Korbinian Löbmann

Korbinian Löbmann

Guest Researcher


  1. Published

    A Comparative Study between A Protein Based Amorphous Formulation and Other Dissolution Rate Enhancing Approaches: A Case Study with Rifaximin

    Zhuo, Xuezhi, Margrethe Brekstad Kjellin, M., Schaal, Z., Zhang, T., Löbmann, Korbinian & Leng, D., 2023, In: Pharmaceutics. 15, 1, 10 p., 126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A co-amorphous form of a substance and a protein

    Mishra, J., Bohr, A., Berg, T. H. A., Löbmann, Korbinian, Rades, Thomas, Grohganz, Holger & Water, J. J., 2019, Patent No. US201903078886A1

    Research output: Patent

  3. Published

    A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica

    Hempel, N., Brede, K., Olesen, N. E., Genina, Natalja, Knopp, Matthias Manne & Löbmann, Korbinian, 18 Apr 2018, In: International Journal of Pharmaceutics. 544, 1, p. 153-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Strachan, C. J., Rades, Thomas & Gordon, K. C., 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 80-87 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability

    Laitinen, R., Löbmann, Korbinian, Grohganz, Holger, Strachan, C. & Rades, Thomas, 7 Jul 2014, In: Molecular Pharmaceutics. 11, 7, p. 2381-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement

    Löbmann, Korbinian, Grohganz, Holger, Laitinen, R., Strachan, C. & Rades, Thomas, Nov 2013, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 85, 3 Pt B, p. 873-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions

    Löbmann, Korbinian, Laitinen, R., Strachan, C., Rades, Thomas & Grohganz, Holger, 1 Jan 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, Part B, p. 882-888

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Amorphization within the tablet: Using microwave irradiation to form a glass solution in situ

    Doreth, M., Hussein, M. A., Priemel, P. A., Grohganz, Holger, Holm, R., Lopez de Diego, H., Rades, Thomas & Löbmann, Korbinian, 15 Mar 2017, In: International Journal of Pharmaceutics. 519, 1-2, p. 343-351 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Amorphous drug stabilization using mesoporous materials

    Veloso, D. F. M. C., Knopp, Matthias Manne & Löbmann, Korbinian, 2020, Drug delivery trends. Elsevier, Vol. 3. p. 151-166

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Jensen, K. B. T., Graeser, K., Strachan, C. & Rades, Thomas, 1 Jul 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 403-408 6 p.

    Research output: Contribution to journalReviewResearch

  11. Published

    Amorphous drugs and dosage forms

    Grohganz, Holger, Löbmann, Korbinian, Priemel, P., Tarp Jensen, K., Graeser, K., Strachan, C. & Rades, Thomas, 2013, In: Journal of Drug Delivery Science and Technology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches

    Zhuo, Xuezhi, Foderà, Vito, Larsson, P., Schaal, Z., Bergström, C. A. S., Löbmann, Korbinian & Kabedev, A., 2024, In: European Journal of Pharmaceutical Sciences. 192, 13 p., 106639.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

    Bøtker, Johan Peter, Rantanen, Jukka, Arnfast, L., Doreth, M., Raijada, D. K., Löbmann, Korbinian, Madsen, C. M., Khan, J., Rades, Thomas, Mullertz, Anette , Hawley, A., Thomas, D. & Boyd, B. J., Mar 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Aspartame as a co-former in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Grohganz, Holger & Rades, Thomas, 5 Oct 2018, In: International Journal of Pharmaceutics. 549, 1-2, p. 380-387

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Cellulose Nanopaper and Nanofoam for Patient-Tailored Drug Delivery

    Löbmann, Korbinian, Wohlert, J., Mullertz, Anette , Wågberg, L. & Svagan, A. J., May 2017, In: Advanced Materials Interfaces. 4, 9, 11 p., 1600655.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cellulose nanofibers as excipient for the delivery of poorly soluble drugs

    Löbmann, Korbinian & Svagan, A. J., 23 Sep 2017, In: International Journal of Pharmaceutics. 533, 1, p. 285-297 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs

    Kissi, E. O., Ruggiero, M. T., Hempel, N. J., Song, Z., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Jan 2019, In: Physical Chemistry Chemical Physics. 21, 35, p. 19686-19694 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Characterization of Amorphous and Co-Amorphous Simvastatin Formulations Prepared by Spray Drying

    Craye, G., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., 2015, In: Molecules. 20, 12, p. 21532-48 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published
  21. Published

    Co-amorphous drug-delivery systems

    Löbmann, Korbinian, 2013

    Research output: Other contributionNet publication - Internet publicationCommunication

  22. Published

    Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions

    Löbmann, Korbinian, Strachan, C., Grohganz, Holger, Rades, Thomas, Korhonen, O. & Laitinen, R., 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 1, p. 159-69 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Co-former selection for co-amorphous drug-amino acid formulations

    Kasten, G., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2019, In: International Journal of Pharmaceutics. 557, p. 366-373

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger, Gordon, K. C., Strachan, C. & Rades, Thomas, 2011, In: Molecular Pharmaceutics. 8, 5, p. 1919-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility

    Knopp, Matthias Manne, Tajber, L., Tian, Y., Olesen, N. E., Jones, D. S., Kozyra, A., Löbmann, Korbinian, Paluch, K., Brennan, C. M., Holm, R., Healy, A. M., Andrews, G. P. & Rades, Thomas, 8 Sep 2015, In: Molecular Pharmaceutics. 12, 9, p. 3408-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Comparison of co-former performance in co-amorphous formulations: Single amino acids, amino acid physical mixtures, amino acid salts and dipeptides as co-formers

    Wu, W., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2021, In: European Journal of Pharmaceutical Sciences. 156, 8 p., 105582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Constraints on CaCO3 precipitation in superabsorbent polymer by aerobic bacteria

    Nielsen, S. D., Koren, K., Löbmann, Korbinian, Hinge, M., Scoma, A., Kjeldsen, K. U. & Roy, H., 2020, In: Applied Microbiology and Biotechnology. 104, 1, p. 365-375

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Convection-Induced vs. Microwave Radiation-Induced in situ Drug Amorphization

    Hempel, N., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2020, In: Molecules. 25, 5, 7 p., 1068.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Deliquescence Behavior of Deep Eutectic Solvents

    Palmelund, H., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: Applied Sciences. 11, 9 p., 1601.

    Research output: Contribution to journalLetterResearchpeer-review

  30. Published

    Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy

    Leng, D., Kissi, E. O., Löbmann, Korbinian, Thanki, K., Fattal, E., Rades, Thomas, Foged, Camilla & Yang, Mingshi, 7 Mar 2019, In: AAPS PharmSciTech. 20, 3, 137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Development of a multiparticulate drug delivery system for in situ amorphisation

    Holm, T. P., Kokott, M., Knopp, Matthias Manne, Boyd, Ben, Berthelsen, R., Quodbach, J. & Löbmann, Korbinian, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 170-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Development of a screening method for co-amorphous formulations of drugs and amino acids

    Kasten, G., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, Dec 2016, In: European Journal of Pharmaceutical Sciences. 95, p. 28-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Dipeptides as co-formers in co-amorphous systems

    Wu, W., Löbmann, Korbinian, Schnitzkewitz, J., Knuhtsen, A., Pedersen, D. S., Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 134, p. 68-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Direct Measurement of Amorphous Solubility

    Stukelj, J., Svanback, S., Agopov, M., Löbmann, Korbinian, Strachan, C. J., Rades, Thomas & Yliruusi, J., 4 Jun 2019, In: Analytical Chemistry. 91, 11, p. 7411-7417

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Dissolution properties of co-amorphous drug-amino acid formulations in buffer and biorelevant media

    Heikkinen, A. T., DeClerck, L., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Laitinen, R., Jul 2015, In: Pharmazie. 70, 7, p. 452-457 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Effect of Drug Loading in Mesoporous Silica on Amorphous Stability and Performance

    Bavnhøj, C. G., Knopp, Matthias Manne & Löbmann, Korbinian, 2024, In: Pharmaceutics. 16, 2, 11 p., 163.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Efflux Inhibitor Bicalutamide Increases Oral Bioavailability of the Poorly Soluble Efflux Substrate Docetaxel in Co-Amorphous Anti-Cancer Combination Therapy

    Bohr, A., Nascimento, T. L., Harmankaya, N., Weisser, J. J., Wang, Y., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 2019, In: Molecules. 24, 2, 13 p., 266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Elucidating the molecular interactions occurring during drug precipitation of weak bases from lipid-based formulations: a case study with cinnarizine and a long chain self-nanoemulsifying drug delivery system

    Sassene, P. J., Mosgaard, M. D., Löbmann, Korbinian, Mu, Huiling, Larsen, F. H., Rades, Thomas & Mullertz, Anette , 2015, In: Molecular Pharmaceutics. 12, 11, p. 4067-4076 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Emerging trends in the stabilization of amorphous drugs

    Laitinen, R., Löbmann, Korbinian, Strachan, C. J., Grohganz, Holger & Rades, Thomas, 30 Aug 2013, In: International Journal of Pharmaceutics. 453, 1, p. 65-79 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations

    Palmelund, H., Eriksen, J. B., Bauer-Brandl, A., Rantanen, Jukka & Löbmann, Korbinian, 2021, In: International Journal of Pharmaceutics: X. 3, 100083.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques

    Knopp, Matthias Manne, Olesen, N. E., Holm, P., Löbmann, Korbinian, Holm, R., Langguth, P. & Rades, Thomas, Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 44-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Exploring the effect of protein secondary structure on the solid state and physical stability of protein-based amorphous solid dispersions

    Zhuo, Xuezhi, Ochner, J., Leng, D., Foderà, Vito & Löbmann, Korbinian, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 198, 8 p., 114274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Floating solid cellulose nanofibre nanofoams for sustained release of the poorly soluble model drug furosemide

    Svagan, A. J., Mullertz, Anette & Löbmann, Korbinian, Nov 2017, In: The Journal of pharmacy and pharmacology. 69, 11, p. 1477-1484 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Formation mechanism of coamorphous drug−amino acid mixtures

    Jensen, K. B. T., Larsen, F. H., Cornett, Claus, Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2015, In: Molecular Pharmaceutics. 12, 7, p. 2484−2492 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Formulating Amorphous Drug Delivery System Using Low-Molecular-Weight Components as Stabilizers

    Löbmann, Korbinian, Laitinen, R., Grohganz, Holger & Rades, Thomas, 2014, In: CRS Newsletter. 31, 3, p. 16-17

    Research output: Contribution to journalJournal articleCommunication

  46. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Glass forming ability of amorphous drugs investigated by continuous cooling- and isothermal transformation

    Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 2016, In: Molecular Pharmaceutics. 13, 9, p. 3318-3325 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glass solution formation in water - In situ amorphization of naproxen and ibuprofen with Eudragit® E PO

    Doreth, M., Löbmann, Korbinian, Grohganz, Holger, Holm, R., Lopez De Diego, H., Rades, Thomas & Priemel, P. A., 1 Feb 2016, In: Journal of Drug Delivery Science and Technology. 34, p. 32–40 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

    Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Hot Melt Coating of Amorphous Carvedilol

    Bannow, J., Koren, L., Salar-Behzadi, S., Löbmann, Korbinian, Zimmer, A. & Rades, Thomas, 2020, In: Pharmaceutics. 12, 6, 13 p., 519.

    Research output: Contribution to journalJournal articleResearchpeer-review

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