Korbinian Löbmann
Guest Researcher
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
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Preparation and characterization of spray-dried co-amorphous drug-amino acid salts
Jensen, K. B. T., Blaabjerg, L. I., Lenz, E., Bohr, A., Grohganz, Holger, Kleinebudde, P., Rades, Thomas & Löbmann, Korbinian, May 2016, In: The Journal of pharmacy and pharmacology. 68, 5, p. 615–624 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stabilizing Mechanisms of β-Lactoglobulin in Amorphous Solid Dispersions of Indomethacin
Kabedev, A., Zhuo, Xuezhi, Leng, D., Foderà, Vito, Zhao, M., Larsson, P., Bergström, C. A. S. & Löbmann, Korbinian, 2022, In: Molecular Pharmaceutics. 19, 11, p. 3922–3933Research output: Contribution to journal › Journal article › Research › peer-review
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Process Optimization and Upscaling of Spray-Dried Drug-Amino acid Co-Amorphous Formulations
Kasten, G., Duarte, Í., Paisana, M., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 9 Jan 2019, In: Pharmaceutics. 11, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine
Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a screening method for co-amorphous formulations of drugs and amino acids
Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine
Kasten, G., Nouri, K., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Nov 2017, In: International Journal of Pharmaceutics. 533, 1, p. 138-144 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-former selection for co-amorphous drug-amino acid formulations
Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of Glass Transition Temperatures in Coamorphous Drug-Amino Acid Formulations
Kissi, E. O., Kasten, G., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 4 Sep 2018, In: Molecular Pharmaceutics. 15, 9, p. 4247–4256Research output: Contribution to journal › Journal article › Research › peer-review
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Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs
Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility
Knopp, Matthias Manne, Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, Korbinian, Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, Thomas, 8 Sep 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances and potential applications of modulated differential scanning calorimetry (mDSC) in drug development
Knopp, Matthias Manne, Löbmann, Korbinian, Elder, D. P., Rades, Thomas & Holm, R., 1 May 2016, In: European Journal of Pharmaceutical Sciences. 87, p. 164-173 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques
Knopp, Matthias Manne, Olesen, N. E., Holm, P., Löbmann, Korbinian, Holm, R., Langguth, P. & Rades, Thomas, Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Emerging trends in the stabilization of amorphous drugs
Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Supersaturating drug delivery systems: The potential of co-amorphous drug formulations
Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Priemel, P., Strachan, C. J. & Rades, Thomas, 30 Oct 2017, In: International Journal of Pharmaceutics. 532, 1, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using dextran of different molecular weights to achieve faster freeze-drying and improved storage stability of lactate dehydrogenase
Larsen, B. S., Skytte, J., Svagan, A. J., Meng-Lund, H., Grohganz, Holger & Löbmann, Korbinian, 2019, In: Pharmaceutical Development and Technology. 24, 3, p. 323-328Research output: Contribution to journal › Journal article › Research › peer-review
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Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy
Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.Research output: Contribution to journal › Journal article › Research › peer-review
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Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin-arginine
Lenz, E., Jensen, K. B. T., Blaabjerg, L. I., Knop, K., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Kleinebudde, P., Oct 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 96, p. 44–52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hot Melt Extrusion and Spray Drying of Co-amorphous Indomethacin-Arginine With Polymers
Lenz, E., Löbmann, Korbinian, Rades, Thomas, Knop, K. & Kleinebudde, P., Jan 2017, In: Journal of Pharmaceutical Sciences. 106, 1, p. 302-312 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-Amorphous Drug Formulations in Numbers: Recent Advances in Co-Amorphous Drug Formulations with Focus on Co-Formability, Molar Ratio, Preparation Methods, Physical Stability, In Vitro and In Vivo Performance, and New Formulation Strategies
Liu, J., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Hempel, N., 2021, In: Pharmaceutics. 13, 3, 43 p., 389.Research output: Contribution to journal › Review › Research
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Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions
Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888Research output: Contribution to journal › Journal article › Research › peer-review
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Special issue on “Formulation strategies and manufacturing technologies to enhance non-invasive drug delivery”
Löbmann, Korbinian, Bohr, A. & Yang, Mingshi, 1 Nov 2018, In: Asian Journal of Pharmaceutical Sciences. 13, 6, p. 505-506 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement
Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stabilized amorphous solid dispersions with small molecule excipients
Löbmann, Korbinian, Jensen, K. B. T., Laitinen, R., Rades, Thomas, Strachan, C. & Grohganz, Holger, 2014, Amorphous Solid Dispersions - Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (eds.). New York: Springer Science+Business Media, p. 613-626 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers
Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17Research output: Contribution to journal › Journal article › Communication
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Co-amorphous drug-delivery systems
Löbmann, Korbinian, 2013Research output: Other contribution › Net publication - Internet publication › Communication
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Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery
Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.Research output: Contribution to journal › Journal article › Research › peer-review
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Cellulose nanofibers as excipient for the delivery of poorly soluble drugs
Löbmann, Korbinian & Svagan, A. J., 23 Sep 2017, In: International Journal of Pharmaceutics. 533, 1, p. 285-297 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of pressure on the intrinsic dissolution rate of amorphous indomethacin
Löbmann, Korbinian, Flouda, K., Qiu, D., Tsolakou, T., Wang, W. & Rades, Thomas, 2014, In: Pharmaceutics. 6, 3, p. 481-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ordnung muss (nicht) sein
Löbmann, Korbinian, Jensen, K. B. T., Grohganz, Holger & Rades, Thomas, 2012, In: Lægemiddelforskning. 2012, p. 34-36Research output: Contribution to journal › Journal article › Communication
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Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids
Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
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A co-amorphous form of a substance and a protein
Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1Research output: Patent
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Whey proteins as stabilizers in amorphous solid dispersions
Mishra, J., Bohr, A., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 1 Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, p. 144-151 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solvent free amorphisation for pediatric formulations (minitablets) using mesoporous silica
Monsuur, F., Choudhari, Y., Reddy, U., McCarthy, W., Sadek, I., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 25 Sep 2016, In: International Journal of Pharmaceutics. 511, 2, p. 1135-1136Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Constraints on CaCO3 precipitation in superabsorbent polymer by aerobic bacteria
Nielsen, S. D., Koren, K., Löbmann, Korbinian, Hinge, M., Scoma, A., Kjeldsen, K. U. & Roy, H., 2020, In: Applied Microbiology and Biotechnology. 104, 1, p. 365-375Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of anaerobic thermophilic endospores in marine sediment by microcalorimetry, and its use in bioprospecting for gas and oil: Quantification of endospores by microcalorimetry
Nielsen, S. D., Volpi, M., Löbmann, Korbinian, Kjeldsen, K. U. & Røy, H., 2017, In: Limnology and Oceanography: Methods. 15, 6, p. 519-530Research output: Contribution to journal › Journal article › Research › peer-review
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Role of polymeric excipients in the stabilization of olanzapine when exposed to aqueous environments
Paisana, M., Wahl, M., Pinto, J., Rades, Thomas (ed.), Grohganz, Holger (ed.) & Löbmann, Korbinian (ed.), 2015, In: Molecules. 20, 12, p. 22634-223282 200649.Research output: Contribution to journal › Journal article › Research › peer-review
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Deliquescence Behavior of Deep Eutectic Solvents
Palmelund, H., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: Applied Sciences. 11, 9 p., 1601.Research output: Contribution to journal › Letter › Research › peer-review
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Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations
Palmelund, H., Eriksen, J. B., Bauer-Brandl, A., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: International Journal of Pharmaceutics: X. 3, 100083.Research output: Contribution to journal › Journal article › Research › peer-review
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Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)
Palmelund, H., Andersson, M. P., Asgreen, Camilla Jantzen, Boyd, B. J., Rantanen, Jukka & Löbmann, Korbinian, 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100034.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of water of crystallization on the ternary phase behavior of a drug and deep eutectic solvent
Palmelund, H., Boyd, B. J., Rantanen, Jukka & Löbmann, Korbinian, 2020, In: Journal of Molecular Liquids. 315, p. 1-7 113727.Research output: Contribution to journal › Journal article › Research › peer-review
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Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., Oct 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 150-160 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40442243
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
Research output: Contribution to journal › Journal article › Research › peer-review
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204
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
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157
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
Research output: Contribution to journal › Journal article › Research › peer-review
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