Physiological Pharmaceutics

Read more
101 - 150 out of 179Page size: 50
  1. 2020
  2. Published

    Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing

    Eleftheriadis, G. K., Monou, P. K., Bouropoulos, N., Bøtker, Johan Peter, Rantanen, Jukka, Jacobsen, Jette, Vizirianakis, I. S. & Fatouros, D. G., 2020, In: Journal of Pharmaceutical Sciences. 109, 9, p. 2757-2766

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy

    Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro

    Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impact of gastrointestinal physiology on drug absorption in special populations – An UNGAP review

    Stillhart, C., Vucicevic, K., Augustijns, P., Basit, A. W., Batchelor, H., Flanagan, T. R., Gesquiere, I., Greupink, R., Keszthelyi, D., Koskinen, M., Madla, C. M., Matthys, C., Miljus, G., Mooij, M. G., Parrott, N., Ungell, A. -., de Wildt, S. N., Orlu, M., Klein, S. & Mullertz, Anette , 2020, In: European Journal of Pharmaceutical Sciences. 147, 28 p., 105280.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Improving the drug load and in vitro performance of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) using polymeric precipitation inhibitors

    Bannow, J., Yorulmaz, Y., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 575, 1188960.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    In Vitro Evaluation of Self-Nano-Emulsifying Drug Delivery Systems (SNEDDS) Containing Room Temperature Ionic Liquids (RTILs) for the Oral Delivery of Amphotericin B

    Kontogiannidou, E., Meikopoulos, T., Gika, H., Panteris, E., Vizirianakis, I. S., Mullertz, Anette & Fatouros, D. G., 2020, In: Pharmaceutics. 12, 8, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products [incl, correction]

    Selen, A., Mullertz, Anette , Kesisoglou, F., Ho, R. J. Y., Cook, J. A., Dickinson, P. A. & Flanagan, T., 2020, In: AAPS Journal. 22, 5, 20 p., 97.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro

    He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Single particles as resonators for thermomechanical analysis

    Okeyo, P. O., Larsen, P. E., Kissi, E. O., Ajalloueian, F., Rades, Thomas, Rantanen, Jukka & Boisen, A., 2020, In: Nature Communications. 11, 1, 11 p., 1235.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Temperature-Modulated Micromechanical Thermal Analysis with Microstring Resonators Detects Multiple Coherent Features of Small Molecule Glass Transition

    Karl, M., Thamdrup, L. H. E., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 2020, In: Sensors. 20, 4, 14 p., 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems

    Tran, T., Bonlokke, P., Rodriguez-Rodriguez, C., Nosrati, Z., Esquinas, P. L., Borkar, N., Plum, J., Strindberg, S., Karagiozov, S., Rades, Thomas, Mullertz, Anette , Saatchi, K. & Hafeli, U. O., 2020, In: Journal of Controlled Release. 317, p. 375-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Waterborne Electrospinning of α-Lactalbumin Generates Tunable and Biocompatible Nanofibers for Drug Delivery

    Stie, Mai Bay, Corezzi, M., Juncos Bombin, A. D., Ajalloueian, F., Attrill, E., Pagliara, S., Jacobsen, Jette, Chronakis, I. S., Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: ACS Applied Nano Materials. 3, 2, p. 1910–1921

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2019
  15. Published

    Determining Thermal Conductivity of Small Molecule Amorphous Drugs with Modulated Differential Scanning Calorimetry and Vacuum Molding Sample Preparation

    Karl, M., Rantanen, Jukka & Rades, Thomas, 6 Dec 2019, In: Pharmaceutics. 11, 12, 7 p., 670.

    Research output: Contribution to journal › Journal article › Communication

  16. Published

    Fast and quantitative 2D and 3D orientation mapping using Raman microscopy

    Ilchenko, O., Pilgun, Y., Kutsyk, A., Slipets, R., Bachmann, F., Todeschini, M., Okeyo, P. O., Friis Poulsen, H. & Boisen, A., 5 Dec 2019, In: Nature Communications. 10, 9 p., 5555.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Investigation of Mucoadhesion and Degradation of PCL and PLGA Microcontainers for Oral Drug Delivery

    Abid, Z., Dalskov Mosgaard, M., Manfroni, G., Singh Petersen, R., Hagner Nielsen, L., Mullertz, Anette , Boisen, A. & Sylvest Keller, S., Nov 2019, In: Polymers. 11, 10 p., 1828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

    Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers

    Stie, Mai Bay, Jones, M., Sørensen, H. O., Jacobsen, Jette, Chronakis, I. S. & Nielsen, Hanne Mørck, 1 Jul 2019, In: Carbohydrate Polymers. 215, p. 253-262

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Quantification of Inkjet-Printed Pharmaceuticals on Porous Substrates Using Raman Spectroscopy and Near-Infrared Spectroscopy

    Edinger, M., Iftimi, L., Markl, D., Al-Sharabi, M., Bar-Shalom, Daniel, Rantanen, Jukka & Genina, Natalja, Jul 2019, In: AAPS PharmSciTech. 20, 5, 10 p., 207.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    In vitro digestion models to evaluate lipid based drug delivery systems; present status and current trends

    Berthelsen, R., Klitgaard, Mette, Rades, Thomas & Mullertz, Anette , 29 Jun 2019, In: Advanced Drug Delivery Reviews. 142, p. 35-49 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Biorelevant intrinsic dissolution profiling in early drug development: Fundamental, methodological, and industrial aspects

    Bergstrom, C. A. S., Box, K., Holm, R., Matthews, W., McAllister, M., Mullertz, Anette , Rades, Thomas, Schaefer, K. J. & Teleki, A., Jun 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 101-114

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Imaging of dehydration in particulate matter using Raman line-focus microscopy

    Okeyo, P. O., Ilchenko, O., Slipets, R., Larsen, P. E., Boisen, A., Rades, Thomas & Rantanen, Jukka, 17 May 2019, In: Scientific Reports. 9, 11 p., 7525.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Mimicking regional and fasted/fed state conditions in the intestine with the mucus-PVPA in vitro model: The impact of pH and simulated intestinal fluids on drug permeability

    Falavigna, M., Klitgaard, Mette, Steene, E. & Flaten, G. E., 30 Apr 2019, In: European Journal of Pharmaceutical Sciences. 132, p. 44-54 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Digestive Enzyme Corona Formed in the Gastrointestinal Tract and Its Impact on Epithelial Cell Uptake of Nanoparticles

    Peng, Q., Liu, J., Zhang, T., Zhang, T., Zhang, C. & Mu, Huiling, 8 Apr 2019, In: Biomacromolecules. 20, 4, p. 1789-1797 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    SEDDS for intestinal absorption of insulin: Application of Caco-2 and Caco-2/HT29 co-culture monolayers and intra-jejunal instillation in rats

    Liu, J., Werner, U., Funke, M., Besenius, M., Saaby, Lasse, Fano, M., Mu, Huiling & Mullertz, Anette , 5 Apr 2019, In: International Journal of Pharmaceutics. 560, p. 377-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Edible solid foams as porous substrates for inkjet-printable pharmaceuticals

    Iftimi, L., Edinger, M., Bar-Shalom, Daniel, Rantanen, Jukka & Genina, Natalja, Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 38-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

    Butler, J., Hens, B., Vertzoni, M., Brouwers, J., Berben, P., Dressman, J., Andreas, C. J., Schaefer, K. J., Mann, J., McAllister, M., Jamei, M., Kostewicz, E., Kesisoglou, F., Langguth, P., Minekus, M., Mullertz, A., Schilderink, R., Koziolek, M., Jedamzik, P., Weitschies, W. & 2 others, Reppas, C. & Augustijns, P., Mar 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 136, p. 70-83

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery

    Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Exploring the utility of the Chasing-rinciple: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

    Jorgensen, S. D. S., Rades, Thomas, Mu, Huiling, Graeser, K. & Mullertz, Anette , Jan 2019, In: Acta Pharmaceutica Sinica B. 9, 1, p. 194-201

    Research output: Contribution to journal › Letter › Research › peer-review

  31. Published

    A Bayesian Generative Model with Gaussian Process Priors for Thermomechanical Analysis of Micro-Resonators

    Vording, M. F., Okeyo, P. O., Guillamon, J. J. R., Larsen, P. E., Schmidt, M. N. & Alstrom, T. S., 2019, 2019 IEEE 29th International Workshop on Machine Learning for Signal Processing, MLSP 2019. IEEE, 8918876. (IEEE International Workshop on Machine Learning for Signal Processing, MLSP, Vol. 2019-October).

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  32. Published

    Biodegradable microcontainers-towards real life applications of microfabricated systems for oral drug delivery

    Abid, Z., Strindberg, S., Javed, M. M., Mazzoni, C., Vaut, L., Nielsen, L. H., Gundlach, C., Petersen, R. S., Mullertz, Anette , Boisen, A. & Keller, S. S., 2019, In: Lab on a Chip. 19, 17, p. 2905-2914 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats

    Christfort, J. F., Strindberg, S., Plum, J., Hall-Andersen, J., Janfelt, Christian, Nielsen, L. H. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 307-314 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Ex vivo intestinal perfusion model for investigating mucoadhesion of microcontainers

    Dalskov Mosgaard, M., Strindberg, S., Abid, Z., Singh Petersen, R., Højlund Eklund Thamdrup, L., Joukainen Andersen, A., Sylvest Keller, S., Mullertz, Anette , Hagner Nielsen, L. & Boisen, A., 2019, In: International Journal of Pharmaceutics. 570, 118658.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Fenofibrate oral absorption from SNEDDS and super-SNEDDS is not significantly affected by lipase inhibition in rats

    Michaelsen, M. H., Siqueira Jørgensen, S. D., Abdi, I. M., Wasan, K. M., Rades, Thomas & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 258-264 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Hvordan udvikler vi bedre medicin til børn?

    Berthelsen, R., 2019, Videnskab.dk, ForskerZonen.

    Research output: Other contribution › Net publication - Internet publication › Communication

  37. Published

    In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development

    Zane, P., Gieschen, H., Kersten, E., Mathias, N., Ollier, C., Johansson, P., Van den Bergh, A., Van Hemelryck, S., Reichel, A., Rotgeri, A., Schäfer, K., Mullertz, Anette & Langguth, P., 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 222-231 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Microcontainers for oral insulin delivery - in vitro studies of permeation enhancement

    Rune Jørgensen, J., Leth Jepsen, M., Hagner Nielsen, L., Dufva, M., Nielsen, Hanne Mørck, Rades, Thomas, Boisen, A. & Mullertz, Anette , 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 143, p. 98-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Polymeric Lids for Microcontainers for Oral Protein Delivery

    Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Self-emulsifying drug delivery systems (SEDDS) – The splendid comeback of an old technology

    Bernkop-Schnürch, A., Mullertz, Anette & Rades, Thomas, 2019, In: Advanced Drug Delivery Reviews. 142, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  41. Published

    Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

    Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Mullertz, Anette , Bauer-Brandl, A. & Jannin, V., 2019, In: European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2018
  43. Published

    Analytical aspects of printed oral dosage forms

    Edinger, M., Jacobsen, Jette, Bar-Shalom, Daniel, Rantanen, Jukka & Genina, Natalja, 20 Dec 2018, In: International Journal of Pharmaceutics. 553, 1-2, p. 97-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Ultra Sensitive Micro String Resonators for Solid State Thermomechanical Analysis of Small and Large Molecules

    Karl, M., Larsen, P. E., Rangacharya, V., Hwu, E. T., Rantanen, Jukka, Boisen, A. & Rades, Thomas, 19 Dec 2018, In: Journal of the American Chemical Society. 140, 50, p. 17522-17531

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Buccal delivery of small molecules - Impact of levulinic acid, oleic acid, sodium dodecyl sulfate and hypotonicity on ex vivo permeability and spatial distribution in mucosa

    Hansen, S. E., Marxen, E., Janfelt, Christian & Jacobsen, Jette, Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 250-257

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Challenges and trends in apomorphine drug delivery systems for the treatment of Parkinson's disease

    Borkar, N., Mu, Huiling & Holm, R., 1 Nov 2018, In: Asian Journal of Pharmaceutical Sciences. 13, 6, p. 507-517 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp)

    Khumpirapang, N., Chaichit, S., Jiranusornkul, S., Pikulkaew, S., Mullertz, Anette & Okonogi, S., 1 Nov 2018, In: Aquaculture. 496, p. 176-184

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles

    Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers

    Blaabjerg, L. I., Grohganz, Holger, Lindenberg, E., Löbmann, Korbinian, Mullertz, Anette & Rades, Thomas, 21 Sep 2018, In: Pharmaceutics. 10, 4, 14 p., 164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    A fast and novel internal calibration method for quantitative Raman measurements on aqueous solutions

    Duraipandian, S., Knopp, Matthias Manne, Pollard, M. R., Kerdoncuff, H., Petersen, J. C. & Mullertz, Anette , 7 Aug 2018, In: Analytical Methods. 10, 29, p. 3589-3593

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Solid lipid nanocarriers in drug delivery: characterization and design

    Mu, Huiling & Holm, R., Aug 2018, In: Expert Opinion on Drug Delivery. 15, 8, p. 771-785 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  52. Published

    Application of a Salt Coformer in a Co-Amorphous Drug System Dramatically Enhances the Glass Transition Temperature: A Case Study of the Ternary System Carbamazepine, Citric Acid, and L-Arginine

    Ueda, H., Wu, W., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette & Rades, Thomas, May 2018, In: Molecular Pharmaceutics. 15, 5, p. 2036-2044

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Assessment of the analgesic dipyrone as a possible (anti) androgenic endocrine disruptor

    Passoni, M. T., Kristensen, M. N., Morais, R. N., Woitkowiak, C., Boareto, A. C., da Silva Amaral, B. A., Grechi, N., Dalsenter, P. R., Munkboel, C. H., Styrishave, Bjarne, Kristensen, D. M., Gomes, C., van Ravenzwaay, B. & Martino-Andrade, A. J., 15 Mar 2018, In: Toxicology Letters. 285, p. 139-147

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 4 Next