CNS Drug Delivery and Barrier Modelling

  1. 2020
  2. E-pub ahead of print

    Brain endothelial cells metabolize glutamate via glutamate dehydrogenase to replenish TCA-intermediates and produce ATP under hypoglycemic conditions

    Hinca, S. B., Salcedo, C., Wagner, A., Goldeman, C., Sadat, E., Aibar, M. M. D., Maechler, P., Brodin, Birger, Aldana, B. I. & Helms, H. C. C., 7 Oct 2020, In : Journal of Neurochemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Human induced pluripotent stem cells (BIONi010-C) generate tight cell monolayers with blood-brain barrier traits and functional expression of large neutral amino acid transporter 1 (SLC7A5)

    Goldeman, C., Andersen, M., Al-Robai, A., Buchholtz, T., Svane, N., Ozgür, Burak, Holst, Birgitte, Shusta, E., Hall, Vanessa Jane, Saaby, L., Hyttel, Poul & Brodin, Birger, 1 Oct 2020, In : European Journal of Pharmaceutical Sciences. p. 105577

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    IPEC-J2 rMdr1a, a New Cell Line with Functional Expression of Rat P-glycoprotein Encoded by Rat Mdr1a for Drug Screening Purposes

    Saaby, L., Trasborg, J., Rasmussen, M. A., Holst, B. & Brodin, Birger, 17 Jul 2020, In : Pharmaceutics. 12, 7, 17 p., 673.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Culture of brain capillary pericytes for cytosolic calcium measurements and calcium imaging studies

    Hørlyck, S., Helms, H. C. C. & Brodin, Birger, May 2020, In : Journal of Visualized Experiments. 2020, 159, p. 1-9 9 p., e61253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells

    Goldeman, C., Ozgür, Burak & Brodin, Birger, 22 Apr 2020, In : Fluids and Barriers of the CNS. 17, 32, 12 p., 32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP

    Ambjørner, S. E. B., Wiese, M., Köhler, S. C., Svindt, J., Lund, X. L., Gajhede, Michael, Saaby, L., Brodin, Birger, Rump, S., Weigt, H., Brünner, Nils & Stenvang, Jan, 4 Mar 2020, In : Cells. 9, 3, 22 p., 613.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Accepted/In press

    Tight junctions in the blood–brain barrier promote edema formation and infarct size in stroke – Ambivalent effects of sealing proteins

    Winkler, L., Blasig, R., Breitkreuz-Korff, O., Berndt, P., Dithmer, S., Helms, H. C., Puchkov, D., Devraj, K., Kaya, M., Qin, Z., Liebner, S., Wolburg, H., Andjelkovic, A. V., Rex, A., Blasig, I. E. & Haseloff, R. F., 1 Jan 2020, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A novel derivative of thioridazine shows low toxicity and efficient activity against gram‐positive pathogens

    Jørgensen, N. S., Saaby, L., Andersson, A. M., Kromann, Sofie, Sheikhsamani, E., Permin, A., Ronco, T., Svenningsen, S. W., Christensen, Jørn Bolstad & Olsen, Rikke Heidemann, 2020, In : Antibiotics. 9, 6, 11 p., 327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana Garcia, Blanca Irene, Lauritzen, Martin & Brodin, Birger, 2020, In : Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2019
  12. Published

    Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures

    Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Brodin, Birger, 2019, In : PLoS ONE. 14, 8, 20 p., e0221103.

    Research output: Contribution to journalJournal articleResearchpeer-review

Previous 1 2 3 Next