Anette Müllertz
Professor
- 2014
- Published
Feasibility of Capsule Endoscopy for Direct Imaging of Drug Delivery Systems in the Fasted Upper-Gastrointestinal Tract
Pedersen, P. B., Bar-Shalom, Daniel, Baldursdottir, S., Vilmann, Peter & Mullertz, Anette , 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 2044-2053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Miniaturized approach for excipient selection during the development of oral solid dosage form
Raijada, D. K., Mullertz, Anette , Cornett, Claus, Munk, T., Møller-Sonnergaard, Jørn & Rantanen, Jukka, Mar 2014, In: Journal of Pharmaceutical Sciences. 103, 3, p. 900-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation
Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate
Thomas, N., Richter, K., Pedersen, T. B., Holm, R., Mullertz, Anette & Rades, Thomas, 2 Apr 2014, In: A A P S Journal. 16, 3, p. 539-549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa
Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour
Nielsen, L. H., Keller, S. S., Boisen, A., Mullertz, Anette & Rades, Thomas, Jun 2014, In: Drug Delivery and Translational Research. 4, 3, p. 268-74 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining stability and dissolution rate of amorphous drug formulations
Grohganz, Holger, Priemel, P. A., Löbmann, Korbinian, Nielsen, L. H., Laitinen, R., Mullertz, Anette , Van den Mooter, G. & Rades, Thomas, Jun 2014, In: Expert Opinion on Drug Delivery. 11, 6, p. 977-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs
Bergström, C. A. S., Holm, R., Jørgensen, S. A., Andersson, S. B. E., Artursson, P., Beato, S., Borde, A., Box, K., Brewster, M., Dressman, J., Feng, K., Halbert, G., Kostewicz, E., McAllister, M., Muenster, U., Thinnes, J., Taylor, R. & Mullertz, Anette , 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 173-99 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro models for the prediction of in vivo performance of oral dosage forms
Kostewicz, E. S., Abrahamsson, B., Brewster, M., Brouwers, J., Butler, J., Carlert, S., Dickinson, P. A., Dressman, J., Holm, R., Klein, S., Mann, J., McAllister, M., Minekus, M., Muenster, U., Mullertz, Anette , Verwei, M., Vertzoni, M., Weitschies, W. & Augustijns, P., 16 Jun 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 342-66 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems
Heshmati, N., Cheng, X., Dapat, E., Sassene, P., Eisenbrand, G., Fricker, G. & Mullertz, Anette , 24 Jun 2014, In: The Journal of pharmacy and pharmacology. 66, 11, p. 1567-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin
Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example
Berthelsen, R., Sjögren, E., Jacobsen, Jette, Kristensen, J., Holm, R., Abrahamsson, B. & Mullertz, Anette , 2 Jul 2014, In: International Journal of Pharmaceutics. 473, 1-2, p. 356-365 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system
Williams, H. D., Sassene, P., Kleberg, K., Calderone, M., Igonin, A., Jule, E., Vertommen, J., Blundell, R., Benameur, H., Mullertz, Anette , Porter, C. J. H., Pouton, C. W. & Communicated on Behalf of the LFCS Consortium, C. O. B. O. T. L. C., Aug 2014, In: Journal of Pharmaceutical Sciences. 103, 8, p. 2441-55 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-nanoemulsifying drug delivery systems for oral insulin delivery: In vitro and in vivo evaluations of enteric coating and drug loading
Li, P., Tan, A., Prestidge, C. A., Nielsen, Hanne Mørck & Mullertz, Anette , 30 Dec 2014, In: International Journal of Pharmaceutics. 477, 1-2, p. 390-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system
Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipophilic prodrugs of apomorphine I: Preparation, characterisation, and in vitro enzymatic hydrolysis in biorelevant media.
Borkar, N. N., Li, B., Holm, R., Håkansson, A., Mullertz, Anette , Yang, Mingshi & Mu, Huiling, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 89, p. 216-223 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Marine lipids and the bioavailability of omega-3 fatty acids
Mu, Huiling & Mullertz, Anette , 2015, In: Current Nutrition and Food Science. 11, 3, p. 177-187 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans
Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural features of colloidal species in the human fasted upper small intestine
Mullertz, Anette , Reppas, C., Psachoulias, D., Vertzoni, M. & Fatouros, D. G., Apr 2015, In: Journal of Pharmacy and Pharmacology. 67, 4, p. 486-492 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase
Bakala-N'Goma, J., Williams, H. D., Sassene, P. J., Kleberg, K., Calderone, M., Jannin, V., Igonin, A., Partheil, A., Marchaud, D., Jule, E., Vertommen, J., Maio, M., Blundell, R., Benameur, H., Mullertz, Anette , Pouton, C. W., Porter, C. J. H. & Carriere, F., Apr 2015, In: Pharmaceutical Research. 32, 4, p. 1279-1287 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilisation of amorphous furosemide increases the oral drug bioavailability in rats
Nielsen, L. H., Rades, Thomas & Mullertz, Anette , 25 Jul 2015, In: International Journal of Pharmaceutics. 490, 1-2, p. 334-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems
Mosgaard, M. D., Sassene, P., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Aug 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steric and interactive barrier properties of intestinal mucus elucidated by particle diffusion and peptide permeation
Bøgh, M., García-Díaz, M., Mullertz, Anette & Nielsen, Hanne Mørck, Sep 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, Part A, p. 136–143 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers
Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Digestion Models.
Berthelsen, R., Sassene, P., Rades, Thomas & Mullertz, Anette , 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Evaluating Oral Drug Delivery Systems: Dissolution Models.
Berthelsen, R., Mullertz, Anette & Rades, Thomas, 2016, Analytical Techniques in the Pharmaceutical Sciences. Springer, p. 753-771Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Rhamnogalacturonan-I based microcapsules for targeted drug release
Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract
Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS)
Michaelsen, M. H., Wasan, K. M., Sivak, O., Mullertz, Anette & Rades, Thomas, Jan 2016, In: The A A P S Journal. 18, 1, p. 180-186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution Model Development: Formulation Effects and Filter Complications
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , Feb 2016, In: Dissolution Technologies. 23, 1, p. 6-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction
Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine
Tran, T., Xi, X., Rades, Thomas & Mullertz, Anette , 11 Apr 2016, In: International Journal of Pharmaceutics. 502, 1-2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apomorphine and its esters: Differences in Caco-2 cell permeability and chylomicron affinity
Borkar, N., Chen, Z., Saaby, Lasse, Mullertz, Anette , Håkansson, A. E., Schönbeck, C., Yang, Mingshi, Holm, R. & Mu, Huiling, 6 Jun 2016, In: International Journal of Pharmaceutics. 509, 1-2, p. 499–506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Madsen, C. M., Boyd, B., Rades, Thomas & Mullertz, Anette , 25 Aug 2016, In: European Journal of Pharmaceutical Sciences. 91, p. 31-39 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of lipid-based drug delivery systems on the transport and uptake of insulin across Caco-2 Cell monolayers
Li, P., Nielsen, Hanne Mørck & Mullertz, Anette , Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2743-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interlaboratory validation of small-scale solubility and dissolution measurements of poorly water-soluble drugs
Andersson, S. B. E., Alvebratt, C., Bevernage, J., Bonneau, D., Mathews, C. D. C., Dattani, R., Edueng, K., He, Y., Holm, R., Madsen, C. M., Müller, T., Muenster, U., Mullertz, Anette , Ojala, K., Rades, Thomas, Sieger, P. & Bergström, C. A. S., Sep 2016, In: Journal of Pharmaceutical Sciences. 105, 9, p. 2864-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo evaluation of lipid-based formulations for oral delivery of apomorphine and its diester prodrugs
Borkar, N. N., Holm, R., Yang, Mingshi, Mullertz, Anette & Mu, Huiling, 9 Sep 2016, In: International Journal of Pharmaceutics. 513, 1-2, p. 211-217 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
Sassene, P. J., Fanø, M., Mu, Huiling, Rades, Thomas, Aquistapace, S., Schmitt, B., Cruz-Hernandez, C., Wooster, T. J. & Mullertz, Anette , 14 Sep 2016, In: Food & Function. 7, 9, p. 3989-3998 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs
Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studying the propensity of compounds to supersaturate: a practical and broadly applicable approach
Palmelund, H., Madsen, C. M., Christensen, J. P., Mullertz, Anette & Rades, Thomas, Oct 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3021-3029 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a μDissolution-Permeation model with in situ drug concentration monitoring
Berthelsen, R., Byrialsen, J. P., Holm, R., Jacobsen, Jette, Abrahamsson, B., Saaby, Lasse, Madelung, P. & Mullertz, Anette , 1 Oct 2016, In: Journal of Drug Delivery Science and Technology. 35, p. 223-233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vivo Precipitation of Poorly Soluble Drugs from Lipid-Based Drug Delivery Systems
Sassene, P. J., Michaelsen, M. H., Mosgaard, M. D., Klitgaard, Mette, Van Den Broek, E., Wasan, K. M., Mu, Huiling, Rades, Thomas & Mullertz, Anette , 3 Oct 2016, In: Molecular Pharmaceutics. 13, 10, p. 3417-3426 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing clinical drug product performance: applying Biopharmaceutics Risk Assessment Roadmap (BioRAM) and the BioRAM Scoring Grid
Dickinson, P. A., Kesisoglou, F., Flanagan, T., Martinez, M. N., Mistry, H. B., Crison, J. R., Polli, J. E., Cruañes, M. T., Serajuddin, A. T. M., Mullertz, Anette , Cook, J. A. & Selen, A., Nov 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3243-3255 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid cellulose nanofiber based foams - Towards facile design of sustained drug delivery systems
Svagan, A. J., Benjamins, J., Al-Ansari, Z., Bar-Shalom, Daniel, Mullertz, Anette , Wågberg, L. & Löbmann, Korbinian, 12 Nov 2016, In: Journal of controlled release : official journal of the Controlled Release Society. 244 , Part A, p. 74–82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Markl, D., Zeitler, J. A., Rasch, C., Michaelsen, M. H., Mullertz, Anette , Rantanen, Jukka, Rades, Thomas & Bøtker, Johan Peter, 2017, In: Pharmaceutical Research. 34, 5, p. 1037–1052 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC
Fjelrad Christfort, J., Christensen, J. P., Madsen, C. M., Nielsen, L. H., Sandau, M., Andersen, K., Mullertz, Anette & Rades, Thomas, 2017, In: Molecular Pharmaceutics. 14, 12, p. 4154-4160Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-microemulsifying drug delivery system and nanoemulsion for enhancing aqueous miscibility of Alpinia galanga oil
Khumpirapang, N., Pikulkaew, S., Mullertz, Anette , Rades, Thomas & Okonogi, S., 2017, In: PLOS ONE. 12, 11, 18 p., e0188848.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro Model Simulating Gastro-Intestinal Digestion in the Pediatric Population (Neonates and Young Infants)
Kamstrup, D., Berthelsen, R., Sassene, P. J., Selen, A. & Mullertz, Anette , Feb 2017, In: A A P S PharmSciTech. 18, 2, p. 317-329 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations
Siqueira, S. D. V. S., Mullertz, Anette , Gräeser, K., Kasten, G., Mu, Huiling & Rades, Thomas, Mar 2017, In: A A P S Journal. 19, 2, p. 587-594 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the intermediate digestion phases of human healthy intestinal contents from distal ileum and caecum at fasted and fed state conditions
Tran, T., Fatouros, D. G., Vertzoni, M., Reppas, C. & Mullertz, Anette , Mar 2017, In: The Journal of pharmacy and pharmacology. 69, 3, p. 265-273 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-Throughput Lipolysis in 96-Well Plates for Rapid Screening of Lipid-Based Drug Delivery Systems
Mosgaard, M. D., Sassene, P. J., Mu, Huiling, Rades, Thomas & Mullertz, Anette , Apr 2017, In: Journal of Pharmaceutical Sciences. 106, 4, p. 1183-1186 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioinspired Layer-by-Layer Microcapsules Based on Cellulose Nanofibers with Switchable Permeability
Paulraj, T., Riazanova, A. V., Yao, K., Andersson, R. L., Mullertz, Anette & Svagan, A. J., 10 Apr 2017, In: Biomacromolecules. 18, 4, p. 1401-1410 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amorphous is not always better—A dissolution study on solid state forms of carbamazepine
Jensen, L. G., Skautrup, F. B., Mullertz, Anette , Abrahamsson, B., Rades, Thomas & Priemel, P. A., 30 Apr 2017, In: International Journal of Pharmaceutics. 522, 1-2, p. 74-79 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery
Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro and in vivo performance of monoacyl phospholipid-based self-emulsifying drug delivery systems
Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Mullertz, Anette & Rades, Thomas, 10 Jun 2017, In: Journal of Controlled Release. 255, p. 45-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug
Larsen, A. T., Holm, R. & Mullertz, Anette , Aug 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 117, p. 308-314 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of oral lipid-based formulations of apomorphine and its diester in a Parkinson's disease rat model
Borkar, N., Andersson, D. R., Yang, Mingshi, Mullertz, Anette , Holm, R. & Mu, Huiling, Sep 2017, In: Journal of Pharmacy and Pharmacology. 69, 9, p. 1110-1115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monoacyl phosphatidylcholine inhibits the formation of lipid multilamellar structures during in vitro lipolysis of self-emulsifying drug delivery systems
Tran, T., Siqueira, S. D. V. S., Amenitsch, H., Rades, Thomas & Mullertz, Anette , 15 Oct 2017, In: European Journal of Pharmaceutical Sciences. 108, p. 62-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide
Svagan, A. J., Mullertz, Anette & Löbmann, Korbinian, Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method
Plum, J., Madsen, C. M., Teleki, A., Bevernage, J., da Costa Mathews, C., Karlsson, E. M., Carlert, S., Holm, R., Müller, T., Matthews, W., Sayers, A., Ojala, K., Tsinsman, K., Lingamaneni, R., Bergström, C. A., Rades, Thomas & Mullertz, Anette , 7 Nov 2017, In: Molecular Pharmaceutics. 14, 12, p. 4161-4169Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studying furosemide solubilization using an in vitro model simulating gastrointestinal digestion and drug solubilization in neonates and young infants
Klitgaard, Mette, Sassene, P. J., Selen, A., Mullertz, Anette & Berthelsen, R., 15 Nov 2017, In: European Journal of Pharmaceutical Sciences. 109, p. 191-199 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From concept to in vivo testing: Microcontainers for oral drug delivery
Mazzoni, C., Tentor, F., Strindberg, S. A., Nielsen, L. H., Keller, S. S., Alstrøm, T. S., Gundlach, C., Mullertz, Anette , Marizza, P. & Boisen, A., 28 Dec 2017, In: Journal of Controlled Release. 268, p. 343-351 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Are phytosomes a superior nanodelivery system for the antioxidant rutin?
Vu, H. T. H., Hook, S. M., Siqueira, S. D., Mullertz, Anette , Rades, Thomas & McDowell, A., 2018, In: International Journal of Pharmaceutics. 548, 1, p. 82-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the hydrodynamics in a miniaturized dissolution apparatus
Johansson, Kristoffer Enøe, Plum, J., Mosleh, M., Madsen, C. M., Rades, Thomas & Mullertz, Anette , 2018, In: Journal of Pharmaceutical Sciences. 107, 4, p. 1095-1103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and characterization of clove oil nanoemulsions and self-microemulsifying drug delivery systems
Kheawfu, K., Pikulkaew, S., Rades, Thomas, Mullertz, Anette & Okonogi, S., 2018, In: Journal of Drug Delivery Science and Technology. 46, p. 330-338 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor® RH40 using experimental design
Tran, T., Rades, Thomas & Mullertz, Anette , 2018, In: Asian Journal of Pharmaceutical Sciences. 13, p. 536-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of composition of simulated intestinal media on the solubility of poorly soluble compounds investigated by design of experiments
Madsen, C. M., Feng, K., Leithead, A., Canfield, N., Jørgensen, S. A., Mullertz, Anette & Rades, Thomas, Jan 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 311-319 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using Potentiometric Free Drug Sensors to Determine the Free Concentration of Ionizable Drugs in Colloidal Systems
Tran, T., Chakraborty, A., Xi, X., Bohets, H., Cornett, Claus, Tsinman, K., Rades, Thomas & Mullertz, Anette , Jan 2018, In: Journal of Pharmaceutical Sciences. 107, 1, p. 103-112Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ability of two in vitro lipolysis models reflecting the human and rat gastro-intestinal conditions to predict the in vivo performance of SNEDDS dosing regimens
Jorgensen, S. D. S., Al Sawaf, M., Graeser, K., Mu, Huiling, Mullertz, Anette & Rades, Thomas, Mar 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 124, p. 116-124Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine
Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrolysed pea proteins mitigate in vitro wheat starch digiestibility
López-Barón , N., Sagnelli, D., Blennow, Andreas, Holse, M., Gao, J., Saaby, Lasse, Mullertz, Anette , Jespersen, Birthe P Møller & Vasanthan, T., Jun 2018, In: Food Hydrocolloids. 79, p. 117-126 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions
Duraipandian, S., Knopp, Matthias Manne, Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)
Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery
Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats
Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers
Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development
Zane, P., Gieschen, H., Kersten, E., Mathias, N., Ollier, C., Johansson, P., Van den Bergh, A., Van Hemelryck, S., Reichel, A., Rotgeri, A., Schäfer, K., Mullertz, Anette & Langguth, P., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 222-231 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymeric Lids for Microcontainers for Oral Protein Delivery
Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology
Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201Research output: Contribution to journal › Letter › Research › peer-review
- Published
In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration
Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, A., Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W. & 2 others, , Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats
Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
- Published
In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery
Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model
Jacobsen, N. M. Y., Caglayan, I., Caglayan, A., Bar-Shalom, Daniel & Mullertz, Anette , 2020, In: International Journal of Pharmaceutics. 591, 7 p., 120022.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adding a Gastric Step to the Intestinal In Vitro Digestion Model Improves the Prediction of Pharmacokinetic Data in Beagle Dogs of Two Lipid-Based Drug Delivery Systems
Klitgaard, Mette, Beilles, S., Sassene, P. J., Berthelsen, R. & Mullertz, Anette , 2020, In: Molecular Pharmaceutics. 17, 9, p. 3214-3222 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of induction methods for supersaturation: Amorphous dissolution versus solvent shift
Plum, J., Bavnhoj, C. G., Eliasen, Jannik Nicklas, Rades, Thomas & Mullertz, Anette , 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 152, p. 35-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of centrifugation speed on the measured equilibrium solubility of poorly water-soluble compounds in viscous solvents
Liu, X., Mullertz, Anette , Bar-Shalom, Daniel & Berthelsen, R., 2020, In: Journal of Drug Delivery Science and Technology. 59, 8 p., 101853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing Stability and Tooth Bleaching Activity of Carbamide Peroxide by Electrospun Nanofibrous Film
Okonogi, S., Kaewpinta, A., Rades, Thomas, Mullertz, Anette , Yang, Mingshi, Khongkhunthian, S. & Chaijareenont, P., 2020, In: Pharmaceuticals. 13, 11, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating side-by-side diffusion models for studying drug supersaturation in an absorptive environment: a case example of fenofibrate and felodipine
Eliasen, Jannik Nicklas, Berthelsen, R., Slot, A. L. & Mullertz, Anette , 2020, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 371-384Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302503
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
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289
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Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › Research › peer-review
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