Toxicology and Drug Metabolism

  1. 2022
  2. Published

    Isolation and toxicity evaluation of feruloyl ester and other triterpenoids from Synadenium glaucescens Pax

    Rwegoshora, F., Mabiki, F., Machumi, F., Chacha, M., Styrishave, Bjarne & Cornett, Claus, 2022, In: The Journal of Phytopharmacology. 11, 5, p. 347-352

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    LC-MS/MS Method for Determination of Non-opioid Analgesics Adulterants in Herbal Medicines

    Mpanyakavili, A. L., Mwankuna, C. J., Mabiki, F. P. & Styrishave, Bjarne, 2022, In: Chemistry Africa. 5, p. 2149–2162

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Mass spectrometry imaging in drug distribution and drug metabolism studies: Principles, applications and perspectives

    Granborg, J. R., Handler, A. M. & Janfelt, Christian, 2022, In: Trends in Analytical Chemistry. 146, 13 p., 116482.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Mass spectrometry imaging of oligosaccharides following in situ enzymatic treatment of maize kernels

    Granborg, J. R., Kaasgaard, S. G. & Janfelt, Christian, 2022, In: Carbohydrate Polymers. 275, 10 p., 118693.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Nicotinamide and phytochemicals phloroglucinol and syringic acid delay uvr-induced squamous cell carcinoma onset in hairless mice

    Pihl, Celina, Andersen, F., Bjerring, P., Hædersdal, Merete & Lerche, Catharina Margrethe, 2022, In: Anticancer Research. 42, 4, p. 2207-2207

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  7. Published

    Quantification of Urinary Thymidine Dimers in Volunteers After Ultraviolet Radiation Using a New UPLC-MS/MS-based Method

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 10, p. 5069-5076

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Quantifying urinary thymine dimers based on LC-MS/MS

    Lerche, Catharina Margrethe, Philipsen, P. A., Hermansson, S., Heydenreich, J. & Wulf, H. C., 2022, In: Anticancer Research. 42, 4, p. 2204-2204 22.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration

    Traberg, A., Pinto, F. E., Hansen, Anders Christian Nørgaard, Hædersdal, Merete, Lerche, Catharina Margrethe & Janfelt, Christian, 2022, In: Pharmaceuticals. 15, 12, 15 p., 1583.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Reservoir of Antibiotic Residues and Resistant Coagulase Negative Staphylococci in a Healthy Population in the Greater Accra Region, Ghana

    Bekoe, S. O., Hane-Weijman, S., Trads, S. L., Orman, E., Opintan, J., Hansen, M., Frimodt-Møller, N. & Styrishave, Bjarne, 2022, In: Antibiotics. 11, 1, 12 p., 119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Smooth muscle ATP-sensitive potassium channels mediate migraine-relevant hypersensitivity in mouse models

    Christensen, S. L., Rasmussen, Rikke Holm, Cour, S. L., Ernstsen, C., Hansen, Thomas Folkmann, Kogelman, L. J. A., Lauritzen, S. P., Guzaite, G., Styrishave, Bjarne, Janfelt, Christian, Christensen, Søren Tvorup, Aziz, Q., Tinker, A., Jansen-Olesen, I., Olesen, Jes & Kristensen, D. M., 2022, In: Cephalalgia. 42, 2, p. 93-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The Acute and Chronic Effects of Acetazolamide and Topiramate on Intracranial Pressure and CSF Secretion

    Westgate, C., Kamp-Jensen, C., Israelsen, I., Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Jensen, C., Styrishave, Bjarne, MacAulay, Nanna, Jensen, Rasmus Herlo Beenfeldt & Eftekhari, S., 2022, In: Journal of Headache and Pain. 23, Suppl. 1, 1 p., P218.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Tissue distribution and metabolic profiling of cyclosporine (CsA) in mouse and rat investigated by DESI and MALDI mass spectrometry imaging (MSI) of whole-body and single organ cryo-sections

    Holm, N. B., Deryabina, M., Knudsen, C. B. & Janfelt, Christian, 2022, In: Analytical and Bioanalytical Chemistry. 414, p. 7167–7177

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Topical Brimonidine Delays Ultraviolet Radiation-Induced Squamous Cell Carcinoma in Hairless Mice

    Pinto, F. E., Olsen, P., Glud, M., Wulf, H. C. & Lerche, Catharina Margrethe, 2022, In: Photochemistry and Photobiology. 98, 6, p. 1390-1394

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2021
  16. Published

    A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy

    Wulf, H. C., Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Lerche, Catharina Margrethe, May 2021, In: Pharmaceuticals. 14, 5, 11 p., 433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging

    Hendel, K., Hansen, Anders Christian Nørgaard, Bik, L., Bagger, C., van Doorn, M. B. A., Janfelt, Christian, Olesen, U. H., Hædersdal, Merete & Lerche, Catharina Margrethe, 1 Jan 2021, In: Drug Delivery. 28, 1, p. 1141-1149 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A Comparison of Human and Porcine Skin in Laser-Assisted Drug Delivery of Chemotherapeutics

    Rosenberg, L. K., Bagger, C., Janfelt, Christian, Hædersdal, Merete, Olesen, U. H. & Lerche, Catharina Margrethe, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 162-170 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A quantitative method for the selective 5-HT2A agonist 25CN-NBOH in rat plasma and brain

    Breusova, K., Ernstsen, K. G., Palner, M., Linnet, Kristian, Kristensen, Jesper Langgaard & Kretschmann, A. C., 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Acetaminophen metabolism revisited using non-targeted analyses: Implications for human biomonitoring

    David, A., Chaker, J., Leger, T., Al-Salhi, R., Dalgaard, M. D., Styrishave, Bjarne, Bury, D., Koch, H. M., Jegou, B. & Kristensen, D. M., 2021, In: Environment International. 149, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Anti-pd-1 therapy with adjuvant ablative fractional laser improves anti-tumor response in basal cell carcinomas

    Olesen, U. H., Wiinberg, M., Lerche, Catharina Margrethe, Jæhger, D. E., Andresen, T. L. & Hædersdal, Merete, 2021, In: Cancers. 13, 24, 14 p., 6326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Baseline Hepcidin Does Not Predict the Response to Iron Therapy in Pregnant Women with Iron Deficiency

    Hansen, R., Kurtzhals, Jørgen, Styrishave, Bjarne & Bischof, Charlotte Holm, 2021, In: Blood. 138, Suppl 1, 3076.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  23. Published

    Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging

    Handler, A. M., Eirefelt, S., Lambert, M., Johansson, F., Hollesen Schefe, L., Knudsen, N. Ø., Bodenlenz, M., Birngruber, T., Sinner, F., Eriksson, A. H., Pedersen, G. P., Janfelt, Christian & Troensegaard Nielsen, K., 2021, In: Molecular Pharmaceutics. 18, 8, p. 3063-3072

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

    Jacobsen, S. C., Speth, N. R., Xiong, M., Herth, Matthias Manfred, Kristensen, Jesper Langgaard, Palner, M. & Janfelt, Christian, 2021, In: Molecular Imaging and Biology. 23, p. 676–685

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Efficacy and Safety of Laser‐Assisted Combination Chemotherapy: An Explorative Imaging‐Guided Treatment With 5‐Fluorouracil and Cisplatin for Basal Cell Carcinoma

    Wenande, E., Hendel, K., Mogensen, Mette, Bagger, C., Mårtensson, Nina Løth, Persson, Daniel Pergament, Lerche, C. M., Husted, Søren, Janfelt, Christian, Togsverd‐bo, K., Anderson, R. R. & Hædersdal, Merete, 2021, In: Lasers in Surgery and Medicine. 53, 1, p. 119-128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Few X-ray and PUVA treatments accelerate photocarcinogenesis in hairless mice

    Lerche, Catharina Margrethe, Al-Chaer, R. N., Glud, M., Philipsen, P. A. & Wulf, H. C., 2021, In: Photochemical and Photobiological Sciences. 20, 10, p. 1299-1307

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?

    Johannsen, Malene Louise, Munkboel, C. H., Jørgensen, Flemming Steen & Styrishave, Bjarne, 2021, In: Journal of Steroid Biochemistry and Molecular Biology. 205, 10 p., 105765.

    Research output: Contribution to journalJournal articleResearchpeer-review