Lene Jørgensen
Associate Professor
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Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues
Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The challenges in and importance of analysing protein structure and physical stability in complex formulations
Jørgensen, Lene, Jensen, M. G., Roest, N., Pinholt, C. & van de Weert, Marco, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 347-353 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Probing structural changes of proteins incorporated into water-in-oil emulsions
Jørgensen, Lene, van de Weert, Marco, Vermehren, C., Bjerregaard, S. & Frøkjær, Sven, Jul 2004, In: Journal of Pharmaceutical Sciences. 93, 7, p. 1847-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients
Jørgensen, Lene, Hostrup, S., Møller, E. H. & Grohganz, Holger, 2009, In: Expert Opinion on Drug Delivery. 6, 11, p. 1219-1230Research output: Contribution to journal › Review › Research
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Adsorption of insulin with varying self-association profiles to a solid Teflon surface-Influence on protein structures, fibrillation tendency and thermal stability
Jørgensen, Lene, Bennedsen, P., Hoffmann, S. V., Pinholt, C., Krogh, R. L., Jensen, M. G., Hostrup, S. & Burkinksky, J. T., 2011, In: European Journal of Pharmaceutical Sciences. 42, 5, p. 509-516Research output: Contribution to journal › Journal article › Research › peer-review
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Issues in development of biodrug delivery systems
Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug delivery systems: fundamentals, applications and clinical development. Morishita, M. & Park, K. (eds.). New York: Informa Healthcare, p. 13-25Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Biotechnology-based pharmaceuticals
Jørgensen, Lene, Nielsen, Hanne Mørck & Frøkjær, Sven, 2009, Modern pharmaceutics: applications and advances. Florence, A. T. & Siepmann, J. (eds.). 5 ed. New York: Informa Healthcare, Vol. 2. p. 259-293 (Drugs and the Pharmaceutical Sciences, Vol. 188).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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In vitro release of insulin aspart incorporated into water-in-oil emulsions
Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Drug Delivery Science and Technology. 14, 6, p. 455-459Research output: Contribution to journal › Journal article › Research › peer-review
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Secondary structure alteration in insulin and growth hormone water-in-oil emulsions
Jørgensen, Lene, Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2003, In: Internation Journal of Pharmaceutics. 254, 1, p. 7-10Research output: Contribution to journal › Journal article › Research › peer-review
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Micropipette manipulation a technique to evaluate the stability of water-in-oil emulsions containing proteins
Jørgensen, Lene, Kim, D. H., Vermehren, Charlotte, Bjerregaard, S. & Frøkjær, Sven, 2004, In: Journal of Pharmaceutical Sciences. 93, 12, p. 2994-3003Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid based drug delivery systems for proteins: Physical stability of proteins at the oil-water interface
Jørgensen, Lene, 2009, VDM Verlag Dr. Müller Aktiengesellschaft & C o. KG.Research output: Book/Report › Book › Research › peer-review
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Issues in Development of Biodrug Delivery Systems
Jørgensen, Lene, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development. Morishita, M. & Park, K. (eds.). 1 ed. Informa Healthcare, p. 13-25Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines
Jørgensen, Lene & Nielsen, Hanne Mørck, 2009, Wiley. 413 p.Research output: Book/Report › Book › Research › peer-review
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Analysis of protein physical stability in lipid based delivery systems: the challenges of lipid drug delivery systems
Jørgensen, Lene, Martins, S. & van de Weert, Marco, 2009, In: Journal of Biomedical Nanotechnology. 5, 4, p. 401-408Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF)
Jørgensen, Lene, Krøyer Wood, G., Rosenkrands, I., Petersen, C. & Christensen, D., 2009, In: Journal of Liposome Research. 19, 2, p. 99-104Research output: Contribution to journal › Journal article › Research › peer-review
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Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces
Kapp, S. J., Larsson, I., van de Weert, Marco, Cardenas Gomez, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 2, p. 593-601 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Erratum: Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601
Kapp, S. J., Larsson, I., van de Weert, Marco, Ćardenas, M. & Jørgensen, Lene, 2015, In: Journal of Pharmaceutical Sciences. 104, 10, p. 3587 1 p.Research output: Contribution to journal › Comment/debate › Research
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Calcipotriol delivery into the skin with PEGylated liposomes
Knudsen, N. Ø., Rønholt, Stine, Salte, R. D., Jørgensen, Lene, Thormann, T., Basse, L. H., Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 3, p. 532-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor
Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: International Journal of Pharmaceutics. 428, 1-2, p. 171-177Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity
Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485Research output: Contribution to journal › Journal article › Research › peer-review
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Penetration of gel and liquid state liposomes into barrier-impaired skin
Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In: Journal of Pharmacy and Pharmacology. p. 793Research output: Contribution to journal › Conference article › Research › peer-review
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Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity
Lobbens, E. S. B., Vissing, K. J., Jørgensen, Lene, van de Weert, Marco & Jäger, A. K., 22 Mar 2017, In: Journal of Ethnopharmacology. 200, p. 66-73 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation
Lobbens, E. S., Breydo, L., Pedersen, T. S., Vestergaard, Bente, Jäger, A. K., Jørgensen, Lene, Uversky, V. & van de Weert, Marco, 21 Jun 2016, In: B B A - Proteins and Proteomics. 1864, 9, p. 1160-1169 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin
Lobbens, E. S., Foderà, Vito, Nyberg, N., Andersen, K., Jäger, A. K., Jørgensen, Lene & van de Weert, Marco, 16 Feb 2016, In: PloS one. 11, 2, p. 1-16 16 p., e0149148.Research output: Contribution to journal › Journal article › Research › peer-review
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Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299770
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Proteiner i lægemidler - de sætter sig alle de forkerte steder
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Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
Research output: Contribution to journal › Journal article › Research › peer-review
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