Lasse Saaby

Lasse Saaby

Affiliated Associate Professor, Guest Researcher

Member of:

    ORCID: 0000-0003-4271-8304

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    1. Published

      iP-gp , a novel cell line with tight barrier function and expression of human P-glycoprotein (ABCB1) for drug screening

      Larsen, Birger Brodin, Ozgür, Burak & Saaby, Lasse, 23 May 2017.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    2. Published

      Ubiquitous plant compounds disturb cell-based assays

      Saaby, Lasse & Jäger, A. K., 1 Sep 2011, In: Journal of Ethnopharmacology. 137, 1, p. 942-943

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    3. Published

      Triterpene Acids from Rose Hip Powder Inhibit Self-antigen- and LPS-induced Cytokine Production and CD4(+) T-cell Proliferation in Human Mononuclear Cell Cultures

      Saaby, Lasse & Nielsen, Claus Henrik, Aug 2012, In: Phytotherapy Research. 26, 8, p. 1142-1147 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The putative proton-coupled organic cation antiporter is involved in uptake of triptans into human brain capillary endothelial cells

      Svane, Nana Isabella, Pedersen, Alberte Bay Villekjær, Rodenberg, A., Ozgür, Burak, Saaby, Lasse, Bundgaard, C., Kristensen, Mie, Tfelt-Hansen, P. & Larsen, Birger Brodin, 2024, In: Fluids and Barriers of the CNS. 21, 19 p., 39.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The putative P-gp inhibitor telmisartan does not affect the transcellular permeability and cellular uptake of the calcium channel antagonist verapamil in the P-glycoprotein expressing cell line MDCK II MDR1

      Saaby, Lasse, Tfelt-Hansen, P. & Larsen, Birger Brodin, 11 Jun 2015, In: Pharmacology Research & Perspectives. 3, 4, p. 1-9 9 p., e00151.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The iP-gp cell model is an improved tool for predicting the in vivo relevance of P-gp mediated efflux at the blood-brain barrier

      Ozgür, Burak, Saaby, Lasse, Eneberg, E., Langthaler, K., Jacobsen, A., Janfelt, Christian, Badolo, L., Montanari, D. & Larsen, Birger Brodin, 22 Jun 2018.

      Research output: Contribution to conference › Poster › Research › peer-review

    7. Published

      The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

      Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, Lasse, Larsen, Birger Brodin, Rump, S., Weigt, H., Brünner, N. & Stenvang, Jan, 4 Mar 2020, In: Cells. 9, 3, 22 p., 613.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      THE POSSIBLE EFFECT OF TELMISARTAN ON THE BLOOD-BRAIN BARRIER TRANSPORT OF VERAPAMIL.

      Saaby, Lasse, Tfelt-Hansen, P. & Larsen, Birger Brodin, 18 Sep 2014. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    9. Published

      Survival of Lactobacillus acidophilus NCFM® and Bifidobacterium lactis HN019 encapsulated in chocolate during in vitro simulated passage of the upper gastrointestinal tract

      Klindt-Toldam, S., Larsen, S. K., Saaby, Lasse, Olsen, L. R., Svenstrup, G., Mullertz, Anette , Knoechel, Susanne, Heimdal, H., Nielsen, Dennis Sandris & Zielińska, D., 2016, In: Lebensmittel - Wissenschaft und Technologie. 74, p. 404-410 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice

      Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, K., Eneberg, E., Jacobsen, A., Badolo, L., Montanari, D. & Larsen, Birger Brodin, 2021, In: European Journal of Pharmaceutics and Biopharmaceutics. 169, p. 211-219

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 4863000