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  1. Published

    Synthesis of the thiazole-thiazoline fragment of largazole analogues

    Diness, Frederik, Nielsen, D. S. & Fairlie, D. P., 2 Dec 2011, In: Journal of Organic Chemistry. 76, 23, p. 9845-9851

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

    Pinto, A., Conti, P., Grazioso, G., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte & De Micheli, C., 1 Feb 2011, In: European Journal of Medicinal Chemistry. 46, 2, p. 787-793

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Synthesis of new GABA uptake inhibitors

    Jørgensen, L., 2011, København: Det Farmaceutiske Fakultet. 157 p.

    Research output: Book/Report › Ph.D. thesis › Research

  4. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

    Leke, R., Bak, Lasse Kristoffer, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Schousboe, Arne & Waagepetersen, Helle S., 1 Jun 2011, In: Journal of Neurochemistry. 117, 5, p. 824-32 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Synthesis of imidazole-4(5)-acetic acid analogues: for characterizing the ionotropic GABA receptors

    Madsen, C., 2010, København: Det Farmaceutiske Fakultet. 186 p.

    Research output: Book/Report › Ph.D. thesis › Research

  6. Published

    Synthesis of enantiopure 3-substituted morpholines

    Bornholdt, J., Felding, J. & Kristensen, Jesper Langgaard, 2010, In: Journal of Organic Chemistry. 75, 21, p. 7454-7457

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Synthesis of conformationally constrained glutamic acid homologues and investigation of their pharmacological profiles

    Conti, P., Pinto, A., Tamborini, L., Grazioso, G., De Sarro, G., Bräuner, Hans, Szabo, G., Hársing, L. G. & De Micheli, C., 2007, In: ChemMedChem. 2, 11, p. 1639-1647 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Synthesis of bicyclic acidic amino acids conformationally restricted mimetics of Glu or Asp & work towards the enantioselective total synthesis of cardinalin 3

    Sejberg, J. J. P., 2009, København: Det Farmaceutiske Fakultet. 169 p.

    Research output: Book/Report › Ph.D. thesis › Research

  9. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In: Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In: Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid

    Jørgensen, Charlotte Grube, Clausen, Rasmus Prætorius, Hansen, K. B., Bräuner, Hans, Nielsen, Birgitte, Metzler, B., Kehler, J., Krogsgaard-Larsen, Povl & Madsen, Ulf, 2007, In: Organic & Biomolecular Chemistry. 5, 3, p. 463-471

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid

    Conti, P., Caligiuri, A., Pinto, A., Roda, G., Tamborini, L., Nielsen, Birgitte, Madsen, Ulf, Frydenvang, Karla Andrea, Colombo, A. & De Micheli, C., 2007, In: European Journal of Medicinal Chemistry. 42, 8, p. 1059-1068

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Synthesis and pharmacological characterization at glutamate receptors of erythro- and threo-tricholomic acid and homologues thereof

    Conti, P., De Amici, M., Roda, G., Pinto, A., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte, Bräuner, Hans & De Micheli, C., 2007, In: Tetrahedron. 63, 10, p. 2249-2256

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Synthesis and characterization of an epimer of tacrolimus, an immunosuppressive drug

    Skytte, D. M., Frydenvang, Karla Andrea, Hansen, L., Nielsen, P. G. & Jaroszewski, J. W., 18 Feb 2010, In: Journal of Natural Products. 73, 4, p. 776-779

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives

    Armishaw, C., Jensen, Anders A., Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, Peptides for youth: The proceedings of the 20th American peptide symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). Springer, Vol. 611. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  16. Published

    Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

    Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 17, p. 3087-3091

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Synthesis and application of a new fluorous-tagged ammonia equivalent

    Nielsen, S. D., Smith, G., Begtrup, M. & Kristensen, Jesper Langgaard, 2010, In: Chemistry: A European Journal. 16, 15, p. 4557-4566

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones

    Christensen, M. K., Erichsen, K. D., Trojel-Hansen, C., Tjørnelund, J., Nielsen, S. J., Frydenvang, Karla Andrea, Johansen, Tommy Nørskov, Nielsen, Birgitte, Sehested, M., Jensen, P. B., Ikaunieks, M., Zaichenko, A., Loza, E., Kalvinsh, I. & Björkling, Fredrik, 14 Oct 2010, In: Journal of Medicinal Chemistry. 53, 19, p. 7140-7145 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In: Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Sustaining delivery of the first publicly reimbursed cognitive service in Denmark: a cross-case analysis

    Kaae, Susanne, Søndergaard, B., Nørgaard, Lotte Stig & Traulsen, Janine Marie, 2010, In: International Journal of Pharmacy Practice. 18, 1, p. 21-27

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Suspected adverse drug reactions in children following immunization: retrospective analysis of spontaneous reports over a decade

    Aagaard, L., Hansen, E. W. & Hansen, E. H., 2010, In: Drug Safety. 33, 10, p. 903-904

    Research output: Contribution to journal › Conference abstract in journal › Research

  22. Published

    Susceptibility of bacteria isolated from pigs to tiamulin and enrofloxacin metabolites

    Lykkeberg, A. K., Halling-Sørensen, B. & Jensen, L. B., 2007, In: Veterinary Microbiology. 121, 1-2, p. 116-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Surveying selenium speciation from soil to cell-forms and transformations

    Gammelgaard, Bente, Jackson, M. I. & Gabel-Jensen, C., 2011, In: Analytical and Bioanalytical Chemistry. 399, p. 1743-1763

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Survey of patient and physician assessment of a compliance reminder device in the treatment of hypertension

    Christensen, A., Christrup, Lona Louring, Fabricius, P. E., Chrostowska, M., Wronka, M., Narkiewicz, K. & Hansen, E. H., 2009, In: Blood Pressure. 18, 5, p. 280-285

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Supportive care aspects in cancer 2. Treatment of emesis, neutropenia and alopecia

    Honoré, P. G. H. & Honoré, E., 2007, In: European Journal of Oncology Pharmacy. 1, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Supportive care: alleviating fatigue and pain

    Honoré, P. G. H. & Honoré, E., 2007, In: European Journal of Oncology Pharmacy. 1, 1, p. 28-29

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Supportive care: nutrition problems, alopecia and mucositis

    Honoré, P. G. H. & Honoré, E., 2008, In: European Journal of Oncology Pharmacy. 2, p. 26-27

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Superparamagnetic bead interactions with functionalized surfaces characterized by an immunomicroarray

    Skottrup, P. D., Hansen, M. F., Moresco, J. L., Deryabina, M., Svendsen, W. E., Jakobsen, M. H. & Dufva, M., 2010, In: Acta Biomaterialia. 6, 10, p. 3936-3946 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Sulfoxide, sulfur, and nitrogen oxidation and dealkylation by cytochrome P450

    Rydberg, P. Å. A., Ryde, U. & Olsen, L., 2008, In: Journal of Chemical Theory and Computation. 4, 8, p. 1369-1377

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

    Erreger, K., Geballe, M. T., Kristensen, Anders Skov, Chen, P. E., Hansen, K. B., Lee, C. J., Yuan, H., Le, P., Lyuboslavsky, P. N., Micale, N., Jørgensen, L., Clausen, Rasmus Prætorius, Wyllie, D. J. A., Snyder, J. P. & Traynelis, S. F., 2007, In: Molecular Pharmacology. 72, 4, p. 907-920

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Subunit vaccines of the future: the need for safe, customized and optimized particulated delivery systems

    Foged, Camilla, 2011, In: Therapeutic Delivery. 2, 8, p. 1057-1077

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Subtype-specific suppression of Shiga toxin 2 released from Escherichia coli upon exposure to protein synthesis inhibitors

    Pedersen, M. G., Hansen, C., Riise, E., Persson, S. & Olsen, K. E. P., 2008, In: Journal of Clinical Microbiology. 46, 9, p. 2987-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Subtype selective kainic acid receptor agonists: discovery and approaches to rational design

    Bunch, Lennart & Krogsgaard-Larsen, Povl, 2009, In: Medicinal Research Reviews. 29, 1, p. 3-28

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Study on the binding of Thioflavin T to ß-sheet-rich and non-ß-sheet cavities

    Jensen, M. G., Olsen, L., van de Weert, Marco, Flink, J. M., Frøkjær, Sven & Jørgensen, Flemming Steen, 2007, In: Journal of Structural Biology. 158, 3, p. 358-369

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme a thioester intermediate in rats

    Olsen, J., Li, C., Skonberg, C., Bjørnsdottir, I., Sidenius, U., Benet, L. Z. & Hansen, S. H., 2007, In: Drug Metabolism and Disposition. 35, 5, p. 758-764

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Studies of monoamine transporters: Phosphorylation of the serotonin transporter and interactions of antidepressants with the serotonin and norepinephrine transporters

    Sørensen, L., May 2011, København: Det Farmaceutiske Fakultet. 174 p.

    Research output: Book/Report › Ph.D. thesis › Research

  38. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, P., Kastrup, Jette Sandholm Jensen, Helin, K., Olsen, L. & Gajhede, Michael, Jun 2012, In: F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign

    Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15

    Research output: Contribution to journal › Journal article › Communication

  40. Published

    Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

    Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains

    Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Structures and processes in spontaneous ADR reporting systems: a comparative study of Australia and Denmark

    Aagaard, L., Stenver, D. I. & Hansen, E. H., 2008, In: Pharmacy World and Science. 30, 5, p. 563-570

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+-Transport ATPase (SPCA1a)

    Jialin, C., de Raeymaecker, J., Hovgaard, J. B., Smaardijk, S., Vandecaetsbeek, I., Wuytack, F., Møller, J. V., Eggermont, J., de Meyer, M., Christensen, Søren Brøgger & Vangheluwe, P., 2017, In: Journal of Biological Chemistry. 292, 17, p. 6938-6951 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Structure-function studies of proteins by unnatural amino acid mutagenesis

    Rannes, J. G., 2008, København: Det Farmaceutiske Fakultet. 136 p.

    Research output: Book/Report › Ph.D. thesis › Research

  45. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In: ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101)

    Erichsen, M. N., Huynh, Tri Hien Viet, Abrahamsen, B., Bastlund, J. F., Bundgaard, C., Monrad, O., Bekker-Jensen, A., Nielsen, C. W., Frydenvang, Karla Andrea, Jensen, Anders A. & Bunch, Lennart, 2010, In: Journal of Medicinal Chemistry. 53, 19, p. 7180–7191

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors

    Bräuner, Hans, Wellendorph, Petrine & Jensen, Anders A., 2007, In: Current Drug Targets. 8, 1, p. 169-184

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Structure of the first PDZ domain of human PSD-93

    Fiorentini, M., Nielsen, A. K., Kristensen, O., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2009, In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 65, 12, p. 1254-1257

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

    Kristensen, O., Ross, B. & Gajhede, Michael, 2008, In: Journal of Molecular Biology. 375, 5, p. 1469-1476

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Structure of a fatty acid-binding protein from Bacillus subtilis determined by sulfur-SAD phasing using in-house chromium radiation

    Nan, J., Zhou, Y., Yang, C., Brostromer, E., Kristensen, O. & Su, X., 2009, In: Acta Crystallographica. Section D: Biological Crystallography. 65, 5, p. 440-448

    Research output: Contribution to journal › Journal article › Research › peer-review

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