Research areas

  1. Published

    Surveying selenium speciation from soil to cell-forms and transformations

    Gammelgaard, Bente, Jackson, M. I. & Gabel-Jensen, C., 2011, In: Analytical and Bioanalytical Chemistry. 399, p. 1743-1763

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Synthesis of new GABA uptake inhibitors

    Jørgensen, L., 2011, København: Det Farmaceutiske Fakultet. 157 p.

    Research output: Book/ReportPh.D. thesisResearch

  3. Published

    Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

    Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In: International Journal of Pharmaceutics. 416, p. 478-485

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The cysteine protease RgpB as a biomarker for the periodonto-pathogen Porphyromonas gingivalis: Nanobody selection and assay development

    Skottrup, P. D., Leonard, P., Kaczmarek, J., Veillard, F., Johannes Enghild, J., O'Kennedy, R., Sroka, A., Clausen, Rasmus Prætorius, Potempa, J. & Riise, E. S., 2011.

    Research output: Contribution to conferencePosterResearch

  5. Published

    The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations ?

    Pinholt, C., Hartvig, R. A., Medlicott, N. J. & Jørgensen, Lene, 2011, In: Expert Opinion on Drug Delivery. 8, 7, p. 949-964

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The influence of size, structure and hydrophilicity of model surfactants on the adsorption of lysozyme to oil-water interface-Interacial shear measurements

    Baldursdóttir, S. G. & Jørgensen, Lene, 2011, In: Colloids and Surfaces B: Biointerfaces. 87, p. 96-102

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres

    Thakral, N. K., Ray, A. R., Bar-Shalom, Daniel, Eriksson, A. H. & Majumdar, D. K., 2011, In: International Journal of Nanomedicine. 6, p. 1057-1068

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The relationship between leadership style and provision of the first Danish publicly reimbursed cognitive pharmaceutical service - A qualitative multicase study

    Kaae, Susanne, Søndergaard, B., Nørgaard, Lotte Stig & Traulsen, Janine Marie, 2011, In: Research in Social and Administrative Pharmacy. 7, 2, p. 113-121

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The role of calcium in membrane condensations and spontaneous curvature variations in model lipidic systems

    Yaghmur, Anan, Sartori, B. & Rappolt, M., 2011, In: Physical Chemistry Chemical Physics. 13, 8, p. 3115-3125

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The role of conjugation in the gene-individual-population relationships in increasing eco-exergy

    Cho, W., Jørgensen, S. E. & Chon, T., 2011, In: Ecological Modelling. 222, 3, p. 407-418

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The use of Xenopus oocytes in drug screening

    Kvist, T., Hansen, K. B. & Bräuner, Hans, 2011, In: Expert Opinion on Drug Discovery. 6, 2, p. 141-153

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Thermal and acid denaturation of bovine lens a-crystallin

    Rasmussen, T., van de Weert, Marco, Jiskoot, W. & Kasimova, M. R., 2011, In: Proteins - Structure Function and Bioinformatics. 79, 6, p. 1747-1758

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Thermodynamic stability and denaturation kinetics of a benign natural transthyretin mutant identified in a Danish kindred

    Jensen, M. G., Campos, R. I., Fagerberg, C., Rasmussen, A. A., Eriksen, U. H., Powers, E. T. & Hammarström, P., 2011, In: Amyloid: the Journal of Protein Folding Disorders. 18, 2, p. 35-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes

    Jacobsen, J. K., Jensen, B., Skonberg, C., Hansen, S. H. & Badolo, L., 2011, In: European Journal of Pharmaceutical Sciences. 44, 3, p. 427-436

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Toltrazuril and its two main metabolites in the environment - Analytical development

    Olsen, J., Hansen, M., Krogh, K. A., Bak, S. A., Brandt, A. & Björklund, E., 2011.

    Research output: Contribution to conferencePosterResearch

  16. Published

    Toltrazuril and its two main metabolites in the environment: Degradation and algae toxicity

    Havsland, M. C., Hansen, M., Bak, S. A., Björklund, E., Brandt, A. & Krogh, K. A., 2011.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Transformation of structurally diverse steroidal analogues by the fungus Corynespora cassiicola CBS 161.60 results in generation of 8ß-hydroxylated metabolites with evidence in favor of 8ß-hydroxylation through inverted binding in the 9a-hydroxylase

    Hunter, A. C., Rymer, S., Dedi, C., Dodd, H. T., Nwozor, Q. C. & Moghimi, S. M., 2011, In: BBA General Subjects. 1811, 12, p. 1054-1061

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Transport af lægemiddelstoffer gennem vævsbarrier

    Nielsen, C. U. & Larsen, Birger Brodin, 2011, Bioteknologi - en temabog. Gasbjerg, P. K., Jensen, G. S. & Sørensen, A. B. (eds.). Århus: Systime, p. 145-157 12 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  19. Published

    Uklare retningslinjer om D-vitamintilskud til etniske minoriteter

    Mygind, A., Traulsen, Janine Marie & Nørgaard, Lotte Stig, 2011, In: Lægemiddelforskning. 2011, p. 33-35 3 p.

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    Versatile flow-injection amperometric ion detector based on an interface between two immiscible electrolyte solutions: numerical and experimental characterization

    Deryabina, M., Hansen, S. H. & Jensen, H., 2011, In: Analytical Chemistry. 83, 19, p. 7388-7393

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    X-ray powder diffractormetry in combination with principal component analysis - A tool for monitoring solid state changes

    Kogermann, K., Veski, P., Rantanen, Jukka & Naelapaa, K., 2011, In: European Journal of Pharmaceutical Sciences. 43, p. 278-289

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    sdf2xyz2sdf: How to exploit TINKER power in cheminformatics projects

    Tosco, P. & Balle, T., 2011

    Research output: Non-textual formComputer programmeResearch

  23. Published

    Effects of bile on the oral absorption of poorly water-soluble drugs in rats

    Tønsberg, H., Jan 2011, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 83 p.

    Research output: Book/ReportPh.D. thesisResearch

  24. Published

    On-chip electro membrane extraction with online ultaviolet and mass spectrometric detection

    Petersen, Nickolaj J., Foss, S. T., Jensen, H., Hansen, S. H., Skonberg, C., Snakenborg, D., Kutter, J. P. & Pedersen-Bjergaard, Stig, Jan 2011, In: Analytical Chemistry. 83, 1, p. 44-51

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators

    Pøhlsgaard, J., Frydenvang, Karla Andrea, Madsen, Ulf & Kastrup, Jette Sandholm Jensen, 1 Jan 2011, In: Neuropharmacology. 60, 1, p. 135-150

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Potentiating action of propofol at GABAA receptors of retinal bipolar cells

    Yue, L., Xie, A., Bruzik, K. S., Frølund, Bente, Qian, H. & Pepperberg, D. R., 1 Jan 2011, In: Investigative Ophthalmology & Visual Science. 52, 5, p. 2497-2509

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Purification, crystallization and preliminary X-ray diffraction of the G3BP1 NTF2-like domain

    Vognsen, T., Möller, I. R. & Kristensen, O., 1 Jan 2011, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 67, Pt 1, p. 48-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors

    Nilsson, J., Gidlöf, R., Nielsen, E. Ø., Liljefors, T., Nielsen, M. P. C. & Sterner, O., 1 Jan 2011, In: Bioorganic & Medicinal Chemistry. 19, 1, p. 111-121

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

    Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Intestinal drug delivery via hPEPT1 : in vitro and in silico evaluation of the realtionship between substrate, binding and translocation

    Omkvist, D. H., Feb 2011, Det Farmaceutiske Fakultet. 51 p.

    Research output: Book/ReportPh.D. thesisResearch

  31. Published

    Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)

    Saaby, Lasse, Jäger, A. K., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Feb 2011, In: Phytotherapy Research. 25, 2, p. 195-201

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Synthesis of new isoxazoline-based acidic amino acids and investigation of their affinity and selectivity profile at ionotropic glutamate receptors

    Pinto, A., Conti, P., Grazioso, G., Tamborini, L., Madsen, Ulf, Nielsen, Birgitte & De Micheli, C., 1 Feb 2011, In: European Journal of Medicinal Chemistry. 46, 2, p. 787-793

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97

    Chi, C. N., Bach, Anders, Engström, Å., Strømgaard, Kristian, Lundström, P., Ferguson, N. & Jemth, P., 4 Feb 2011, In: Journal of Biological Chemistry. 286, 5, p. 3597-3606

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics

    Bach, Anders & Strømgaard, Kristian, 8 Feb 2011, In: Synthesis. 2011, 5, p. 807-815

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Flavonoids and the CNS

    Jäger, A. K. & Saaby, Lasse, 10 Feb 2011, In: Molecules. 16, 2, p. 1471-1485

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Functional and structural studies of neuronal D-serine transporter Asc1

    Wang, X., 10 Feb 2011, København: Det Farmaceutiske Fakultet. 148 p.

    Research output: Book/ReportPh.D. thesisResearch

  37. Published

    Medicinal chemistry of competitive kainate receptor antagonists

    Larsen, A. M. & Bunch, Lennart, 16 Feb 2011, In: ACS Chemical Neuroscience. 2, 2, p. 60-74

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp

    Runager, K., Basaiawmoit, R. V., Deva, T., Andreasen, M., Valnickova, Z., Sørensen, C. S., Karring, H., Thøgersen, I. B., Christiansen, G., Underhaug, J., Kristensen, T., Nielsen, N. C., Klintworth, G. K., Otzen, D. E. & Enghild, J. J., 18 Feb 2011, In: The Journal of Biological Chemistry. 286, 7, p. 4951-4958

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    G protein- and agonist-bound serotonin 5-HT2A receptor model activated by steered molecular dynamics simulations

    Ísberg, V., Balle, T., Sander, T., Jørgensen, Flemming Steen & Gloriam, David E., 28 Feb 2011, In: Journal of Chemical Information and Modeling. 51, 2, p. 315-325

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    European new safe and innovative medicines initiatives: history and progress (through December 2009)

    Bjerrum, Ole Jannik & H. Linden, H., Mar 2011, Translational medicine and drug discovery. Cambridge: Cambridge University Press, p. 265-288 23 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  41. Published

    Metabolic profiling of Rhodiola rosea rhizomes by 1H NMR spectroscopy

    Ioset, K. N., Nyberg, N. T., Van Diermen, D., Malnoe, P., Hostettmann, K., Shikov, A. N. & Jaroszewski, J. W., Mar 2011, In: Phytochemical Analysis. 22, 2, p. 158-165

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity

    Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In: Biochemical Systematics and Ecology. 39, 2, p. 153-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glutamate receptor agonists: stereochemical aspects

    Vogensen, S. B., Greenwood, J. R., Bunch, Lennart & Clausen, Rasmus Prætorius, Apr 2011, In: Current Topics in Medicinal Chemistry. 11, 7, p. 887-906

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Discovery of benzamide analogues as a novel class of 5-HT3 receptor agonists

    Jørgensen, Charlotte Grube, Frølund, Bente, Kehler, J. & Jensen, Anders A., 4 Apr 2011, In: ChemMedChem. 6, 4, p. 725-736

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    ZP2307, a novel cyclic PTH(1-17) analog, reversed established osteopenia in adult ovariectomized rats

    Vääräniemi, J., Morko, J., Peng, Z., Rissanen, J. P., Suominen, M. I., Fagerlund, K. M., Suutari, T. A., Boonen, H. C. M., Neerup, T. S., Bak, H. H. & Halleen, J. M., 7 Apr 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  47. Published

    Electrophilic organic selenium reagents: protonated seleninic acids as precursors for unsymmetrical aromatic selenides

    Stuhr-Hansen, N., Sølling, Theis Ivan & Henriksen, L., 8 Apr 2011, In: Tetrahedron. 67, 14, p. 2633-2643

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain)

    López, V., Jäger, A. K., Akerreta, S., Cavero, R. Y. & Calvo, M. I., 12 Apr 2011, In: Journal of Ethnopharmacology. 134, 3, p. 1014-1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In: European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    1,2,3-triazoles in peptidomimetic chemistry

    Pedersen, D. S. & Abell, A., May 2011, In: European Journal of Organic Chemistry. 2011, 13, p. 2399-2411

    Research output: Contribution to journalReviewResearchpeer-review