steffansen, B., Frøkjær, Sven & Larsen, Birger Brodin, 2001, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 281, 1, p. G191-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Di/tri-peptide transporters as drug delivery targets: regulation of transport under physiological and patho-physiological conditions

    Nielsen, C. U. & Larsen, Birger Brodin, 2003, In: Current Drug Targets. 4, 5, p. 373-88 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Model prodrugs for the intestinal oligopeptide transporter: model drug release in aqueous solution and in various biological media

    Nielsen, C. U., Andersen, R., Larsen, Birger Brodin, Frøkjær, Sven & Steffansen, B., 2001, In: Journal of Controlled Release. 73, 1, p. 21-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus

    Nielsen, A. K. R., Lilieholm-Røngren, L., Schmid, B., Holst, B., Larsen, Birger Brodin & Saaby, Lasse, 2024, In: Stem Cell Research. 76, 5 p., 103348.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Evidence for a Na+/Ca2+ exchange mechanism in frog skin epithelium

    Madsen, K. H., Larsen, Birger Brodin & Nielsen, Rasmus, 1999, In: Pflügers Archiv - European Journal of Physiology. 437, 2, p. 175-81 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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