Jesper Østergaard

Jesper Østergaard

Professor


  1. 2012
  2. Published

    Modification of concomitant drug release from oil vehicles using drug-prodrug combinations to achieve sustained balanced analgesia after joint installation

    Thing, M., Jensen, S. S., Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2012, In: International Journal of Pharmaceutics. 439, 1-2, p. 246-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Rapid exchange of metal between Zn7-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes

    Pedersen, J. T., Hureau, C., Hemmingsen, Lars Bo Stegeager, Heegaard, N. H. H., Østergaard, Jesper, Vasák, M. & Faller, P., 2012, In: Biochemistry. 51, 8, p. 1697-1706

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix

    Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In: European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    SNEDDS containing poorly water soluble cinnarizine; development and in Vitro characterization of dispersion, digestion and solubilization

    Larsen, A. T., Ogbonna, A., Abu-Rmaileh, R., Abrahmsson, B., Østergaard, Jesper & Mullertz, Anette , 2012, In: Pharmaceutics. 4, 4, p. 641-665

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2011
  7. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging

    Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, H., Aug 2011, In: Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels

    Ye, F., Yaghmur, Anan, Jensen, H., Larsen, Susan Weng, Larsen, C. & Østergaard, Jesper, 17 Jul 2011, In: European Journal of Pharmaceutical Sciences. 43, 4, p. 236-243

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    In vitro and in vivo characteristics of celecoxib in situ formed suspensions for intra-articular administration

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Thomsen, M. H., Jacobsen, Stine, Skonberg, C., Hansen, S. H., Jensen, Henrik Elvang & Larsen, C. S., 2011, In: Journal of Pharmaceutical Sciences. 100, 10, p. 4330-4337 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Characterization of a liposome-based formulation of oxaliplatin using capillary electrophoresis: encapsulation and leakage

    Franzen, U., Nguyen, T. T. N. T., Vermehren, C., Gammelgaard, Bente & Østergaard, Jesper, 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 1, p. 16-22

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Complexation of tauro- and glycoconjugated bile salts with a-cyclodextrin and hydroxypropyl-a-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling

    Holm, R., Schönbeck, C., Askjær, S., Jensen, H., Westh, P. & Østergaard, Jesper, 2011, In: Journal of Separation Science. 34, 22, p. 3221-3230

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cu(II) mediates kineticallyl distinct, non-amyloidogenic aggregation of amyloid-β peptides

    Pedersen, J. T., Østergaard, Jesper, Rozlosnik, N., Gammelgaard, Bente & Heegaard, N. H. H., 2011, In: Journal of Biological Chemistry. 286, 30, p. 26952-26963

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Effects of bile salts on propranolol distribution into liposomes studied by capillary electrophoresis

    Yang, L., Tucker, I. G. & Østergaard, Jesper, 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 56, p. 553-559

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    In situ characterization of lipidic bupivacaine-loaded formulations

    Yaghmur, Anan, Larsen, Susan Weng, Schmitt, M., Østergaard, Jesper, Larsen, C. S., Jensen, H., Urtti, A. & Rappolt, M., 2011, In: Soft Matter. 7, p. 8291-8295

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

    Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Intra-articular injection of morphine to the horse: Establishment of an in vitro-in vivo relationship

    Frost, A. B., Lindegaard, Casper, Larsen, F., Østergaard, Jesper, Larsen, Susan Weng & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 9, p. 1043-1048

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics: parenteral depots for intra-articular administration

    Pedersen, B. T., Østergaard, Jesper, Larsen, Susan Weng, Cornett, Claus, Ankersen, M. & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 1, p. 62-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Physicochemical characterization of a PEGylated liposomal drug formulation using capillary electrophoresis

    Franzen, U., Vermehren, C., Jensen, H. & Østergaard, Jesper, 2011, In: Electrophoresis. 32, 6-7, p. 738-748

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides

    Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  22. Published

    Simultaneous measurement of phosphorus and platinum by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry (SEC-ICPMS) using xenon as reactive collision gas for charaterization of platinum drug liposomes

    Nguyen, T. T. N. T., Stürup, Stefan, Østergaard, Jesper, Franzen, U. & Gammelgaard, Bente, 2011, In: Journal of Analytical Atomic Spectrometry. 26, 7, p. 1466-1473

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2010
  24. Published

    Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples

    Jensen, H. & Østergaard, Jesper, 2010, In: Journal of the American Chemical Society. 132, 12, p. 4070-4071

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Ghrelin-liposome interactions: Characterization of liposomal formulations of an acylated 28-amino acid peptide using CE

    Østergaard, Jesper & Møller, E. H., 2010, In: Electrophoresis. 31, 2, p. 339-345

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Interfacial complexes between a protein and lipophilic ions at an oil - water interface

    Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse

    Frost, A. B., Larsen, F., Østergaard, Jesper, Larsen, Susan Weng, Lindegaard, Casper, Hansen, H. R. & Larsen, C. S., 2010, In: European Journal of Pharmaceutical Sciences. 41, p. 10-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Real-time UV imaging of nicotin release from transdermal patch

    Østergaard, Jesper, Meng-Lund, E., Larsen, Susan Weng, Larsen, C. S., Petersson, K., Lenke, J. & Jensen, H., 2010, In: Pharmaceutical Research. 27, p. 2614-2623

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Stability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensions

    Møller, E. H., Holst, Birgitte, Nielsen, L. H., Pedersen, P. S. & Østergaard, Jesper, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 13-18

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse

    Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    UV-imaging visulaliserer frigivelse af lægemiddelstoffer

    Ye, F., Meng-Lund, E., Yaghmur, Anan, Larsen, Susan Weng, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2010, In: Lægemiddelforskning. 2010, p. 46-48

    Research output: Contribution to journalJournal articleCommunication

  32. 2009
  33. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C., Larsen, Susan Weng, Yaghmur, Anan, Østergaard, Jesper & Jensen, H., Dec 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    In situ formed suspensions for local sustained action of celecoxib following intra-articular administration

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Jacobsen, Stine, Thomsen, M. H., Lindegaard, Casper, Andersen, P. H. & Larsen, C. S., 2009. 2 p.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Binding of low-molecular-weight cationic ligands to chondroitin sulfate as studied by capillary electrophoresis frontal analysis

    Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. R. & Larsen, C. S., 2009, In: Open Analytical Chemistry Journal. 3, p. 16-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis

    Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Effect of a-cyclodextrin on drug distribution studied by electrochemistry at interfaces between immiscible electrolyte solutions

    Deryabina, M., Hansen, S. H., Østergaard, Jesper & Jensen, H., 2009, In: Journal of Physical Chemistry A. 113, p. 7263-7269

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Elektrokemi til karakterisering og kvantitativ analyse af lægemiddelstoffer

    Jensen, H., Deryabina, M., Hansen, S. H. & Østergaard, Jesper, 2009, In: Lægemiddelforskning.

    Research output: Contribution to journalJournal articleResearch

  39. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots

    Larsen, C. S., Larsen, Susan Weng, Jensen, H., Yaghmur, Anan & Østergaard, Jesper, 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295

    Research output: Contribution to journalReviewResearch

  40. Published

    Simultaneous evaluation of ligand binding properies and protein size by electrophoresis and taylor dispersion in capillaries

    Østergaard, Jesper & Jensen, H., 2009, In: Analytical Chemistry. 81, 20, p. 8644-8648

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Use of correction factors in mobility shift affinity capillary electrophoresis for weak analyte - ligand interactions

    Østergaard, Jesper, Jensen, H. & Holm, R., 2009, In: Journal of Separation Science. 32, 10, p. 1712-1721

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2008
  43. Published

    Affinity capillary electrophoresis for identification and investigation of human Gc-globulin (vitamin D-binding protein) and its isoforms interacting with G-actin

    Pedersen, J. T., Østergaard, Jesper, Houen, G. & Heegaard, N. H. H., 2008, In: Electrophoresis. 29, 8, p. 1723-1733

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Analysis of proteins in solution using affinity capillary electrophoresis

    Heegaard, N. H. H., Schou, C. & Østergaard, Jesper, 2008, Affinity chromatography: methods and protocols. Zachariou, M. (ed.). 2 ed. USA: Humana Press, p. 303-338

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  45. Published

    Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing

    Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Development and Industrial Pharmacy. 34, 3, p. 297-304

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Characterization of the complexation of tauro- and glyco-conjugated bile salts with ¿-cyclodextrin and 2-hydroxypropyl-¿-cyclodextrin using affinity capillary electrophoresis

    Holm, R., Hartvig, R. A., Nicolajsen, H. V., Westh, P. & Østergaard, Jesper, 2008, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 61, 1-2, p. 161 - 169

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice

    Murillo-Arbizu, M., González-Peñas, E., Hansen, S. H., Amézqueta, S. & Østergaard, Jesper, 2008, In: Food and Chemical Toxicology. 46, 6, p. 2251-2257

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Drug - liposome distribution phenomena studied by capillary electrophoresis-frontal analysis

    Østergaard, Jesper, Jørgensen, Lene, Thomsen, A. E., Larsen, Susan Weng, Larsen, C. S. & Jensen, H., 2008, In: Electrophoresis. 29, 16, p. 3320 - 3324

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    In vitro assessment of lidocaine release from aqueous and oil solutions and from preformed and in situ formed aqueos and oil suspensions. Parenteral depots for intra-articular administration

    Pedersen, B. T., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Delivery. 15, 1, p. 23-30

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Intra-articular depot formulation principles: role in the management of postoperative pain and arthritic disorders

    Larsen, C. S., Østergaard, Jesper, Larsen, Susan Weng, Jensen, H., Jacobsen, Stine, Lindegaard, Casper & Andersen, P. H., 2008, In: Journal of Pharmaceutical Sciences. 97, 11, p. 4622-4654 33 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Intra-articular drug disapperance kinetics: Reducing the number of in vivo experiments from establishment of an in vitro-in vivo correlation?

    Frost, A. B., Jacobsen, Stine, Thomsen, M. H., Lindegaard, Casper, Larsen, Susan Weng, Østergaard, Jesper, Andersen, P. H. & Larsen, C. S., 2008. 1 p.

    Research output: Contribution to conferencePosterResearch

  52. Published

    Karakterisering af lægemiddelstof-liposom-vekselvirkninger i et kapillar

    Østergaard, Jesper, Franzen, U., Møller, E. H., Jørgensen, Lene, Larsen, C. S. & Jensen, H., 2008, In: Dansk Kemi. 89, 8, p. 27-29

    Research output: Contribution to journalJournal articleResearch

  53. Published

    Nye depotlægemidler til injektion i gigtramte led: kan laboratoriemodeller reducere antallet af dyreforsøg

    Frost, A. B., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Lægemiddelforskning. p. 46-48

    Research output: Contribution to journalJournal articleCommunication

  54. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds

    Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2007
  57. Published

    Application of retention factors in affinity electrokinetic chromatography and capíllary electrophoresis

    Østergaard, Jesper, 2007, In: Analytical Sciences. 23, 4, p. 489-492

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published
  59. Published

    Bioreversible derivatives of phenol. 2. Reactivity of carbonoate esters with fatty acid-like structures towards hydrolysis in aqueous solutions

    Østergaard, Jesper & Larsen, C. S., 2007, In: Molecules. 12, 10, p. 2396-2412

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    CE frontal analysis based on simultaneous UV and contactless conductivity detection: a general setup for studying noncovalent interactions

    Jensen, H., Østergaard, Jesper, Thomsen, A. E. & Hansen, S. H., 2007, In: Electrophoresis. 28, 3, p. 322-327

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    CE frontal analysis employing contactless conductivity detection for determination of CMCs of non-UV absorbing charged surfactants

    Jensen, H., Østergaard, Jesper & Hansen, S. H., 2007, In: Electrophoresis. 28, 17, p. 2975-2980

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Complexation of tauro- and glyco-conjugated bile salts with three neutral ß-CDs studied by ACE

    Holm, R., Nicolajsen, H. V., Hartvig, R. A., Westh, P. & Østergaard, Jesper, 2007, In: Electrophoresis. 28, 20, p. 3745-3752

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Controlled release - macromolecular prodrugs

    Larsen, C. S., Østergaard, Jesper & Larsen, Susan Weng, 2007, Prodrugs: challenges and rewards. Stella, V. J., Borchardt, R. T., Hageman, M. J., Oliyai, R., Maag, H. & Tilley, J. W. (eds.). New York: Springer, p. 379-416

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  64. Published

    Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model

    Larsen, Susan Weng, Østergaard, Jesper, Poulsen, S., Schulz, B. & Larsen, C. S., 2007, In: European Journal of Pharmaceutical Sciences. 31, 3-4, p. 172-179

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Liposomer i lægemiddelforskning

    Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15

    Research output: Contribution to journalJournal articleCommunication

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