Pharmaceutical Physical and Analytical Chemistry

  1. 2021
  2. Published

    Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops

    Mullertz, O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihaly, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J., Utheim, T., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: BMJ Open Ophthalmology. 6, 1, 7 p., 000892.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In situ monitoring of the formation of lipidic non-lamellar liquid crystalline depot formulations in synovial fluid

    Yaghmur, Anan, Rappolt, M., Jonassen, A. L. U., Schmitt, M. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 582, p. 773-781 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Multi-material 3D printing of programmable and stretchable oromucosal patches for delivery of saquinavir

    He, S., Radeke, C., Jacobsen, Jette, Lind, J. U. & Mu, Huiling, 2021, In: International Journal of Pharmaceutics. 610, 9 p., 121236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pulmonary Delivery of Anticancer Drugs via Lipid-Based Nanocarriers for the Treatment of Lung Cancer: An Update

    Abdulbaqi, I. M., Assi, R. A., Yaghmur, Anan, Darwis, Y., Mohtar, N., Parumasivam, T., Saqallah, F. G. & Wahab, H. A., 2021, In: Pharmaceuticals. 14, 8, 39 p., 725.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species

    Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media

    Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Tid til læring i laboratoriet: farmaceutstuderendes opfattelse af tiden i laboratorieundervisningen

    Finne, Laura Teinholt, Gammelgaard, Bente & Christiansen, Frederik Voetmann , 2021, In: Dansk Universitetspædagogisk Tidsskrift. 16, 30, p. 43-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution

    Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Recent advances in drug delivery applications of cubosomes, hexosomes, and solid lipid nanoparticles

    Yaghmur, Anan & Mu, Huiling, Apr 2021, In: Acta Pharmaceutica Sinica B (Online). 11, 4, p. 871-885 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

    Flouda, K., Gammelgaard, Bente, Davies, Michael J. & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2022
  13. Published

    In Vitro Characterization of a Threonine-Ligated Molybdenyl-Sulfide Cluster as a Putative Cyanide Poisoning Antidote: Intracellular Distribution, Effects on Organic Osmolyte Homeostasis, and Induction of Cell Death

    Gretarsdottir, J. M., Lambert, Ian Henry, Stürup, Stefan & Suman, S. G., 2022, In: ACS Pharmacology and Translational Science. 5, 10, p. 907–918

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis

    Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Cell medium-dependent dynamic modulation of size and structural transformations of binary phospholipid/ω-3 fatty acid liquid crystalline nano-self-assemblies: Implications in interpretation of cell uptake studies

    Bor, G., Salentinig, S., Şahin, E., Nur Ödevci, B., Roursgaard, Martin, Liccardo, L., Hamerlik, P., Moghimi, S. M. & Yaghmur, Anan, 2022, In: Journal of Colloid and Interface Science. 606, p. 464-479 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Danish university faculty perspectives on student learning outcomes in the teaching laboratories of a pharmaceutical sciences education

    Agustian, Hendra Y., Pedersen, M. I., Finne, Laura Teinholt, Jørgensen, Jonas Tarp, Nielsen, Jan Alexis & Gammelgaard, Bente, 2022, In: Journal of Chemical Education. 99, 11, p. 3633–3643

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Development of a multiparticulate drug delivery system for in situ amorphisation

    Holm, T. P., Kokott, M., Knopp, Matthias Manne, Boyd, Ben, Berthelsen, R., Quodbach, J. & Löbmann, Korbinian, 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 170-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Direct visualizing of paracetamol immediate release tablet disintegration in vivo and in vitro

    Fredholt, Freja, Di Meo, C., Sloth, S., Mullertz, Anette & Berthelsen, R., 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 180, p. 63-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    In vitro and ex vivo evaluation of bilayered effervescent microenvironmental pH modifying buccal films with saquinavir

    He, S., Nielsen, C. U., Mu, Huiling & Jacobsen, Jette, 2022, In: Journal of Drug Delivery Science and Technology. 78, 7 p., 103954.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro

    Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Investigation of diclofenac release and dynamic structural behavior of non-lamellar liquid crystal formulations during in situ formation by UV–Vis imaging and SAXS

    Mertz, Nina, Bock, Frederik, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 2022, In: International Journal of Pharmaceutics. 623, 121880.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Laboratory discourse through the lens of multidimensional learning

    Agustian, Hendra Y. & Gammelgaard, Bente, 2022. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  24. Published

    Laboratory work as an epistemic practice: Discursive characteristics of student learning in the pharmaceutical chemistry teaching laboratory

    Agustian, Hendra Y. & Gammelgaard, Bente, 2022. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  25. Published
  26. Published

    Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance

    Bock, Frederik, Bøtker, Johan Peter, Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2022, In: International Journal of Molecular Sciences. 23, 7, 18 p., 3599.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Microfluidic Nanomaterial Synthesis and In Situ SAXS, WAXS, or SANS Characterization: Manipulation of Size Characteristics and Online Elucidation of Dynamic Structural Transitions

    Yaghmur, Anan & Hamad, I., 2022, In: Molecules. 27, 14, 4602.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Nanometer- and angstrom-scale characteristics that modulate complement responses to nanoparticles

    Moghimi, S. M., Haroon, H. B., Yaghmur, Anan, Simberg, D. & Trohopoulos, P. N., 2022, In: Journal of Controlled Release. 351, p. 432-443

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    PEGylation of Phosphatidylglycerol/Docosahexaenoic Acid Hexosomes with d -α-Tocopheryl Succinate Poly(ethylene glycol)2000Induces Morphological Transformation into Vesicles with Prolonged Circulation Times

    Bor, G., Lin, J. H., Lin, K. Y., Chen, H. C., Prajnamitra, R. P., Salentinig, S., Hsieh, P. C. H., Moghimi, S. M. & Yaghmur, Anan, 2022, In: ACS applied materials & interfaces. 14, 43, p. 48449-48463

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Physico-chemical characterization of aspirated and simulated human gastric fluids to study their influence on the intrinsic dissolution rate of cinnarizine

    Pedersen, P. B., Berthelsen, R., Rades, Thomas, Jørgensen, S. A., Vilmann, Peter, Bar-Shalom, Daniel, Baldursdottir, S. & Mullertz, Anette , 2022, In: International Journal of Pharmaceutics. 622, 7 p., 121856.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis

    Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Supersaturated amorphous solid dispersions of celecoxib prepared in situ by microwave irradiation

    Holm, T. P., Knopp, Matthias Manne, Berthelsen, R. & Löbmann, Korbinian, 2022, In: International Journal of Pharmaceutics. 626, 8 p., 122115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The physicochemical properties of preserved and preservative-free latanoprost eye drops and their impact on human conjunctival goblet cells

    Müllertz, O. A. O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihály, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J. A., Utheim, T. P., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, S267

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    When the Lab Work Disappears: Students' Perception of Laboratory Teaching for Quality Learning

    Finne, Laura Teinholt, Gammelgaard, Bente & Christiansen, Frederik Voetmann , 2022, In: Journal of Chemical Education. 99, 4, p. 1766-1774 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2023
  36. Published

    Assessing acute colitis induced by dextran sulfate sodium in rats and its impact on gastrointestinal fluids

    Klitgaard, Mette, Kristensen, M. N., Venkatasubramanian, R., Guerra, Priscila Regina, Jacobsen, Jette, Berthelsen, R., Rades, Thomas & Mullertz, Anette , 2023, In: Drug Delivery and Translational Research. 13, p. 1484–1499

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform

    Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization

    Bock, Frederik, Hu, A., Cicale, V., Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Enculturation of pharmacy students into scientific practices: a closer look into affect and conation in the laboratory of pharmaceutical sciences

    Agustian, Hendra Y. & Gammelgaard, Bente, 2023. 4 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  40. Published

    Intravenous Infusion of High Dose Selenite in End-Stage Cancer Patients: Analysis of Systemic Exposure to Selenite and Seleno-Metabolites

    Breuer, O., Brodin, O., Razaghi, A., Brodin, D., Gammelgaard, Bente & Bjoernstedt, M., 2023, In: Biomedicines. 11, 2, 10 p., 295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Intrinsic and Dynamic Heterogeneity of Nonlamellar Lyotropic Liquid Crystalline Nanodispersions

    Yaghmur, Anan & Moghimi, S. M., 2023, In: ACS Nano. 17, 22, p. 22183–22195

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Lipid nanoparticles for targeted delivery of anticancer therapeutics: Recent advances in development of siRNA and lipoprotein-mimicking nanocarriers

    Yaghmur, Anan, Østergaard, Jesper & Mu, Huiling, 2023, In: Advanced Drug Delivery Reviews. 203, 10 p., 115136.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Microenvironmental pH Modification in Buccal/Sublingual Dosage Forms for Systemic Drug Delivery

    He, S. & Mu, Huiling, 2023, In: Pharmaceutics. 15, 2, 18 p., 637.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel

    Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Omega-3 fatty acid nanocarriers: Characterization and potential applications

    Yaghmur, Anan, Ghayas, Sana, Jan, Habibullah, Kalaycioglu, Gokce Dicle & Moghimi, S. M., 2023, In: Current Opinion in Colloid and Interface Science. 67, 13 p., 101728.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Perspectives on complement and phagocytic cell responses to nanoparticles: From fundamentals to adverse reactions

    Moghimi, S. M., Haroon, H. B., Yaghmur, Anan, Hunter, A. C., Papini, E., Farhangrazi, Z. S., Simberg, D. & Trohopoulos, P. N., 2023, In: Journal of Controlled Release. 356, p. 115-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Pharmacy students' conceptions of theory-practice relation in the analytical chemistry laboratory: a phenomenographic study

    Finne, Laura Teinholt, Gammelgaard, Bente & Christiansen, Frederik Voetmann , 2023, In: Chemistry Education Research and Practice. 24, 2, p. 428–436

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

    Wadhwa, A., Bobak, T. R., Bohrmann, L., Geczy, R., Sekar, S., Sathyanarayanan, G., Kutter, Jörg P., Franzyk, Henrik, Foged, Camilla, Saatchi, K. & Häfeli, U. O., 2023, In: OpenNano. 13, 12 p., 100180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Selenomethionine as alternative label to the fluorophore TAMRA when exploiting cell-penetrating peptides as blood-brain barrier shuttles to better mimic the physicochemical properties of the non-labelled peptides

    Ýr Þorgeirsdóttir, D., Hofman Andersen, J., Perch-Nielsen, M., Møller, L. H., Grønbæk-Thorsen, F., Kolberg, Hannah Grønbech, Gammelgaard, Bente & Kristensen, Mie, 2023, In: European Journal of Pharmaceutical Sciences. 183, 10 p., 106400.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Teacher Intentions vs Student Perception of Feedback on Laboratory Reports

    Jørgensen, Jonas Tarp, Gammelgaard, Bente & Christiansen, Frederik Voetmann , 2023, In: Journal of Chemical Education. 100, 10, p. 3764–3773

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published
  52. Published
  53. Published

    Determination of Trace Elements in Ibuprofen Drug Products Using Microwave-Assisted Acid Digestion and Inductively Coupled Plasma-Mass Spectrometry

    Holmfred, Else Skovgaard, Alrijjal, A., Chamberlain, C. P., Maher, K. & Stürup, Stefan, 1 Aug 2023, Social Science Research Network (SSRN), 22 p. (JPBA-D-23-01192).

    Research output: Working paperPreprint