Kasper Dyrberg Rand

Kasper Dyrberg Rand

Professor


  1. 2014
  2. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, U., Lohse, B., Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In: A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Measuring the hydrogen/deuterium exchange of proteins at high spatial resolution by mass spectrometry: overcoming gas-phase hydrogen/deuterium scrambling

    Rand, Kasper Dyrberg, Zehl, M. & Jørgensen, T. J. D., 21 Oct 2014, In: Accounts of Chemical Research. 47, 10, p. 3018-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Sites involved in intra- and interdomain allostery associated with the activation of factor VIIa pinpointed by hydrogen-deuterium exchange and electron transfer dissociation mass spectrometry

    Song, H., Olsen, O. H., Persson, E. & Rand, Kasper Dyrberg, 24 Oct 2014, In: The Journal of Biological Chemistry. 289, p. 35388-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Simple setup for gas-phase H/D exchange mass spectrometry coupled to electron transfer dissociation and ion mobility for analysis of polypeptide structure on a liquid chromatographic time scale

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Dec 2014, In: Analytical Chemistry. 86, 23, p. 11868-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2015
  8. Published

    Getting to the core of protein pharmaceuticals – comprehensive structure analysis by mass spectrometry

    Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2015, In: European Journal of Pharmaceutics and Biopharmaceutics. 93, p. 95-109 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Measuring the binding interfaces of protein complexes by gas-phase hydrogen/deuterium exchange mass spectrometry (gas-phase HDX-MS)

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  10. Published

    Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

    Lafleur, J. P., Senkbeil, S., Novotny, J., Nys, G., Bøgelund, N., Rand, Kasper Dyrberg, Foret, F. & Kutter, Jörg P., 2015, In: Lab On a Chip. 15, 10, p. 2162-72 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry

    Jensen, P. F., Larraillet, V., Schlothauer, T., Kettenberger, H., Hilger, M. & Rand, Kasper Dyrberg, Jan 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 148-61 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Probing the Conformational and Functional Consequences of Disulfide Bond Engineering in Growth Hormone by Hydrogen-Deuterium Exchange Mass Spectrometry Coupled to Electron Transfer Dissociation

    Seger, S. T., Breinholt, J., Faber, J. H., Andersen, M. D., Wiberg, C., Schjødt, C. B. & Rand, Kasper Dyrberg, 16 Jun 2015, In: Analytical Chemistry. 87, 12, p. 5973-80 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Conformational analysis of large and highly disulfide-stabilized proteins by integrating online electrochemical reduction into an optimized H/D exchange mass spectrometry workflow

    Trabjerg, Esben, Jakobsen, R. U., Mysling, S., Christensen, S., Jørgensen, T. J. D. & Rand, Kasper Dyrberg, 6 Aug 2015, In: Analytical Chemistry. 87, 17, p. 8880–8888 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Formation of covalent di-tyrosine dimers in recombinant α-synuclein

    van Maarschalkerweerd, A., Pedersen, M., Peterson, H., Nilsson, M., Nguyen, T., Skamris, T., Rand, Kasper Dyrberg, Vetri, V., Langkilde, Annette Eva & Vestergaard, Bente, 19 Oct 2015, In: Intrinsically Disordered Proteins. 3, 1, p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2016
  16. Published

    A simple sheathless CE-MS interface with a sub-micrometer electrical contact fracture for sensitive analysis of peptide and protein samples

    Nguyen, T. T. T. N., Petersen, Nickolaj J. & Rand, Kasper Dyrberg, 2016, In: Analytica Chimica Acta. 936, p. 157–167 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Analytical Techniques in the Pharmaceutical Sciences

    Leurs, U., Mistarz, U. H. & Rand, Kasper Dyrberg, 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (eds.). Springer Publishing Company, p. 253-289 36 p. (Advances in Delivery Science and Technology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  18. Published

    Direct coupling of a flow-flow electromembrane extraction probe to LC-MS

    Fuchs, D., Gabel-Jensen, C., Jensen, H., Rand, Kasper Dyrberg, Pedersen-Bjergaard, Stig, Hansen, S. H. & Petersen, Nickolaj J., 2016, In: Analytica Chimica Acta. 905, p. 93-99 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Impact of the ‘Austrian’ Mutation of the Amyloid Precursor Protein Transmembrane Helix is Communicated to the Hinge Region

    Stelzer, W., Scharnagl, C., Leurs, U., Rand, Kasper Dyrberg & Langosch, D., 2016, In: ChemistrySelect. 1, 15, p. 4408-4412 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Conformational destabilization of Immunoglobulin G increases the low pH-binding affinity with the Neonatal Fc Receptor

    Walters, B. T., Jensen, P. F., Larraillet, V., Lin, K., Patapoff, T., Schlothauer, T., Rand, Kasper Dyrberg & Zhang, J., 22 Jan 2016, In: Journal of Biological Chemistry. 291, 4, p. 1817-1825 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Probing the Binding Interfaces of Protein Complexes Using Gas-Phase H/D Exchange Mass Spectrometry

    Mistarz, U. H., Brown, J. M., Haselmann, K. F. & Rand, Kasper Dyrberg, 2 Feb 2016, In: Structure. 24, 2, p. 310-318 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Conformational Analysis of Proteins in Highly Concentrated Solutions by Dialysis-Coupled Hydrogen/Deuterium Exchange Mass Spectrometry

    Houde, D., Esmail Nazari, Z., Bou-Assaf, G. M., Weiskopf, A. S. & Rand, Kasper Dyrberg, 9 Feb 2016, In: Journal of the American Society for Mass Spectrometry. 27, 4, p. 669–676 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Gas-phase fragmentation of peptides to increase the spatial resolution of the Hydrogen Exchange Mass Spectrometry experiment

    Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 127-148 22 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Hydrogen exchange: A sensitive analytical window into protein conformation and dynamics

    Jensen, P. F. & Rand, Kasper Dyrberg, Mar 2016, Hydrogen Exchange Mass Spectrometry of protein: Fundamentals, Methods and Applications. Weis, D. (ed.). Wiley, p. 1-17 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  25. Published

    Fully Automated Electro Membrane Extraction Autosampler for LC-MS Systems Allowing Soft Extractions for High-Throughput Applications.

    Fuchs, D., Pedersen-Bjergaard, Stig, Jensen, H., Rand, Kasper Dyrberg, Hansen, S. H. & Petersen, Nickolaj J., 29 May 2016, In: Analytical Chemistry. 88, 13, p. 6797−6804 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Investigating the Role of Artemin Glycosylation

    Danwen, Q., Code, C., Quan, C., Gong, B., Arndt, J., Pepinsky, B., Rand, Kasper Dyrberg & Houde, D., Jun 2016, In: Pharmaceutical Research. 33, 6, p. 1383-1398 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    A novel sensitive sheathless CE-MS device for peptide and protein analysis

    Nguyen, T. T. T. N., Petersen, Nickolaj J. & Rand, Kasper Dyrberg, 8 Jun 2016. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  28. Published

    Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS)

    Esmail Nazari, Z., van de Weert, Marco, Bou-Assaf, G., Houde, D., Weiskopf, A. & Rand, Kasper Dyrberg, 1 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 11, p. 3269–3277 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 34783804