Hanne Mørck Nielsen

Hanne Mørck Nielsen

Professor

ORCID: 0000-0002-7285-9100

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  1. Published

    Assessment of mucoadhesion using small deformation rheology revisited

    Rønholt, Stine, Vissing, K. J. & Nielsen, Hanne Mørck, Apr 2017, In: Nordic Rheology Society Annual Transactions. 25, p. 63 7 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  2. Published

    Animal models for evaluation of oral delivery of biopharmaceuticals

    Rønholt, Stine, Nielsen, L. H. & Nielsen, Hanne Mørck, Dec 2017, In: Journal of Controlled Release. 268, p. 57-71 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

    Rønholt, Stine, Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, Hanne Mørck, 1 Jan 2019, In: Drug Delivery. 26, 1, p. 532-541

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Nielsen, Hanne Mørck & Hansen, Paul Robert, 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  5. Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa

    Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, Hanne Mørck & Hansen, P. R., 7 Jul 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  6. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

    Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, Hanne Mørck, Damborg, Peter Panduro & Hansen, Paul Robert, 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Peptide-peptoid hybrids active against methicillin-resistant Staphylococci and Pseudomonas aeruginosa

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca, Nielsen, Hanne Mørck & Hansen, Paul Robert, 7 Jul 2013.

    Research output: Contribution to conference › Poster › Research › peer-review

  8. AMP mimics with bactericidal activity against Staphylococci and Pseudomonas as novel drugs for topical use in veterinary medicine

    Greco, I., Damborg, P. P., Guardabassi, L., Nielsen, Hanne Mørck & Hansen, P. R., 4 Jun 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  9. Published

    Antimicrobial activity of GN peptides and their mode of action

    Godballe, T., Mojsoska, B., Nielsen, Hanne Mørck & Jenssen, H., 13 Dec 2015, In: Biopolymers. 106, 2, p. 172–183 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The role of mucus as an invisible cloak to transepithelial drug delivery by nanoparticles

    García-Díaz, M., Birch, D., Wan, F. & Nielsen, Hanne Mørck, Jan 2018, In: Advanced Drug Delivery Reviews. 124, p. 107-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Improved insulin loading in poly (lactic-co-glycolic) acid (PLGA) nanoparticles upon self-assembly with lipids

    Garcia Diaz, M., Foged, Camilla & Nielsen, Hanne Mørck, 2015, In: International Journal of Pharmaceutics. 482, p. 84-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen

    Foged, C., Ingvarsson, P. T., Follmann, F., Christensen, D. & Nielsen, Hanne Mørck, 2013, In: Lægemiddelforskning. 2013, p. 41-43

    Research output: Contribution to journal › Journal article › Research

  13. Published

    Genetisk nanomedicin til behandling af leddegigt

    Foged, Camilla, Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  14. Published

    Cell-penetrating peptides for cytosolic delivery of biomacromolecules

    Foged, Camilla, Jing, X. & Nielsen, Hanne Mørck, 2010, Organelle-specific pharmaceutical nanotechnology. Weissig, V. & D'Souza, G. G. M. (eds.). Hoboken: Wiley, p. 403-432

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  15. Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)

    Foged, C., Nielsen, Hanne Mørck & Frøkjær, S., 2007, In: Journal of Liposome Research. 17, 3-4

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides

    Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA

    Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931

    Research output: Patent

  18. Published

    Vaccination i slimhinderne skal forhindre sygdomsfremkaldende mikroorganismer at nå ind i kroppen

    Foged, Camilla, Ingvarsson, P. T., Follmann, F., Christensen, D. & Nielsen, Hanne Mørck, 2013, In: Lægemiddelforskning. 2013, p. 41-43

    Research output: Contribution to journal › Journal article › Research

  19. Published

    Cell-penetrating peptides for drug delivery across membrane barriers

    Foged, Camilla & Nielsen, Hanne Mørck, 2008, In: Expert Opinion on Drug Delivery. 5, 1, p. 105-17 12 p.

    Research output: Contribution to journal › Review › Research

  20. Published

    Phospholipase A2 sensitive liposomes for delivery of small interfering RNA (siRNA)

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Journal of Liposome Research. 17, 3-4

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

    Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Genetisk nanomedicin til behandling af leddegigt

    Foged, C., Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In: Lægemiddelforskning. p. 7-9

    Research output: Contribution to journal › Journal article › Communication

  23. Cell-penetrating peptides for cytosolic delivery of biomacromolecules

    Foged, C., Jing, X. & Nielsen, Hanne Mørck, 2010, Organelle-specific pharmaceutical nanotechnology. Weissig, V. & D'Souza, G. G. M. (eds.). Hoboken: Wiley, p. 403-432

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  24. Published

    Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: A comparative study with epithelial cell cultures

    Foerg, C., Weller, K. M., Rechsteiner, H., Nielsen, Hanne Mørck, Fernandez-Carneado, J., Brunisholz, R., Giralt, E. & Merkle, H. P., 2008, In: The AAPS Journal. 10, 2, p. 349-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Metabolic cleavage and translocation efficiency of selected cell penetrating peptides: A comparative study with epithelial cell cultures

    Foerg, C., Weller, K. M., Rechsteiner, H., Nielsen, Hanne Mørck, Fernandez-Carneado, J., Brunisholz, R., Giralt, E. & Merkle, H. P., 2008, In: The AAPS Journal. 10, 2, p. 349-359

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy

    Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.

    Research output: Contribution to conference › Poster › Research

  27. Published

    EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide

    Eissa, N. G., Sayers, E. J., Birch, D., Patel, S. G., Tsai, Y. H., Nielsen, Hanne Mørck & Jones, A. T., 8 Jan 2020, In: Biochemical Journal. 477, 1, p. 45-60 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate

    Eirheim, H. U., Bundgaard, C. & Nielsen, Hanne Mørck, 2004, In: Toxicology in Vitro. 18, 5, p. 649-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Carrier peptide interactions with liposome membranes induce reversible clustering by surface adsorption and shape deformation

    Diedrichsen, Ragna Guldsmed, Vetri, V., Prévost, S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Journal of Colloid and Interface Science. 650, Part B, p. 1821-1832

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Revealing the importance of carrier-cargo association in delivery of insulin and lipidated insulin

    Diedrichsen, Ragna Guldsmed, Rønholt, Stine, Werner, U., Besenius, M., Leberer, E., Kristensen, Mie & Nielsen, Hanne Mørck, 2021, In: Journal of Controlled Release. 338, p. 8-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Stereochemistry and Intermolecular Interactions Influence Carrier Peptide-Mediated Insulin Delivery

    Diedrichsen, Ragna Guldsmed, Tuelung, P. S., Foderà, Vito & Nielsen, Hanne Mørck, 2023, In: Molecular Pharmaceutics. 20, 2, p. 1202–1212

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, P. P., Skindersø, M. E., Hansen, P. R., Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, L., Aug 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  33. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, Peter Panduro, Skindersø, M. E., Hansen, Paul Robert, Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, Luca, Aug 2012.

    Research output: Contribution to conference › Poster › Research › peer-review

  34. Published

    Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Studies towards improved stability and permeability of a cell-penetrating peptide

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, H. & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  36. Published

    Studies towards improved stability and permeability of a cell-penetrating peptide

    Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  37. Published

    Preparation and characterization of poly (DL-lactide-co-glycolide) nanoparticles for siRNA delivery

    Cun, D., Foged, Camilla, Yang, Mingshi, Frøkjær, Sven & Nielsen, Hanne Mørck, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 70-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Polymeric nanocarriers for siRNA delivery: challenges and future prospects

    Cun, D., Jensen, L. B., Nielsen, Hanne Mørck, Moghimi, S. M. & Foged, Camilla, 2008, In: Journal of Biomedical Nanotechnology. 4, 3, p. 258-275

    Research output: Contribution to journal › Review › Research

  39. Polymeric nanocarriers for siRNA delivery: challenges and future prospects

    Cun, D., Jensen, L. B., Nielsen, Hanne Mørck, Moghimi, S. M. & Foged, C., 2008, In: Journal of Biomedical Nanotechnology. 4, 3, p. 258-275

    Research output: Contribution to journal › Review › Research

  40. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, Camilla & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, C. & Nielsen, Hanne Mørck, 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

    Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Evaluation of carrier-mediated siRNA delivery: lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA

    Colombo, S., Nielsen, Hanne Mørck & Foged, Camilla, 11 Jan 2013, In: Journal of Controlled Release. 166, 3, p. 220-226 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Solid-phase route to Fmoc-protected cationic amino acid building blocks

    Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Solid lipid particles for oral delivery of peptide and protein drugs I - Elucidating the release mechanism of lysozyme during lipolysis

    Christophersen, P. C. B., Zhang, L., Yang, Mingshi, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2 Aug 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, part A, p. 473-480

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II - The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation

    Christophersen, P. C., Zhang, L., Mullertz, Anette , Nielsen, Hanne Mørck, Yang, Mingshi & Mu, Huiling, 13 Mar 2014, In: Pharmaceutical Research. 31, 9, p. 2420-28 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Characterization of particulate drug delivery systems for oral delivery of Peptide and protein drugs

    Christophersen, P. C., Fano, M., Saaby, Lasse, Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, 2015, In: Current Pharmaceutical Design. 21, 19, p. 2611-28 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

    Christophersen, P. C., Birch, D., Saarinen, J., Isomäki, A., Nielsen, Hanne Mørck, Yang, Mingshi, Strachan, C. J. & Mu, Huiling, 10 Jan 2015, In: Journal of Controlled Release. 197, p. 111-120 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin

    Christophersen, P. C., Vaghela, D., Mullertz, Anette , Yang, Mingshi, Nielsen, Hanne Mørck & Mu, Huiling, Jul 2014, In: A A P S Journal. 16, 4, p. 875-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1299091