Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor


  1. 2015
  2. Published

    Formation of covalent di-tyrosine dimers in recombinant α-synuclein

    van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Conformational analysis of large and highly disulfide-stabilized proteins by integrating online electrochemical reduction into an optimized H/D exchange mass spectrometry workflow

    Trabjerg, Esben, Jakobsen, R. U., Mysling, S., Christensen, S., Jørgensen, T. J. D. & Rand, Kasper Dyrberg, 6 Aug 2015, In: Analytical Chemistry. 87, 17, p. 8880–8888 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Probing the Conformational and Functional Consequences of Disulfide Bond Engineering in Growth Hormone by Hydrogen-Deuterium Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation

    Seger, S. T., Breinholt, J., Faber, J. H., Andersen, M. D., Wiberg, C., Schjødt, C. B. & Rand, Kasper Dyrberg, 16 Jun 2015, In: Analytical Chemistry. 87, 12, p. 5973-80 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry

    Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry

    Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Measuring the binding interfaces of protein complexes by gas-phase hydrogen/deuterium exchange mass spectrometry (gas-phase HDX-MS)

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  8. Published

    Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

    Lafleur, J. P., Senkbeil, S., Novotny, J., Nys, G., Bøgelund, N., Rand, Kasper Dyrberg, Foret, F. & Kutter, Jörg P., 2015, In: Lab On a Chip. 15, 10, p. 2162-72 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2014
  10. Published

    Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Dec 2014, In: Analytical Chemistry. 86, 23, p. 11868-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Sites involved in intra- and interdomain allostery associated with the activation of factor VIIa pinpointed by hydrogen-deuterium exchange and electron transfer dissociation mass spectrometry

    Song, H., Olsen, O. H., Persson, E. & Rand, Kasper Dyrberg, 24 Oct 2014, In: The Journal of Biological Chemistry. 289, p. 35388-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling

    Rand, Kasper Dyrberg, Zehl, M. & Jørgensen, T. J. D., 21 Oct 2014, In: Accounts of Chemical Research. 47, 10, p. 3018-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, U., Lohse, B., Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In: A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A conformational investigation of propeptide binding to the integral membrane protein γ-glutamyl carboxylase using nanodisc hydrogen exchange mass spectrometry

    Parker, C. H., Morgan, C. R., Rand, Kasper Dyrberg, Engen, J. R., Jorgenson, J. W. & Stafford, D. W., 11 Mar 2014, In: Biochemistry. 53, 9, p. 1511-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    Pinpointing changes in higher-order protein structure by hydrogen/deuterium exchange coupled to electron transfer dissociation mass spectrometry

    Rand, Kasper Dyrberg, 15 Mar 2013, In: International Journal of Mass Spectrometry. 338, p. 2-10 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. 2012
  19. Published

    Massespektrometri viser vejen til forbedrede proteinlægemidler

    Song, H. & Rand, Kasper Dyrberg, 2012, In: Lægemiddelforskning. 2012, p. 43-46

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation

    Rand, Kasper Dyrberg, Pringle, S. D., Morris, M. & Brown, J. M., 2012, In: Analytical Chemistry. 84, 4, p. 1931-1940

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2011
  22. Published

    Investigation of amide hydrogen back-exchange in Asp and His repeats measured by hydrogen (1H/2H) exchange mass spectrometry

    Rand, Kasper Dyrberg, Lund, F. W., Amon, S. & Jørgensen, Thomas, Apr 2011, In: International Journal of Mass Spectrometry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

    Kim, M., Sun, Z. J., Rand, Kasper Dyrberg, Shi, X., Song, L., Cheng, Y., Fahmy, A. F., Majumdar, S., Ofek, G., Yang, Y., Kwong, P. D., Wang, J., Engen, J. R., Wagner, G. & Reinherz, E. L., 2011, In: Nature Structural and Molecular Biology. 18, 11, p. 1235-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Conformational transitions in the membrane scaffold protein of phospholipid bilayer nanodiscs

    Morgan, C. R., Hebling, C. M., Rand, Kasper Dyrberg, Stafford, D. W., Jorgenson, J. W. & Engen, J. R., 2011, In: Molecular and Cellular Proteomics. 10, 9, p. M111.010876

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    ETD in a traveling wave ion guide at tuned Z-spray ion source conditions allows for site-specific hydrogen/deuterium exchange measurements

    Rand, Kasper Dyrberg, Pringle, S. D., Morris, M., Engen, J. R. & Brown, J. M., 2011, In: Journal of The American Society for Mass Spectrometry. 22, 10, p. 1784-1793

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. False EX1 signatures caused by sample carryover during HX MS analyses

    Fang, J., Rand, Kasper Dyrberg, Beuning, P. J. & Engen, J. R., 2011, In: International Journal of Mass Spectrometry. 302, 1-3, p. 19-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Spatially resolved protein hydrogen exchange measured by matrix-assisted laser desorption ionization in-source decay

    Rand, Kasper Dyrberg, Bache, N., Nedertoft, M. M. & Jørgensen, T., 2011, In: Analytical Chemistry. 83, 23, p. 8859-62 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2010
  29. Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by hydrogen exchange mass spectrometry

    Hebling, C. M., Morgan, C. R., Stafford, D. W., Jorgenson, J. W., Rand, Kasper Dyrberg & Engen, J. R., 2010, In: Analytical Chemistry. 82, 13, p. 5415-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Conformational dynamics of the Escherichia coli DNA polymerase manager proteins UmuD and UmuD'

    Fang, J., Rand, Kasper Dyrberg, Silva, M. C., Wales, T. E., Engen, J. R. & Beuning, P. J., 2010, In: Journal of Molecular Biology. 398, 1, p. 40-53 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Loss of ammonia during electron-transfer dissociation of deuterated peptides as an inherent gauge of gas-phase hydrogen scrambling

    Rand, Kasper Dyrberg, Zehl, M., Jensen, O. & Jørgensen, T., 2010, In: Analytical Chemistry. 82, 23, p. 9755-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34783804