Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions
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Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions. / Junyaprasert, Varaporn Buraphacheep; Boonme, Prapaporn; Songkro, Sarunyoo; Krauel, Karen; Rades, Thomas.
In: Journal of Pharmacy and Pharmaceutical Sciences, Vol. 10, No. 3, 2007, p. 288-98.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Transdermal delivery of hydrophobic and hydrophilic local anesthetics from o/w and w/o Brij 97-based microemulsions
AU - Junyaprasert, Varaporn Buraphacheep
AU - Boonme, Prapaporn
AU - Songkro, Sarunyoo
AU - Krauel, Karen
AU - Rades, Thomas
PY - 2007
Y1 - 2007
N2 - To characterize the physicochemical properties of drug-loaded oil-in-water (o/w) and water-in-oil (w/o) Brij 97-based microemulsions in comparison to their blank counterparts and to investigate the influence of microemulsion type on in vitro skin permeation of model hydrophobic drugs and their hydrophilic salts.
AB - To characterize the physicochemical properties of drug-loaded oil-in-water (o/w) and water-in-oil (w/o) Brij 97-based microemulsions in comparison to their blank counterparts and to investigate the influence of microemulsion type on in vitro skin permeation of model hydrophobic drugs and their hydrophilic salts.
KW - 1-Butanol
KW - Administration, Cutaneous
KW - Anesthetics, Local
KW - Calorimetry, Differential Scanning
KW - Dibucaine
KW - Electric Conductivity
KW - Emulsions
KW - Epidermis
KW - Humans
KW - Hydrogen-Ion Concentration
KW - Hydrophobic and Hydrophilic Interactions
KW - Lidocaine
KW - Molecular Weight
KW - Palmitates
KW - Permeability
KW - Plant Oils
KW - Polyethylene Glycols
KW - Skin Absorption
KW - Tetracaine
KW - Viscosity
KW - Water
M3 - Journal article
C2 - 17727792
VL - 10
SP - 288
EP - 298
JO - Journal of Pharmacy and Pharmaceutical Sciences
JF - Journal of Pharmacy and Pharmaceutical Sciences
SN - 1482-1826
IS - 3
ER -
ID: 40354169