- Published
Characterization of an iPSC-based barrier model for blood-brain barrier investigations using the SBAD0201 stem cell line
Ozgür, Burak, Puris, E., Brachner, A., Appelt-Menzel, A., Oerter, S., Balzer, V., Holst, M. R., Christiansen, R. F., Hyldig, K., Buckley, S. T., Kristensen, Mie, Auriola, S., Jensen, A., Fricker, G., Nielsen, M. S., Neuhaus, W. & Larsen, Birger Brodin, 2023, In: Fluids and Barriers of the CNS. 20, 1, 15 p., 96.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the IPEC-J2 MDR1 (iP-gp) cell line as a tool for identification of P-gp substrates
Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: European Journal of Pharmaceutical Sciences. 112, p. 112-121 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical and Regulatory Aspects of Companion Diagnostic Development in Oncology
Jorgensen, J. T. & Hersom, M., Jun 2018, In: Clinical Pharmacology & Therapeutics. 103, 6, p. 999-1008Research output: Contribution to journal › Review › Research › peer-review
- Published
Companion and Complementary Diagnostics-Focus on PD-L1 Expression Assays for PD-1/PD-L1 Checkpoint Inhibitors in Non-Small Cell Lung Cancer
Hersom, M. & Jorgensen, J. T., Feb 2018, In: Therapeutic Drug Monitoring. 40, 1, p. 9-16Research output: Contribution to journal › Review › Research › peer-review
- Published
Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation
Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Considerations regarding use of solvents in in vitro cell based assays
Timm, M., Saaby, Lasse, Moesby, L. & Hansen, E. W., Oct 2013, In: Cytotechnology. 65, 5, p. 887-894 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Culture of brain capillary pericytes for cytosolic calcium measurements and calcium imaging studies
Hørlyck, S., Helms, H. C. C. & Larsen, Birger Brodin, May 2020, In: Journal of Visualized Experiments. 159, p. 1-9 9 p., e61253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells
Goldeman, C., Ozgür, Burak & Larsen, Birger Brodin, 22 Apr 2020, In: Fluids and Barriers of the CNS. 17, 32, 12 p., 32.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates
Ozgür, Burak, Saaby, Lasse, Langthaler, K. & Larsen, Birger Brodin, 2018, In: Data in Brief. 16, p. 655-659 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures
Tornabene, E., Helms, H. C. C., Pedersen, Stine Helene Falsig & Larsen, Birger Brodin, 2019, In: PLoS ONE. 14, 8, 20 p., e0221103.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
201
downloads
Data demonstrating the challenges of determining the kinetic parameters of P-gp mediated transport of low-water soluble substrates
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
176
downloads
The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
107
downloads
Effects of oxygen-glucose deprivation (OGD) on barrier properties and mRNA transcript levels of selected marker proteins in brain endothelial cells/astrocyte co-cultures
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Generation of an iPSC-line (BIONi010C-48) with restored P-glycoprotein functionality following transfection with the human MDR1 gene in the AAVS1 locus
Research output: Contribution to journal › Journal article › Research › peer-review
Neonatal intestinal mucus barrier changes in response to maturity, inflammation, and sodium decanoate supplementation
Research output: Contribution to journal › Journal article › Research › peer-review
The solute carrier SLC7A1 may act as a protein transporter at the blood-brain barrier
Research output: Contribution to journal › Journal article › Research › peer-review