Camilla Foged

Camilla Foged

Professor

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    ORCID: 0000-0003-2812-5588

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    1. Published

      Optimizing the Intracellular Delivery of Therapeutic Anti-inflammatory TNF-α siRNA to Activated Macrophages Using Lipidoid-Polymer Hybrid Nanoparticles

      Lokras, Abhijeet, Thakur, A., Wadhwa, A., Thanki, K., Franzyk, Henrik & Foged, Camilla, 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 14 p., 601155.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Opportunities and Challenges in the Delivery of mRNA-based Vaccines

      Wadhwa, A., Aljabbari, A., Lokras, Abhijeet, Foged, Camilla & Thakur, A., 28 Jan 2020, In: Pharmaceutics. 12, 2, 27 p., 102.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      One-Step Production of Protein-Loaded PLGA Microparticles via Spray Drying Using 3-Fluid Nozzle

      Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 19 Feb 2014, In: Pharmaceutical Research. 31, 8, p. 1969-1977 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Omikron: Sådan justerer forskerne en mRNA-vaccine

      Foged, Camilla, 3 Dec 2021, In: ForskerZonen. 2021, december

      Research output: Contribution to journal › Journal article › Communication

    5. Published

      Nebulised lipid-polymer hybrid nanoparticles for the delivery of a therapeutic anti-inflammatory microRNA to bronchial epithelial cells

      Vencken, S., Foged, Camilla, Ramsey, J. M., Sweeney, L., Cryan, S., MacLoughlin, R. J. & Greene, C. M., Apr 2019, In: ERJ Open Research. 5, 2, 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Nanoparticles for mucosal vaccine delivery

      Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Woodhead Publishing, p. 603-646 44 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    7. Published

      Nanoparticles for mucosal vaccine delivery

      Thakur, A. & Foged, Camilla, 2020, Nanoengineered Biomaterials for Advanced Drug Delivery. Mozafari, M. (ed.). 1 ed. Elsevier

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    8. Published

      Nanoparticle-mediated delivery of the antimicrobial peptide plectasin against Staphylococcus aureus in infected epithelial cells

      Water, J. J., Smart, S., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 18 Feb 2015, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 92, p. 65-73 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA

      Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931

      Research output: Patent

    10. Published

      Nano-self-assemblies based on synthetic analogues of mycobacterial monomycoloyl glycerol and DDA: Supramolecular structure and adjuvant efficacy

      Martin-Bertelsen, Birte, Korsholm, K. S., Christensen, D., Franzyk, Henrik, Yaghmur, Anan & Foged, Camilla, 2016, In: Molecular Pharmaceutics. 13, 8, p. 2771-2781 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01

      Christensen, D., Allesø, M., Rosenkrands, I., Rantanen, Jukka, Foged, Camilla, Agger, E. M., Andersen, P. & Nielsen, Hanne Mørck, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 914-920

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Mucosal drug delivery: barriers, in vitro models and formulation strategies

      Bøgh, M., Foged, Camilla, Mullertz, Anette & Nielsen, Hanne Mørck, 2013, In: Journal of Drug Delivery Science and Technology. 23, 4, p. 383-391

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      Molecular characterization of the interaction between siRNA and PAMAM G7 dendrimers by SAXS, ITC, and molecular dynamics simultations

      Jensen, L. B., Mortensen, Kell, Pavan, G. M., Kasimova, M. R., Jensen, D. K., Gadzhyeva, V., Nielsen, Hanne Mørck & Foged, Camilla, 2010, In: Biomacromolecules. 11, 12, p. 3571-3577

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Molecular Characterization of the Interaction between siRNA and PAMAM G7 Dendrimers by SAXS, ITC, and Molecular Dynamics Simulations

      Jensen, L. B., Mortensen, Kell, Pavan, G. M., Kasimova, M. R., Jensen, D. K., Gadzhyeva, V., Nielsen, Hanne Mørck & Foged, Camilla, Dec 2010, In: Biomacromolecules. 11, 12, p. 3571-3577

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Modulation of the adjuvant activity of DDA/TDB liposomes with immunostimulators

      Nordly, P. J., Foged, Camilla, Christensen, D., Lindenstrøm, T., Nielsen, Hanne Mørck & Agger, E., 2010.

      Research output: Contribution to conference › Poster › Research

    16. Published

      Modulating protein release profiles by incorporating hyaluronic acid into PLGA microparticles Via a spray dryer equipped with a 3-fluid nozzle

      Wan, F., Maltesen, M. J., Andersen, S. K., Bjerregaard, S., Baldursdottir, S. G., Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, Nov 2014, In: Pharmaceutical Research. 31, 11, p. 2940-51 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Microfluidics-based self-assembly of peptide-loaded microgels: Effect of three dimensional (3D) printed micromixer design

      Borro, B. C., Bohr, A., Bucciarelli, S., Bøtker, Johan Peter, Foged, Camilla, Rantanen, Jukka & Malmsten, Martin, 7 Mar 2019, In: Journal of Colloid and Interface Science. 538, p. 559-568 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptoids and lipid bilayers - effect of length, charge and N-terminal end group

      Jing, X., Simonsen, A. H., Kasimova, M. R., Franzyk, Henrik, Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23/24, p. 1109

      Research output: Contribution to journal › Conference abstract in journal › Research

    19. Published

      Microcalorimetric and spectroscopic studies on the mechanism of interaction between novel peptidomimetics and lipid bilayers

      Nielsen, Hanne Mørck, Jing, X., Simonsen, A., Kasimova, M. R., Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2010, In: Journal of Peptide Science. 16, s1, p. 151 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    20. Published

      Method of manufacturing CAF®09 liposomes affects immune responses induced by adjuvanted subunit proteins

      Thakur, A., Wadhwa, A., Lokras, Abhijeet, Amanda Oest Müllertz, O., Christensen, D., Franzyk, Henrik & Foged, Camilla, 2023, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 189, p. 84-97

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: effects of hydrogen bonding and α-chirality in the β-peptoid residues

      Jing, X., Yang, M., Kasimova, M. R., Malmsten, M., Franzyk, Henrik, Jørgensen, Lene, Foged, Camilla & Nielsen, Hanne Mørck, 2012, In: BBA General Subjects. 1818, 11, p. 2660-2668 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Mechanistic profiling of the siRNA delivery dynamics of lipid-polymer hybrid nanoparticles

      Colombo, S., Cun, D., Remaut, K., Bunker, M., Zhang, J., Martin-Bertelsen, Birte, Yaghmur, Anan, Braeckmans, K., Nielsen, Hanne Mørck & Foged, Camilla, 10 Mar 2015, In: Journal of Controlled Release. 201, p. 22-31 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration

      Thanki, K., van Eetvelde, D., Geyer, A., Fraire, J., Hendrix, R., Van Eygen, H., Putteman, E., Sami, H., de Souza Carvalho-Wodarz, C., Franzyk, Henrik, Nielsen, Hanne Mørck, Braeckmans, K., Lehr, C., Ogris, M. & Foged, Camilla, 2019, In: Journal of controlled release : official journal of the Controlled Release Society. 310, p. 82-93

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Mechanism of Action of Lung Damage Caused by a Nanofilm Spray Product

      Larsen, S. T., Dallot, C., Larsen, Susan Weng, Rose, F., Poulsen, Steen Seier, Nørgaard, A. W., Hansen, J. S., Sørli, J. B., Nielsen, G. D. & Foged, Camilla, 25 May 2014, In: Toxicological Sciences. 140, 2, p. 436-444 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Malaria biomimetic for tumor targeted drug delivery

      Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling

      Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model

      Te Boekhorst, B. C. M., Jensen, L. B., Colombo, S., Varkouhi, A. K., Schiffelers, R. M., Lammers, T., Storm, G., Nielsen, Hanne Mørck, Strijkers, G. J., Foged, Camilla & Nicolay, K., 2012, In: Journal of controlled release : official journal of the Controlled Release Society. 161, 3, p. 772-80 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Loading of an antimicrobial peptide into PLGA nanoparticles increases its efficacy against intracellular Staphylococcus aureus infection in the Calu-3 bronchial epithelial cell line

      Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2013.

      Research output: Contribution to conference › Poster › Research › peer-review

    29. Published

      Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test

      Foged, Camilla, Nielsen, Hanne Mørck & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 160-166

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators

      Schmidt, S. T., Foged, Camilla, Korsholm, K. S., Rades, Thomas & Christensen, D., 10 Mar 2016, In: Pharmaceutics. 8, 1, 22 p., 7.

      Research output: Contribution to journal › Review › Research › peer-review

    31. Published

      Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model

      Jansen, M. A. A., Klausen, L. H., Thanki, K., Lyngsø, J., Skov Pedersen, J., Franzyk, Henrik, Nielsen, Hanne Mørck, van Eden, W., Dong, M., Broere, F., Foged, Camilla & Zeng, X., 2019, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 142, p. 38-48

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Lipid-polymer hybrid nanoparticles (LPNs) for efficient pulmonary delivery of nucleic acids: Lessons learnt from quality-by-design based optimization, immunogenicity studies, in vitro release experiments, in vivo biodistribution and efficacy studies

      Thanki, K., Thakur, A., de Groot, A. M., Geyer, A., Fraire, J., Falkenberg, E., Van Eygen, H., Putteman, E., Van Bijnen, D. C. J., Zeng, X., Sami, H., Gehrig, S., Justesen, S., Franzyk, H., Broere, F., van Eden, W., Sijts, A. J. A. M., Ogris, M., Nielsen, H. M., Braeckmans, K. & 1 others, Foged, Camilla, 2018.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    33. Published

      Lipid-based formulations for siRNA delivery

      Foged, Camilla, Vader, P. & Schiffelers, R. M., 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 291-304

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    34. Published

      Lipid-based colloidal carriers for targeted siRNA delivery

      Colombo, S. & Foged, Camilla, 1 Nov 2012, In: Therapeutic Delivery. 3, 11, p. 1245-1247 3 p.

      Research output: Contribution to journal › Review › Research › peer-review

    35. Published

      Lipid shell-enveloped polymeric nanoparticles with high integrity of lipid shells improve mucus penetration and interaction with cystic fibrosis-related bacterial biofilms

      Wan, F., Nylander, T., Klodzinska, S. N., Foged, Camilla, Yang, Mingshi, Baldursdottir, S. G. & Nielsen, Hanne Mørck, 23 Feb 2018, In: A C S Applied Materials and Interfaces. 10, 13, p. 10678–10687

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Lipid nanoparticles for local delivery of mRNA to the respiratory tract: Effect of PEG-lipid content and administration route

      Ongun, Melike, Lokras, Abhijeet, Baghel, Saahil Sandeep, Shi, Zhenning, Schmidt, S. T., Franzyk, Henrik, Rades, Thomas, Sebastiani, Federica, Thakur, A. & Foged, Camilla, 2024, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 198, 10 p., 114266.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids

      Ongun, Melike, Lokras, Abhijeet, Foged, Camilla & Thakur, A., 2022, Messenger RNA Therapeutics. Springer, p. 237-255 (RNA Technologies, Vol. 13).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    38. Published

      Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors

      Herrera-Barrera, M., Gautam, M., Lokras, Abhijeet, Vlasova, K., Foged, Camilla & Sahay, G., 2023, In: The AAPS Journal. 25, 4, 10 p., 65.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      License to kill: formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems

      Foged, Camilla, Hansen, J. & Agger, E. M., 2012, In: European Journal of Pharmaceutical Sciences. 45, 4, p. 482-491

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

      Xu, Y., Harinck, L., Lokras, Abhijeet, Gerde, P., Selg, E., Sjöberg, C., Franzyk, Henrik, Thakur, A. & Foged, Camilla, 2022, In: International Journal of Pharmaceutics. 621, 14 p., 121758.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Kan nanopartikler bruges i behandlingen af hudsygdomme?

      Jensen, L. B., Knudsen, N. Ø., Foged, Camilla & Nielsen, Hanne Mørck, 2010, In: Lægemiddelforskning. 2010, p. 10-12

      Research output: Contribution to journal › Journal article › Communication

    42. Published

      Intrapulmonary (i.pulmon.) Pull Immunization With the Tuberculosis Subunit Vaccine Candidate H56/CAF01 After Intramuscular (i.m.) Priming Elicits a Distinct Innate Myeloid Response and Activation of Antigen-Presenting Cells Than i.m. or i.pulmon. Prime Immunization Alone

      Thakur, A., Pinto, F. E., Hansen, Harald S., Andersen, Peter, Christensen, D., Janfelt, Christian & Foged, Camilla, 2020, In: Frontiers in Immunology. 11, p. 803

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

      Ragelle, H., Colombo, S., Pourcelle, V., Vanvarenberg, K., Vandermeulen, G., Bouzin, C., Marchand-Brynaert, J., Feron, O., Foged, Camilla & Préat, V., 10 Aug 2015, In: Journal of Controlled Release. 211, p. 1-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

      Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In: Langmuir. 28, 11, p. 5167-5175

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition

      Foged, Camilla, Arigita, C., Sundblad, A., Jiskoot, W., Storm, G. & Frøkjær, Sven, 2004, In: Vaccine. 22, 15-16, p. 1903-13 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Insights into the mechanisms of interaction between inhalable lipid-polymer hybrid nanoparticles and pulmonary surfactant

      Xu, Y., Parra-Ortiz, E., Wan, F., Cañadas, O., Garcia-Alvarez, B., Thakur, A., Franzyk, Henrik, Pérez-Gil, J., Malmsten, Martin & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 511-525

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Insight into Nanoscale Network of Spray-dried Polymeric Particles: Role of Polymer Molecular Conformation

      Wan, F., Larsen, F. H., Nunes Bordallo, Heloisa, Foged, Camilla, Rantanen, Jukka & Yang, Mingshi, 2018, In: A C S Applied Materials and Interfaces. 10, 43, p. 36686-36692

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Innovativt nanopartikeldesign bag skræddersyede vacciner

      Nordly, P. J., Agger, E. M., Nielsen, Hanne Mørck & Foged, Camilla, 2009, In: Lægemiddelforskning. p. 19-21

      Research output: Contribution to journal › Journal article › Research

    49. Published

      Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects

      Xu, You, Thakur, A., Zhang, Y. & Foged, Camilla, 2021, In: Pharmaceutics. 13, 2, 35 p., 77.

      Research output: Contribution to journal › Review › Research › peer-review

    50. Published

      Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying

      Agnoletti, M., Bohr, A., Thanki, K., Wan, F., Zeng, X., Bøtker, Johan Peter, Yang, Mingshi & Foged, Camilla, Nov 2017, In: European Journal of Pharmaceutics and Biopharmaceutics. 120, p. 9-21

      Research output: Contribution to journal › Journal article › Research › peer-review

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