Raman spectroscopy in pharmaceutical product design

Department of Pharmacy

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Raman spectroscopy in pharmaceutical product design. / Paudel, Amrit; Raijada, Dhara; Rantanen, Jukka.

In: Advanced Drug Delivery Reviews, Vol. 89, 15.07.2015, p. 3-20.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Paudel, A, Raijada, D & Rantanen, J 2015, 'Raman spectroscopy in pharmaceutical product design', Advanced Drug Delivery Reviews, vol. 89, pp. 3-20. https://doi.org/10.1016/j.addr.2015.04.003

APA

Paudel, A., Raijada, D., & Rantanen, J. (2015). Raman spectroscopy in pharmaceutical product design. Advanced Drug Delivery Reviews, 89, 3-20. https://doi.org/10.1016/j.addr.2015.04.003

Vancouver

Paudel A, Raijada D, Rantanen J. Raman spectroscopy in pharmaceutical product design. Advanced Drug Delivery Reviews. 2015 Jul 15;89:3-20. https://doi.org/10.1016/j.addr.2015.04.003

Author

Paudel, Amrit ; Raijada, Dhara ; Rantanen, Jukka. / Raman spectroscopy in pharmaceutical product design. In: Advanced Drug Delivery Reviews. 2015 ; Vol. 89. pp. 3-20.

Bibtex

@article{29ddefa4e17c48c788894c50310150e6,

title = "Raman spectroscopy in pharmaceutical product design",

abstract = "Almost 100 years after the discovery of the Raman scattering phenomenon, related analytical techniques have emerged as important tools in biomedical sciences. Raman spectroscopy and microscopy are frontier, non-invasive analytical techniques amenable for diverse biomedical areas, ranging from molecular-based drug discovery, design of innovative drug delivery systems and quality control of finished products. This review presents concise accounts of various conventional and emerging Raman instrumentations including associated hyphenated tools of pharmaceutical interest. Moreover, relevant application cases of Raman spectroscopy in early and late phase pharmaceutical development, process analysis and micro-structural analysis of drug delivery systems are introduced. Finally, potential areas of future advancement and application of Raman spectroscopic techniques are discussed.",

keywords = "Chemistry, Pharmaceutical, Drug Delivery Systems, Drug Design, Drug Discovery, Humans, Pharmaceutical Preparations, Quality Control, Spectrum Analysis, Raman, Technology, Pharmaceutical",

author = "Amrit Paudel and Dhara Raijada and Jukka Rantanen",

note = "Copyright {\textcopyright} 2015. Published by Elsevier B.V.",

year = "2015",

month = jul,

day = "15",

doi = "10.1016/j.addr.2015.04.003",

language = "English",

volume = "89",

pages = "3--20",

journal = "Advanced Drug Delivery Reviews",

issn = "0169-409X",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Raman spectroscopy in pharmaceutical product design

AU - Paudel, Amrit

AU - Raijada, Dhara

AU - Rantanen, Jukka

PY - 2015/7/15

Y1 - 2015/7/15

N2 - Almost 100 years after the discovery of the Raman scattering phenomenon, related analytical techniques have emerged as important tools in biomedical sciences. Raman spectroscopy and microscopy are frontier, non-invasive analytical techniques amenable for diverse biomedical areas, ranging from molecular-based drug discovery, design of innovative drug delivery systems and quality control of finished products. This review presents concise accounts of various conventional and emerging Raman instrumentations including associated hyphenated tools of pharmaceutical interest. Moreover, relevant application cases of Raman spectroscopy in early and late phase pharmaceutical development, process analysis and micro-structural analysis of drug delivery systems are introduced. Finally, potential areas of future advancement and application of Raman spectroscopic techniques are discussed.

AB - Almost 100 years after the discovery of the Raman scattering phenomenon, related analytical techniques have emerged as important tools in biomedical sciences. Raman spectroscopy and microscopy are frontier, non-invasive analytical techniques amenable for diverse biomedical areas, ranging from molecular-based drug discovery, design of innovative drug delivery systems and quality control of finished products. This review presents concise accounts of various conventional and emerging Raman instrumentations including associated hyphenated tools of pharmaceutical interest. Moreover, relevant application cases of Raman spectroscopy in early and late phase pharmaceutical development, process analysis and micro-structural analysis of drug delivery systems are introduced. Finally, potential areas of future advancement and application of Raman spectroscopic techniques are discussed.

KW - Chemistry, Pharmaceutical

KW - Drug Delivery Systems

KW - Drug Design

KW - Drug Discovery

KW - Humans

KW - Pharmaceutical Preparations

KW - Quality Control

KW - Spectrum Analysis, Raman

KW - Technology, Pharmaceutical

U2 - 10.1016/j.addr.2015.04.003

DO - 10.1016/j.addr.2015.04.003

M3 - Journal article

C2 - 25868453

VL - 89

SP - 3

EP - 20

JO - Advanced Drug Delivery Reviews

JF - Advanced Drug Delivery Reviews

SN - 0169-409X

ER -

ID: 161624362