Melt extrusion and spray drying of carbamazepine and dipyridamole with polyvinylpyrrolidone/vinyl acetate copolymers

Research output: Contribution to journalJournal articleResearchpeer-review

Carbamazepine and dipyridamole are class II compounds (BCS) whose oral bioavailability is limited by poor solubility. The use of glass solutions to improve the bioavailability of this class of compound has been an area of research for a number of years. The influence of polymer parameters (Tg, hydrophilicity, solubility parameter, and ability to hydrogen bond) on glass solution properties is investigated.
Original languageEnglish
JournalDrug Development and Industrial Pharmacy
Issue number1
Pages (from-to)95-106
Number of pages12
Publication statusPublished - 2008
Externally publishedYes

ID: 40353767