A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication

Standard

A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis. / Zhuang, Guisheng; Poulsen, Nicklas N.; Petersen, Nickolaj J.; Ostergaard, Jesper; Jensen, Henrik.

8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. 2013. p. 1054-1057 6559903.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Communication

Harvard

Zhuang, G, Poulsen, NN, Petersen, NJ, Ostergaard, J & Jensen, H 2013, A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis. in 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013., 6559903, pp. 1054-1057, 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013, Suzhou, China, 07/04/2013. https://doi.org/10.1109/NEMS.2013.6559903

APA

Zhuang, G., Poulsen, N. N., Petersen, N. J., Ostergaard, J., & Jensen, H. (2013). A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis. In 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013 (pp. 1054-1057). [6559903] https://doi.org/10.1109/NEMS.2013.6559903

Vancouver

Zhuang G, Poulsen NN, Petersen NJ, Ostergaard J, Jensen H. A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis. In 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. 2013. p. 1054-1057. 6559903 https://doi.org/10.1109/NEMS.2013.6559903

Author

Zhuang, Guisheng ; Poulsen, Nicklas N. ; Petersen, Nickolaj J. ; Ostergaard, Jesper ; Jensen, Henrik. / A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis. 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013. 2013. pp. 1054-1057

Bibtex

@inproceedings{b144093c305a4719a2044a3615ec3bd8,
title = "A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis",
abstract = "In this paper, we describe a capillary-based microfluidic device utilizing flow induced dispersion analysis (FIDA) for quantitative characterization of biomarkers. The microfluidic device is fabricated by micromilling technology and has incorporated buried optical fibers for light detection. The angle and distance between the fiber guiding the excitation light source and the fiber collecting fluorescent emission light were optimized to enhance signal-to-noise ratio (SNR) and limit of detection (LOD). The prototype achieves a LOD of 50 nM for the fluorescein indicator by using a low-cost Miniature Fiber Optic Spectrometer. The FIDA-based procedure employing fluorescein as the indicator and human serum albumin (HSA) as the analyte is carried out in the microfluidic device.",
keywords = "flow induced dispersion analysis, microfluidics, optical fibers",
author = "Guisheng Zhuang and Poulsen, {Nicklas N.} and Petersen, {Nickolaj J.} and Jesper Ostergaard and Henrik Jensen",
year = "2013",
month = sep,
day = "2",
doi = "10.1109/NEMS.2013.6559903",
language = "English",
isbn = "9781467363525",
pages = "1054--1057",
booktitle = "8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013",
note = "8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013 ; Conference date: 07-04-2013 Through 10-04-2013",

}

RIS

TY - GEN

T1 - A capillary-based microfluidic device incorporating optical fibers for flow induced dispersion analysis

AU - Zhuang, Guisheng

AU - Poulsen, Nicklas N.

AU - Petersen, Nickolaj J.

AU - Ostergaard, Jesper

AU - Jensen, Henrik

PY - 2013/9/2

Y1 - 2013/9/2

N2 - In this paper, we describe a capillary-based microfluidic device utilizing flow induced dispersion analysis (FIDA) for quantitative characterization of biomarkers. The microfluidic device is fabricated by micromilling technology and has incorporated buried optical fibers for light detection. The angle and distance between the fiber guiding the excitation light source and the fiber collecting fluorescent emission light were optimized to enhance signal-to-noise ratio (SNR) and limit of detection (LOD). The prototype achieves a LOD of 50 nM for the fluorescein indicator by using a low-cost Miniature Fiber Optic Spectrometer. The FIDA-based procedure employing fluorescein as the indicator and human serum albumin (HSA) as the analyte is carried out in the microfluidic device.

AB - In this paper, we describe a capillary-based microfluidic device utilizing flow induced dispersion analysis (FIDA) for quantitative characterization of biomarkers. The microfluidic device is fabricated by micromilling technology and has incorporated buried optical fibers for light detection. The angle and distance between the fiber guiding the excitation light source and the fiber collecting fluorescent emission light were optimized to enhance signal-to-noise ratio (SNR) and limit of detection (LOD). The prototype achieves a LOD of 50 nM for the fluorescein indicator by using a low-cost Miniature Fiber Optic Spectrometer. The FIDA-based procedure employing fluorescein as the indicator and human serum albumin (HSA) as the analyte is carried out in the microfluidic device.

KW - flow induced dispersion analysis

KW - microfluidics

KW - optical fibers

UR - http://www.scopus.com/inward/record.url?scp=84883106356&partnerID=8YFLogxK

U2 - 10.1109/NEMS.2013.6559903

DO - 10.1109/NEMS.2013.6559903

M3 - Article in proceedings

AN - SCOPUS:84883106356

SN - 9781467363525

SP - 1054

EP - 1057

BT - 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013

T2 - 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2013

Y2 - 7 April 2013 through 10 April 2013

ER -

ID: 202480321