Jette Jacobsen

Jette Jacobsen

Associate Professor

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    1. Published

      The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition

      Welling, S. H., Hubálek, F., Jacobsen, Jette, Brayden, D. J., Rahbek, U. L. & Buckley, S. T., Apr 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 86, 3, p. 544-51 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Tenacious and Lubricating Gels as Drug-Carrier and Body Fluids Substitutes

      Vatne, K., Jacobsen, Jette, Baldursdottir, S. G., Pedersen, Anne Marie Lynge, Vilmann, Peter, Dalby, K. D. & Bar-Shalom, Daniel, 2 Nov 2014.

      Research output: Contribution to conference › Poster › Research › peer-review

    3. Published

      An updated and simplified method for bile duct cannulation of rats

      Tønsberg, H., Holm, R., Bjerregaaard, T. G., Jacobsen, Jette & Mullertz, Anette , 2010, In: Laboratory Animals. 44, 4, p. 373-376

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats

      Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats

      Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome

      Treldal, C., Jacobsen, C. B., Mogensen, S., Rasmussen, M., Jacobsen, Jette, Petersen, J., Pedersen, Anne Marie Lynge & Andersen, O., Mar 2016, In: Oral Diseases. 22, 2, p. 123-31 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Characterization of burning mouth syndrome profiles based on response to a local anaesthetic lozenge

      Treldal, C., Petersen, Janne, Mogensen, S., Therkildsen, C., Jacobsen, Jette, Andersen, Ove & Pedersen, Anne Marie Lynge, 2020, In: Oral Diseases. 26, 3, p. 656-669 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery

      Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Swelling of mucoadhesive electrospun chitosan/polyethylene oxide nanofibers facilitates adhesion to the sublingual mucosa

      Stie, Mai Bay, Gätke, J. R., Wan, F., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 15 Aug 2020, In: Carbohydrate Polymers. 242, 10 p., 116428.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Waterborne Electrospinning of α-Lactalbumin Generates Tunable and Biocompatible Nanofibers for Drug Delivery

      Stie, Mai Bay, Corezzi, M., Juncos Bombin, A. D., Ajalloueian, F., Attrill, E., Pagliara, S., Jacobsen, Jette, Chronakis, I. S., Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: ACS Applied Nano Materials. 3, 2, p. 1910–1921

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers

      Stie, Mai Bay, Jones, M., Sørensen, H. O., Jacobsen, Jette, Chronakis, I. S. & Nielsen, Hanne Mørck, 1 Jul 2019, In: Carbohydrate Polymers. 215, p. 253-262

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Mucoadhesive Electrospun Nanofiber-Based Hybrid System with Controlled and Unidirectional Release of Desmopressin

      Stie, Mai Bay, Gätke, J. R., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 2022, In: International Journal of Molecular Sciences. 23, 3, 9 p., 1458.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Multivariate toxicity screening of liposomal formulations on a human buccal cell line

      Smidstad, G., Jacobsen, Jette & Sande, S. A., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 14-22

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Process development for spray drying of sticky pharmaceuticals; case study of mucoad-hesive nicotine microparticles for compressed medicated chewing gum

      Sander, C., Nielsen, H. S., Søgaard, S. R., Jensen, C. S., Yang, Mingshi, Jacobsen, Jette & Rantanen, Jukka, 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 434-437

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement

      Sander, C., Nielsen, Hanne Mørck & Jacobsen, Jette, 31 Dec 2013, In: International Journal of Pharmaceutics. 458, 2, p. 254-61 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration

      Sander, C., Madsen, K. D., Hyrup, B., Nielsen, Hanne Mørck, Rantanen, Jukka & Jacobsen, Jette, Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt A, p. 682-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy: A Randomized, Controlled Trial

      Salale, N., Treldal, C., Mogensen, S., Rasmussen, M., Petersen, Janne, Andersen, Ove & Jacobsen, Jette, 2014, In: Clinical Medicine Insights: Gastroenterology. 7, p. 55-59 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Polymeric microcontainers improve oral bioavailability of furosemide

      Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6 3 p.

      Research output: Contribution to journal › Journal article › Research

    20. Published

      Tabletter med løse ender

      Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6

      Research output: Contribution to journal › Journal article › Research

    21. Published

      The physicochemical properties of preserved and preservative-free latanoprost eye drops and their impact on human conjunctival goblet cells

      Müllertz, O. A. O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihály, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J. A., Utheim, T. P., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, S267

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    22. Published

      Betaxolol Ophthalmic Solution as Alternative Treatment for Patients with Timolol Allergy: A Case Report

      Müllertz, O., Jacobsen, Jette, Thyssen, Jacob Pontoppidan, Horwitz, A. & Kolko, Miriam, 2020, In: Reports — Medical Cases, Images, and Videos. 3, 3, 4 p., 21.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops

      Mullertz, O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihaly, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J., Utheim, T., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: BMJ Open Ophthalmology. 6, 1, 7 p., 000892.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy

      Mogensen, S., Treldal, C., Feldager, E., Pulis, S., Jacobsen, Jette, Andersen, O. & Rasmussen, M., 2012, In: Local and Regional Anesthesia. 5, p. 17-22 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Absorption of Bupivacaine after Administration of a Lozenge as Topical Treatment for Pain from Oral Mucositis

      Mogensen, S., Sverrisdóttir, E., Sveinsdóttir, K., Treldal, C., Jensen, K., Jensen, A. B., Kristensen, C. A., Jacobsen, Jette, Kreilgaard, M., Petersen, J. & Andersen, O., 2017, In: Basic & Clinical Pharmacology & Toxicology. 120, 1, p. 71-78 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Conscious and anaesthetised Göttingen mini-pigs as an in-vivo model for buccal absorption - pH-dependent absorption of metoprolol from bioadhesive tablets

      Meng-Lund, E., Jacobsen, Jette, Andersen, M. B., Jespersen, M. L., Karlsson, J., Garmer, M., Jørgensen, E. B. & Holm, R., May 2014, In: Drug Development and Industrial Pharmacy. 40, 5, p. 604-610 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Azone® decreases the buccal mucosal permeation of Diazepam in a concentration-dependent manner via a reservoir effect

      Meng-Lund, E., Jacobsen, Jette, Jin, L., Janfelt, Christian, Holm, R., Mullertz, Anette & Nicolazzo, J. A., 15 Feb 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1133-1141 103.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Buccal absorption of diazepam is improved when administered in bioadhesive tablets-An in vivo study in conscious Göttingen mini-pigs

      Meng-Lund, E., Jacobsen, Jette, Mullertz, Anette , Jørgensen, E. B. & Holm, R., 30 Sep 2016, In: International Journal of Pharmaceutics. 515, 1-2, p. 125-131 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.

      Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    31. Published

      A mechanistic based approach for enhancing buccal mucoadhesion of chitosan

      Meng-Lund, E., Muff-Westergaard, C., Sander, C., Madelung, P. & Jacobsen, Jette, 30 Jan 2014, In: International Journal of Pharmaceutics. 461, 1-2, p. 280-5 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Polymeric Lids for Microcontainers for Oral Protein Delivery

      Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Are mucin dispersions a barrier to small molecules in oromucosal drug delivery?

      Marxen, E., Mosgaard, M. D., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2017.

      Research output: Contribution to conference › Poster › Research › peer-review

    34. Published

      Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

      Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In: Pharmaceutical Research. 35, 3, 12 p., 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Effect of cryoprotectants for maintaining drug permeability barriers in porcine buccal mucosa

      Marxen, E., Axelsen, M. C., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2016, In: International Journal of Pharmaceutics. 511, 1, p. 599-605 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging

      Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Can freeze protectants preserve the integrity of permeability barriers in porcine buccal mucosa?

      Marxen, E., Axelsen, M., Pedersen, Anne Marie Lynge & Jacobsen, Jette, Jul 2015.

      Research output: Contribution to conference › Poster › Research › peer-review

    38. Published

      Mucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules

      Marxen, E., Mosgaard, M. D., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 121, p. 121-128

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic

      Maher, S., Leonard, T. W., Jacobsen, Jette & Brayden, D. J., 2009, In: Advanced Drug Delivery Reviews. p. 1427-1449

      Research output: Contribution to journal › Review › Research

    40. Published

      Development of an ex vivo retention model simulating bioadhesion in the oral cavity using human saliva and physiologically relevant irrigation media

      Madsen, K. D., Sander, C., Baldursdottir, S., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 20 May 2013, In: International Journal of Pharmaceutics. 448, 2, p. 373-81 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging

      Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs

      Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

      Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In: European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Predicting in vivo performance of fenofibrate amorphous solid dispersions using in vitro non-sink dissolution and dissolution permeation setup

      Lentz, K. A., Plum, J., Steffansen, B., Arvidsson, P. O., Omkvist, D. H., Pedersen, A. J., Sennbro, C. J., Pedersen, G. P. & Jacobsen, Jette, 2021, In: International Journal of Pharmaceutics. 610, 8 p., 121174.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen

      Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33

      Research output: Contribution to journal › Journal article › Research

    47. Published

      Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

      Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Accepted/In press

      Characterizing interregional differences in the rheological properties and composition of rat small intestinal mucus

      Klitgaard, Mette, Jacobsen, Jette, Kristensen, M. N., Berthelsen, R. & Mullertz, Anette , 2024, (Accepted/In press) In: Drug Delivery and Translational Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Polymer coated liposomes for use in the oral cavity - A study of the in vitro toxicity, effect on cell permeability and interaction with mucin

      Klemetsrud, T., Kjøniksen, A., Hiorth, M., Jacobsen, Jette & Smistad, G., 2018, In: Journal of Liposome Research. 28, 1, p. 62–73 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies

      Kleberg, K., Jacobsen, Jette & Mullertz, Anette , 2010, In: Journal of Pharmacy and Pharmacology. 62, 11, p. 1656-1668 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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