Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions
Research output: Contribution to journal › Journal article › peer-review
To characterize the physicochemical properties of drug-loaded oil-in-water (o/w) and water-in-oil (w/o) Brij 97-based microemulsions in comparison to their blank counterparts and to investigate the influence of microemulsion type on in vitro skin permeation of model hydrophobic drugs and their hydrophilic salts.
|Journal||Journal of Pharmacy and Pharmaceutical Sciences|
|Number of pages||11|
|Publication status||Published - 2007|
- 1-Butanol, Administration, Cutaneous, Anesthetics, Local, Calorimetry, Differential Scanning, Dibucaine, Electric Conductivity, Emulsions, Epidermis, Humans, Hydrogen-Ion Concentration, Hydrophobic and Hydrophilic Interactions, Lidocaine, Molecular Weight, Palmitates, Permeability, Plant Oils, Polyethylene Glycols, Skin Absorption, Tetracaine, Viscosity, Water