Hanne Mørck Nielsen
Professor
Drug Delivery and Biophysics of Biopharmaceuticals
Universitetsparken 2
2100 København Ø
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Biologiske lægemidler - fra molekyle til medicin
Nielsen, Hanne Mørck, Foged, Camilla, Jørgensen, Lene & Frøkjær, Sven, 2013, In: Lægemiddelforskning. p. 12-14Research output: Contribution to journal › Journal article › Research
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Effect of oil-in-water emulsions on 5-aminolevulinic acid uptake and metabolism to PpIX in cultured MCF-7 cells
Nielsen, Hanne Mørck, Aemisegger, C., Burmeister, G., Schuchter, U. & Gander, B., 2004, In: Pharmaceutical Research. 21, 12, p. 2253-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ciprofloxacin-loaded sodium alginate/poly (lactic-co-glycolic acid) electrospun fibrous mats for wound healing
Nielsen, Hanne Mørck, 2018, In: European Journal of Pharmaceutics and Biopharmaceutics.Research output: Contribution to journal › Journal article › Research › peer-review
Biologiske lægemidler - fra molekyle til medicin
Nielsen, Hanne Mørck, Foged, C., Jørgensen, L. & Frøkjær, S., 2013, In: Lægemiddelforskning. p. 12-14Research output: Contribution to journal › Journal article › Research
Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers
Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, H. & Foged, C., 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Challenges in Delivery of Biopharmaceuticals; the Need for Advanced Delivery Systems
Nielsen, Hanne Mørck & Jørgensen, Lene, 11 Dec 2009, Delivery Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and Vaccines. John Wiley & Sons, Ltd, p. 1-8 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TR146 cells grown on filters as a model of human buccal epithelium: permeability of fluorescein isothiocyanate-labelled dextrans in the presence of sodium glycocholate
Nielsen, Hanne Mørck, Verhoef, J. C., Ponec, M. & Rassing, M. R., 1999, In: Journal of Controlled Release. 60, 2-3, p. 223-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Drug delivery studies in Caco-2 monolayers. IV. Ethyl glycoside esters as a novel type of absorption enhancers.
Nielsen, Hanne Mørck, Brøndsted, H., Frøkjær, Sven & Hovgaard, L., 1996, In: STP pharma sciences. p. 157-161Research output: Contribution to journal › Journal article › Research › peer-review
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Immunity by formulation design: induction of high CD8+ T-cell responses by poly (I:C) incorporated into the CAF01 adjuvant via a double emulsion method
Nordly, P. J., Rose, F., Christensen, D., Nielsen, Hanne Mørck, Andersen, P., Agger, E. M. & Foged, Camilla, 2011, In: Journal of Controlled Release. 150, 3, p. 307-317Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators
Nordly, P. J., Foged, Camilla, Christensen, D., Lindenstrøm, T., Nielsen, Hanne Mørck & Agger, E., 2010.Research output: Contribution to conference › Poster › Research
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Innovativt nanopartikeldesign bag skræddersyede vacciner
Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Lægemiddelforskning. p. 19-21Research output: Contribution to journal › Journal article › Research
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Incorporation of the TLR4 agonist monophosphoryl lipid A into the bilayer of DDA/DTDB liposomes : physico-chemical characterization and induction of CD8+ T-Cell responses in vivo
Nordly, P. J., Agger, E. M., Andersen, P., Nielsen, Hanne Mørck & Foged, Camilla, 2011, In: Pharmaceutical Research. 28, 3, p. 553-562Research output: Contribution to journal › Journal article › Research › peer-review
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Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators
Nordly, P. J., Madsen, H. B., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Expert Opinion on Drug Delivery. 6, 7, p. 1-16Research output: Contribution to journal › Review › Research
Innovativt nanopartikeldesign bag skræddersyede vacciner
Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, C., 2009, In: Lægemiddelforskning. p. 19-21Research output: Contribution to journal › Journal article › Research
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A synthetic mycobacterial monomycoloyl glycerol analogue stabilizes DDA liposomes
Nordly, P. J., Pedersen, E. A., Khiljii, T. S., Agger, E. M., Jørgensen, Lene, Nielsen, Hanne Mørck, Korsholm, K. S., Franzyk, Henrik & Foged, Camilla, 2010, In: CRS Newsletter. 27, 2, p. 12 14 p.Research output: Contribution to journal › Journal article › Research
Status and future prospects of lipid-based particulate delivery systems as vaccine adjuvants and their combination with immunostimulators
Nordly, P. J., Madsen, H. B., Nielsen, Hanne Mørck & Foged, C., 2009, In: Expert Opinion on Drug Delivery. 6, 7, p. 1-16Research output: Contribution to journal › Review › Research
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Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo
Nordly, P. J., Korsholm, K. S., Pedersen, E. A., Khilji, T. S., Franzyk, Henrik, Jørgensen, Lene, Nielsen, Hanne Mørck, Agger, E. M. & Foged, Camilla, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators
Nordly, P. J., Foged, C., Christensen, D., Lindenstrøm, T., Nielsen, Hanne Mørck & Agger, E., 2010.Research output: Contribution to conference › Poster › Research
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Antimicrobial, hemolytic, and cytotoxic activities of β-peptoid- peptide hybrid oligomers: Improved properties compared to natural AMPs (ChemBioChem (2010) 11, (152-160))
Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 16 Aug 2010, In: ChemBioChem. 11, 12, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Antimicrobial, hemolytic, and cytotoxic activities of ß-peptoid-peptide hybrid oligomers: Improved properties compared to natural AMPs
Olsen, Christian Adam, Ziegler, H. L., Nielsen, Hanne Mørck, Frimodt-Møller, N., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In: ChemBioChem. 11, 10, p. 1356-1360Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery
Panou, D. A., Diedrichsen, Ragna Guldsmed, Kristensen, Mie & Nielsen, Hanne Mørck, 2022, Cell Penetrating Peptides: Methods and Protocols. Langel, Ü. (ed.). Springer, p. 371-384 (Methods in Molecular Biology, Vol. 2383).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison
Panou, D. A., Pedersen, Stine Helene Falsig, Kristensen, Mie & Nielsen, Hanne Mørck, 2023, In: Frontiers in Drug Delivery. 3, 16 p., 1221628.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of immune stimulating complex matrices and immune stimulating complexes in suspension determined by small-angle X-ray scattering
Pedersen, J. S., Oliveira, C. L. P. D., Madsen, H. B., Arleth, Lise, Manniche, S., Kirkby, N. & Nielsen, Hanne Mørck, 2012, In: Biophysical Journal. 102, 10, p. 2372-2380Research output: Contribution to journal › Journal article › Research › peer-review
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The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium
Portero, A., Remuñán-López, C. & Nielsen, Hanne Mørck, 2002, In: Pharmaceutical Research. 19, 2, p. 169-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Poly(ethylene carbonate)-containing polylactic acid microparticles with rifampicin improve drug delivery to macrophages
Priemel, P. A., Wang, Y., Bohr, A., Water, J. J., Yang, Mingshi & Nielsen, Hanne Mørck, Aug 2018, In: Journal of Pharmacy and Pharmacology. 70, 8, p. 1009-1021Research output: Contribution to journal › Journal article › Research › peer-review
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Additive manufacturing of polymeric scaffolds for biomimetic cell membrane engineering
Rovira, D. S., Nielsen, Hanne Mørck, Taboryski, R. & Bunea, A., 2021, In: Materials and Design. 201, 11 p., 109486.Research output: Contribution to journal › Journal article › Research › peer-review
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Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement
Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro
Rønholt, Stine, Kristensen, Mie & Nielsen, Hanne Mørck, 2015, Cell-penetrating peptides : Methods and Protocols. Langel, Ü. (ed.). Vol. 1324. p. 261-277 17 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro
Rønholt, Stine, Kristensen, Mie & Nielsen, Hanne Mørck, 2015, In: Methods in Molecular Biology. 1324, p. 261-277 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of spray dried bioadhesive metformin microparticles for oromucosal administration
Sander, C., Madsen, K. D., Hyrup, B., Nielsen, Hanne Mørck, Rantanen, Jukka & Jacobsen, Jette, Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt A, p. 682-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Buccal delivery of metformin: TR146 cell culture model evaluating the use of bioadhesive chitosan discs for drug permeability enhancement
Sander, C., Nielsen, Hanne Mørck & Jacobsen, Jette, 31 Dec 2013, In: International Journal of Pharmaceutics. 458, 2, p. 254-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites
Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
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Non-aqueous topical compositions comprising a halogenated salicylanilide
Sommer, M., Li, P., Frandsen, C. H., Nielsen, Hanne Mørck, Priemel, P. A. & Rades, Thomas, 2019, Patent No. US20190151231A1Research output: Patent
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Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides
Steffensen, S. L., Møller, E. H., Franzyk, Henrik, Jensen, M. G., Alm, M. & Nielsen, Hanne Mørck, 2013.Research output: Contribution to conference › Poster › Research › peer-review
Silicone embedded nanogels for prolonged resistance against biofilm formation
Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, H. & Nielsen, Hanne Mørck, 2014.Research output: Contribution to conference › Poster › Research › peer-review
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Sustained prevention of biofilm formation on a novel silicone matrix suitable for medical devices
Steffensen, S. L., Merete H., V., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 94, p. 305-311Research output: Contribution to journal › Journal article › Research › peer-review
Novel Silicone Composite for Prolonged Release of Antimicrobial Peptides
Steffensen, S. L., Møller, E. H., Franzyk, H., Jensen, M. G., Alm, M. & Nielsen, Hanne Mørck, 2013.Research output: Contribution to conference › Poster › Research › peer-review
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Soft hydrogels interpenetrating silicone – a polymer network for drug releasing medical devices
Steffensen, S. L., Merete H., V., Møller, E. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2016, In: Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 104, 2, p. 402-410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Silicone embedded nanogels for prolonged resistance against biofilm formation
Steffensen, S. L., Vestergaard, M. H., Jensen, M. G., Alm, M., Franzyk, Henrik & Nielsen, Hanne Mørck, 2014.Research output: Contribution to conference › Poster › Research › peer-review
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Bioactive protein-based nanofibers interact with intestinal biological components resulting in transepithelial permeation of a therapeutic protein
Stephansen, K., García-Díaz, M., Jessen, F., Chronakis, I. S. & Nielsen, Hanne Mørck, 10 Nov 2015, In: International Journal of Pharmaceutics. 495, 1, p. 58-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions between Surfactants in Solution and Electrospun Protein Fibers: Effects on Release Behavior and Fiber Properties
Stephansen, K., García-Díaz, M., Jessen, F., Chronakis, I. S. & Nielsen, Hanne Mørck, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 748-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery
Stie, Mai Bay, Öblom, H., Hansen, Anders Christian Nørgaard, Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.Research output: Contribution to journal › Journal article › Research › peer-review
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Swelling of mucoadhesive electrospun chitosan/polyethylene oxide nanofibers facilitates adhesion to the sublingual mucosa
Stie, Mai Bay, Gätke, J. R., Wan, F., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 15 Aug 2020, In: Carbohydrate Polymers. 242, 10 p., 116428.Research output: Contribution to journal › Journal article › Research › peer-review
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Waterborne Electrospinning of α-Lactalbumin Generates Tunable and Biocompatible Nanofibers for Drug Delivery
Stie, Mai Bay, Corezzi, M., Juncos Bombin, A. D., Ajalloueian, F., Attrill, E., Pagliara, S., Jacobsen, Jette, Chronakis, I. S., Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: ACS Applied Nano Materials. 3, 2, p. 1910–1921Research output: Contribution to journal › Journal article › Research › peer-review
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Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers
Stie, Mai Bay, Jones, M., Sørensen, H. O., Jacobsen, Jette, Chronakis, I. S. & Nielsen, Hanne Mørck, 1 Jul 2019, In: Carbohydrate Polymers. 215, p. 253-262Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoadhesive Electrospun Nanofiber-Based Hybrid System with Controlled and Unidirectional Release of Desmopressin
Stie, Mai Bay, Gätke, J. R., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 2022, In: International Journal of Molecular Sciences. 23, 3, 9 p., 1458.Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclodextrins: efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems
Stojanov, M., Nielsen, Hanne Mørck & Larsen, K. L., 2012, In: International Journal of Pharmaceutics. 422, 1-2, p. 349-355Research output: Contribution to journal › Journal article › Research › peer-review
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The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering
Streck, S., Clulow, A. J., Nielsen, Hanne Mørck, Rades, Thomas, Boyd, B. J. & McDowell, A., 1 Nov 2019, In: Journal of Colloid and Interface Science. 555, p. 438-448 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions of Cell-Penetrating Peptide-Modified Nanoparticles with Cells Evaluated Using Single Particle Tracking
Streck, S., Bohr, S. S., Birch, D., Rades, Thomas, Hatzakis, Nikos, McDowell, A. & Nielsen, Hanne Mørck, 2021, In: ACS Applied Bio Materials. 4, 4, p. 3155-3165 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides of different architectures
Streck, S., Neumann, H., Nielsen, Hanne Mørck, Rades, Thomas & McDowell, A., Dec 2019, In: International Journal of Pharmaceutics: X. 1, 9 p., 100030.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299091
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Characterization of PTH-CPP fusion peptides for oral delivery
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published