Thomas Rades
Professor
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
- Published
Difficulties of Subsurface Liquid Front Tracking in Porous Media with Terahertz Pulsed Imaging
Al-Sharabi, M., Mudley, T., Markl, D., Bawuah, P., Karttunen, A. P., Ridgway, C. J., Gane, P. A. C., Ketolainen, J., Peiponen, K. E., Rades, Thomas & Zeitler, J. A., 2019, 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves. IEEE, 8874143. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, Vol. 2019-September).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects
Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114Research output: Contribution to journal › Review › Research › peer-review
- Published
Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology
Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends
Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions
Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy
Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency Raman Spectroscopic Study on Compression-Induced Destabilization in Melt-Quenched Amorphous Celecoxib
Bērziņš, Kārlis, Fraser-Miller, S. J., Rades, Thomas & Gordon, K. C., 2019, In: Molecular Pharmaceutics. 16, 8, p. 3678-3686 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystalline adduct of moxifloxacin with trans-cinnamic acid to reduce the aqueous solubility and dissolution rate for improved residence time in the lungs
Eedara, B. B., Tucker, I. G., Zujovic, Z. D., Rades, Thomas, Price, J. R. & Das, S. C., 2019, In: European Journal of Pharmaceutical Sciences. 136, 104961.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanochemical activated dry amorphisation by milling equilibrium between ap mesoporous silica
Hoefer, H. H., Monsuur, F. H., Pauly, T., Choudhari, Y., Löbmann, Korbinian & Rades, Thomas, 2019, Patent No. US20190350855A1Research output: Patent
- Published
Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension
Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201Research output: Contribution to journal › Letter › Research › peer-review
- Published
Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation
Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.Research output: Contribution to journal › Journal article › Communication
- Published
Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-former selection for co-amorphous drug-amino acid formulations
Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of Stable Co-Amorphous Drug-Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures
Kissi, E. O., Khorami, Keyoomars & Rades, Thomas, 2019, In: Pharmaceutics. 11, 11 p., 628.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilizing nanoparticles for improving anti-biofilm effects of azithromycin: A head-to-head comparison of modified hyaluronic acid nanogels and coated poly (lactic-co-glycolic acid) nanoparticles
Kłodzińska, S. N., Wan, F., Jumaa, H., Sternberg, C., Rades, Thomas & Nielsen, Hanne Mørck, 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 595-606 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5
Kłodzińska, S. N., Pletzer, D., Rahanjam, N., Rades, Thomas, Hancock, R. E. W. & Nielsen, Hanne Mørck, 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 20, 102022.Research output: Contribution to journal › Journal article › Research › peer-review
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Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis
Lababidi, N., Kissi, E. O., Elgaher, W. A. M., Sigal, V., Haupenthal, J., Schwarz, B. C., Hirsch, A. K. H., Rades, Thomas & Schneider, M., 28 Nov 2019, In: Journal of Controlled Release. 314, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes
Li, T., Nowell, C. J., Cipolla, D., Rades, Thomas & Boyd, B. J., Apr 2019, In: Molecular Pharmaceutics. 16, 4, p. 1775-1781Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio
Li, T., Clulow, A. J., Nowell, C. J., Hawley, A., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Journal of Colloid and Interface Science. 555, p. 361-372 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid State Characterization of Ciprofloxacin Liposome Nanocrystals
Li, T., Mudie, S., Cipolla, D., Rades, Thomas & Boyd, B. J., 2019, In: Molecular Pharmaceutics. 16, 1, p. 184-194 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhalable co-amorphous budesonide-arginine dry powders prepared by spray drying
Lu, W., Rades, Thomas, Rantanen, Jukka & Yang, Mingshi, 30 Jun 2019, In: International Journal of Pharmaceutics. 565, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats
Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A co-amorphous form of a substance and a protein
Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1Research output: Patent
- Published
Imaging of dehydration in particulate matter using Raman line-focus microscopy
Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spectroscopic Evidence of Tertiary Structural Differences Between Insulin Molecules in Fibrils
Schack, M. M., Dahl, K., Rades, Thomas, Groenning, M. & Carpenter, J. F., 2019, In: Journal of Pharmaceutical Sciences. 108, 9, p. 2871-2879Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization of Infrared Microscopy to Assess Secondary Structure of Insulin Molecules Within Individual Subvisible Particles in Aqueous Formulations
Schack, M. M., Moller, E. H., Friderichsen, A. V., Carpenter, J. F., Rades, Thomas & Groenning, M., 2019, In: Journal of Pharmaceutical Sciences. 108, 3, p. 1117-1129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-aqueous topical compositions comprising a halogenated salicylanilide
Sommer, M., Li, P., Frandsen, C. H., Nielsen, Hanne Mørck, Priemel, P. A. & Rades, Thomas, 2019, Patent No. US20190151231A1Research output: Patent
- Published
The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering
Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures
Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct Measurement of Amorphous Solubility
Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of two different PEGylation strategies for the liposomal adjuvant CAF09: Towards induction of CTL responses upon subcutaneous vaccine administration
Tandrup Schmidt, S., Line Olsen, C., Franzyk, Henrik, Wørzner, K., Smith Korsholm, K., Rades, Thomas, Andersen, P., Foged, Camilla & Christensen, D., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 140, p. 29-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptides as co-formers in co-amorphous systems
Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transformations between Co-Amorphous and Co-Crystal Systems and Their Influence on the Formation and Physical Stability of Co-Amorphous Systems
Wu, W., Wang, Y., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1294-1304 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the effects of spray drying parameters for producing cubosome powder precursors
von Halling Laier, C., Sonne Alstrøm, T., Travers Bargholz, M., Bjerg Sjøltov, P., Rades, Thomas, Boisen, A. & Nielsen, L. H., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 135, p. 44-48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microcontainers for protection of oral vaccines, in vitro and in vivo evaluation
von Halling Laier, C., Gibson, B., Moreno, J. A. S., Rades, Thomas, Hook, S., Nielsen, L. H. & Boisen, A., 2019, In: Journal of Controlled Release. 294, p. 91-101 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38132533
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Analysis of 3D Prints by X-ray Computed Microtomography and Terahertz Pulsed Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
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320
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Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates
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